ID A0A4Z2B4B9_9TELE Unreviewed; 847 AA.
AC A0A4Z2B4B9;
DT 18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2019, sequence version 1.
DT 08-OCT-2025, entry version 21.
DE RecName: Full=Cold shock domain-containing protein E1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=fugu_006628 {ECO:0000313|EMBL:TNM86398.1};
OS Takifugu bimaculatus.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=433685 {ECO:0000313|EMBL:TNM86398.1, ECO:0000313|Proteomes:UP000516260};
RN [1] {ECO:0000313|EMBL:TNM86398.1, ECO:0000313|Proteomes:UP000516260}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TB-2018 {ECO:0000313|EMBL:TNM86398.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:TNM86398.1};
RA Xu P., Liu B., Zhou Z.;
RT "The sequence and de novo assembly of Takifugu bimaculatus genome using
RT PacBio and Hi-C technologies.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the UNR family. {ECO:0000256|ARBA:ARBA00044751}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TNM86398.1}.
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DR EMBL; SWLE01000020; TNM86398.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4Z2B4B9; -.
DR Proteomes; UP000516260; Chromosome 7.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:1905172; F:RISC complex binding; IEA:UniProtKB-ARBA.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR CDD; cd04458; CSP_CDS; 2.
DR FunFam; 2.40.50.140:FF:000055; Cold shock domain containing E1, RNA-binding; 1.
DR FunFam; 2.40.50.140:FF:000088; cold shock domain-containing protein E1 isoform X1; 1.
DR FunFam; 2.40.50.140:FF:000094; cold shock domain-containing protein E1 isoform X1; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 6.
DR InterPro; IPR011129; CSD.
DR InterPro; IPR019844; CSD_CS.
DR InterPro; IPR056400; CSDE1.
DR InterPro; IPR002059; CSP_DNA-bd.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR024642; SUZ-C.
DR PANTHER; PTHR12913:SF2; COLD SHOCK DOMAIN-CONTAINING PROTEIN E1 ISOFORM X1; 1.
DR PANTHER; PTHR12913; UNR PROTEIN N-RAS UPSTREAM GENE PROTEIN; 1.
DR Pfam; PF00313; CSD; 5.
DR Pfam; PF23456; CSDE1; 4.
DR Pfam; PF12901; SUZ-C; 1.
DR SMART; SM00357; CSP; 5.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 5.
DR PROSITE; PS00352; CSD_1; 4.
DR PROSITE; PS51857; CSD_2; 5.
DR PROSITE; PS51938; SUZ_C; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000516260};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 78..142
FT /note="CSD"
FT /evidence="ECO:0000259|PROSITE:PS51857"
FT DOMAIN 236..298
FT /note="CSD"
FT /evidence="ECO:0000259|PROSITE:PS51857"
FT DOMAIN 400..464
FT /note="CSD"
FT /evidence="ECO:0000259|PROSITE:PS51857"
FT DOMAIN 567..630
FT /note="CSD"
FT /evidence="ECO:0000259|PROSITE:PS51857"
FT DOMAIN 722..786
FT /note="CSD"
FT /evidence="ECO:0000259|PROSITE:PS51857"
FT DOMAIN 797..838
FT /note="SUZ-C"
FT /evidence="ECO:0000259|PROSITE:PS51938"
FT REGION 1..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 13..35
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 847 AA; 94233 MW; CC92FCB87FFA4553 CRC64;
MERGSSEPPV PRNTGSAPST STDPMPIPRS SSVSFHPQPG CKKHKRTPLY QRSMSFDPSM
LHNNGHTAYA NGTGPGIRET GVVEKLLTSY GFIQCSERQA RLFFHCSQYN GNLQELKIGD
DVEFEVAPDR RTGKPIAVKL LKIKPEMLTE ERISGQVVSA VPTHLDGKSA PGQVPTGSVC
YERNGEVFYL TYTSDDVEGN MRVDMGDKVS FYIETNKLTG AVSARNIQLV KKKQLRCQGV
VCATKEAFGF IERADVVKEI FFHYSEFKGD LEALQAGDDV EFTIKDRNGK EVATDVRLLP
QGTVIFEDIS IEQFEGTVVK VIPKVPTKNQ NDPLPGRISA RIGFTEKELP FGEKDTKSKV
TLLEGDHIQF NISTDRRDKL ERATNIDILP DTFNFTKETR EMGVIAAIRD GFGFIKCVDR
DARMFFHFSE VLEETQLHIS DEVEFTVVPD MLSAQRNHAV RIKKLPKGTV SFHTQSEQRF
VGVVEKDTVA TKNSSPNKNK EKEPDEGVIV YDDCGLKVSV PYHTKDLEAG IHLQAGDKVE
FSISEVKRTG LQSAVSVRLL NRTVSKKVYG FVATLKDNFG FIETANHDQE IFFHYSEMCG
DLDSLELGDT VEYSPSKGKG NKISAEKVTK VAPVNALGED IDATVITGKV IRPLRSVDPS
QSEYQGLIEV IEEGASKCQK IPFGIMSMAN KADCLQKGEP VKFQLCTVAQ TGQKMACIVV
PQRRALVECV KDQFGFITYE VGESKKLFFH VKEVQDSLEL QTGDEVEFTV VLNQRTGKFS
ACNVRRISEA PKPVVTPRPE RLVKRLKSVT LDDANAPRLI VLRQPRGPDS TKGFGLERKV
RQPGIID
//
