ID   A0A4Z1K161_9HELO        Unreviewed;       595 AA.
AC   A0A4Z1K161;
DT   18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2019, sequence version 1.
DT   28-JAN-2026, entry version 21.
DE   RecName: Full=Tyrosinase copper-binding domain-containing protein {ECO:0000259|PROSITE:PS00497, ECO:0000259|PROSITE:PS00498};
GN   ORFNames=BELL_0027g00260 {ECO:0000313|EMBL:TGO79635.1};
OS   Botrytis elliptica.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Sclerotiniaceae; Botrytis.
OX   NCBI_TaxID=278938 {ECO:0000313|EMBL:TGO79635.1, ECO:0000313|Proteomes:UP000297229};
RN   [1] {ECO:0000313|EMBL:TGO79635.1, ECO:0000313|Proteomes:UP000297229}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Be9601 {ECO:0000313|EMBL:TGO79635.1,
RC   ECO:0000313|Proteomes:UP000297229};
RA   Valero-Jimenez C.A., Tapia P., Veloso J., Silva-Moreno E., Staats M.,
RA   Valdes J.H., Van Kan J.A.L.;
RT   "Comparative genomics of Botrytis spp.";
RL   Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Cu(2+); Xref=ChEBI:CHEBI:29036;
CC         Evidence={ECO:0000256|ARBA:ARBA00001973};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:TGO79635.1}.
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DR   EMBL; PQXM01000027; TGO79635.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A4Z1K161; -.
DR   STRING; 278938.A0A4Z1K161; -.
DR   OrthoDB; 1658288at2759; -.
DR   Proteomes; UP000297229; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 1.
DR   InterPro; IPR008922; Di-copper_centre_dom_sf.
DR   InterPro; IPR050316; Tyrosinase/Hemocyanin.
DR   InterPro; IPR041640; Tyrosinase_C.
DR   InterPro; IPR002227; Tyrosinase_Cu-bd.
DR   PANTHER; PTHR11474:SF131; TYROSINASE COPPER-BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR11474; TYROSINASE FAMILY MEMBER; 1.
DR   Pfam; PF00264; Tyrosinase; 1.
DR   Pfam; PF18132; Tyrosinase_C; 1.
DR   PRINTS; PR00092; TYROSINASE.
DR   SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR   PROSITE; PS00497; TYROSINASE_1; 1.
DR   PROSITE; PS00498; TYROSINASE_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Monooxygenase {ECO:0000256|ARBA:ARBA00023033};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000297229}.
FT   DOMAIN          112..129
FT                   /note="Tyrosinase copper-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS00497"
FT   DOMAIN          306..317
FT                   /note="Tyrosinase copper-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS00498"
SQ   SEQUENCE   595 AA;  65834 MW;  2C7DFD54315DC19F CRC64;
     MIIKYPYFPW GLLACSIFIT YGNAQYYPIT GVTTGINPNT KARPFRQNID DLQNNIQQWS
     LYIQALLAMQ AANEYTDGLS YFQLAGIHGR PYVAWDGVNQ AIAAPTTGYC THDSVLFTTW
     HRPYLALFEQ VLASYAQTIA KSYISTLYPA YQAAADNLRI PFWDWGASPS MPSITNVATI
     SIVLPSGATA YVNNPLFRYN FQNKPLNQQQ FPPGDSDGYM AQYNWTVRNP DNLGNGQSDF
     NAANTNLQNA GLGDQVWTAI MKSSNFNSFA TMAVSGASIE SPHGAVHVLV GGAYGHMSFL
     SYSGFDPIFW LHHANVDRVL SMYQAINPST FITGLIDWYG TYTITPGTID TASSPLKPFA
     ITSSTFFTSN TCRSMSQLGY SYPEIMDWNM TAEKMTSYVT GRVNELYNSD GSNSKIKKRN
     FDSRELFSEK QHEGPSTNKT LREWTAALSV SKLDLQGQRF IIRLFLGKIP ESPEEWGRSE
     SLVGSLVILP PPGAVSNDAT KALAYDEIII LREPAIGGSY KGQDDDGNGE GTEEFLKKNL
     RWRAQLLDNT PLHATSLPTL KIIVGDEVVA MPHDITKKPV YGTKTLHPDI VVGGN
//