ID   A0A507F3B3_9FUNG        Unreviewed;       755 AA.
AC   A0A507F3B3;
DT   18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2019, sequence version 1.
DT   02-APR-2025, entry version 19.
DE   RecName: Full=Alpha 1,4-glycosyltransferase domain-containing protein {ECO:0000259|Pfam:PF04572};
GN   ORFNames=CcCBS67573_g06448 {ECO:0000313|EMBL:TPX70743.1};
OS   Chytriomyces confervae.
OC   Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC   Chytridiomycota incertae sedis; Chytridiomycetes; Chytridiales;
OC   Chytriomycetaceae; Chytriomyces.
OX   NCBI_TaxID=246404 {ECO:0000313|EMBL:TPX70743.1, ECO:0000313|Proteomes:UP000320333};
RN   [1] {ECO:0000313|EMBL:TPX70743.1, ECO:0000313|Proteomes:UP000320333}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 675.73 {ECO:0000313|EMBL:TPX70743.1,
RC   ECO:0000313|Proteomes:UP000320333};
RX   PubMed=31209237; DOI=.1038/s41598-019-45128-9;
RA   van de Vossenberg B.T.L.H., Warris S., Nguyen H.D.T.,
RA   van Gent-Pelzer M.P.E., Joly D.L., van de Geest H.C., Bonants P.J.M.,
RA   Smith D.S., Levesque C.A., van der Lee T.A.J.;
RT   "Comparative genomics of chytrid fungi reveal insights into the obligate
RT   biotrophic and pathogenic lifestyle of Synchytrium endobioticum.";
RL   Sci. Rep. 9:8672-8672(2019).
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC       {ECO:0000256|ARBA:ARBA00004323}; Single-pass type II membrane protein
CC       {ECO:0000256|ARBA:ARBA00004323}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 32 family.
CC       {ECO:0000256|ARBA:ARBA00009003}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:TPX70743.1}.
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DR   EMBL; QEAP01000276; TPX70743.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A507F3B3; -.
DR   STRING; 246404.A0A507F3B3; -.
DR   OrthoDB; 409543at2759; -.
DR   Proteomes; UP000320333; Unassembled WGS sequence.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016758; F:hexosyltransferase activity; IEA:UniProtKB-ARBA.
DR   GO; GO:0006688; P:glycosphingolipid biosynthetic process; IEA:TreeGrafter.
DR   Gene3D; 3.90.550.20; -; 2.
DR   InterPro; IPR007652; A1-4-GlycosylTfrase_dom.
DR   InterPro; IPR051981; Glycosyltransf_32.
DR   InterPro; IPR007577; GlycoTrfase_DXD_sugar-bd_CS.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   PANTHER; PTHR12042:SF21; ALPHA1,4-GALACTOSYLTRANSFERASE 1-RELATED; 1.
DR   PANTHER; PTHR12042; LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE ALPHA- 1,4-GALACTOSYLTRANSFERASE; 1.
DR   Pfam; PF04572; Gb3_synth; 1.
DR   Pfam; PF04488; Gly_transf_sug; 1.
DR   SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 2.
PE   3: Inferred from homology;
KW   Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW   Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000320333};
KW   Transferase {ECO:0000256|ARBA:ARBA00022676};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        20..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          590..724
FT                   /note="Alpha 1,4-glycosyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF04572"
SQ   SEQUENCE   755 AA;  86184 MW;  30FA22BDCB9E1390 CRC64;
     MKLTITSTPS FGGRSFRRLF VWTCLLTFIA FSSYHTFKRV RIKQVSDKDA FPMDTVNATF
     MHAPHIMAET ALSQSCAAFQ NEVSTAYWRR VEQMNTTQPP AKLPDNVSEK PLEIVFINHV
     GRSMDPVNLC ALESAARHNP TLKITLHSKD ATRLQIRMQT WRNRINFMYN SNQQFGEDRI
     EFVESNFTAA FDGTILAPWY AELLEMNSTL FEAQSTNLMA AYQLAVMWKN GGVFPNAKFV
     SVNPLPPLAE RIIAFQSYSG EKYFGDSFLS LRPRDALIWI MMKKFLDAFR YKRNTPGWHY
     QLGPSLNWAI HSYCSETSPP AVLCTFDPRS GEVLFSFDDA FAAKTKPWTD MCPALNKLVN
     TAVGLTLNKP IFVESAWNTL MDINCPVVVS SFAPKALGFY DGEGCATFEQ RAQTPGTTFL
     TASGEEISES QASLLASNIP KRINFLLFND HFKNLRYLCS IESAARQNPN HDIFVYAKNA
     PDFLKESVNW FLHAEKRNPG LRNQLHILDL DWDDLFRGTP LESWWRRGTW MQSRWPDQNL
     GNAARLAILW KEGGVYLDMD IISLNPVSGM GRSLAWQLRP NILNNAYFSL EKGDEFAWRM
     MENFVSGFNG TIWGRNGPRM VERTHVRYCR PNLALRLLNR LTGNLSQKMC DFNIAPSERL
     YPIAFNHKKS FLKPARGSCD LLKTMSERSI GIHWWNKGLK GTNVGVGSVL ETVMKNHCPA
     MFDAYYPEEI GFFSEDAIRT GKAKFWRGYE KNDGF
//