ID A0A507FT88_9FUNG Unreviewed; 349 AA.
AC A0A507FT88;
DT 18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2019, sequence version 1.
DT 05-FEB-2025, entry version 12.
DE SubName: Full=2-dehydropantoate 2-reductase {ECO:0000313|EMBL:TPX78047.1};
GN Name=PAN5C {ECO:0000313|EMBL:TPX78047.1};
GN ORFNames=CcCBS67573_g00650 {ECO:0000313|EMBL:TPX78047.1};
OS Chytriomyces confervae.
OC Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC Chytridiomycota incertae sedis; Chytridiomycetes; Chytridiales;
OC Chytriomycetaceae; Chytriomyces.
OX NCBI_TaxID=246404 {ECO:0000313|EMBL:TPX78047.1, ECO:0000313|Proteomes:UP000320333};
RN [1] {ECO:0000313|EMBL:TPX78047.1, ECO:0000313|Proteomes:UP000320333}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 675.73 {ECO:0000313|EMBL:TPX78047.1,
RC ECO:0000313|Proteomes:UP000320333};
RX PubMed=31209237; DOI=.1038/s41598-019-45128-9;
RA van de Vossenberg B.T.L.H., Warris S., Nguyen H.D.T.,
RA van Gent-Pelzer M.P.E., Joly D.L., van de Geest H.C., Bonants P.J.M.,
RA Smith D.S., Levesque C.A., van der Lee T.A.J.;
RT "Comparative genomics of chytrid fungi reveal insights into the obligate
RT biotrophic and pathogenic lifestyle of Synchytrium endobioticum.";
RL Sci. Rep. 9:8672-8672(2019).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TPX78047.1}.
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DR EMBL; QEAP01000010; TPX78047.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A507FT88; -.
DR STRING; 246404.A0A507FT88; -.
DR OrthoDB; 3609at2759; -.
DR Proteomes; UP000320333; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:TreeGrafter.
DR Gene3D; 1.10.1040.10; N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR013752; KPA_reductase.
DR InterPro; IPR051402; KPR-Related.
DR InterPro; IPR013332; KPR_N.
DR PANTHER; PTHR21708:SF26; 2-DEHYDROPANTOATE 2-REDUCTASE; 1.
DR PANTHER; PTHR21708; PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE; 1.
DR Pfam; PF02558; ApbA; 1.
DR Pfam; PF08546; ApbA_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000320333}.
FT DOMAIN 10..175
FT /note="Ketopantoate reductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02558"
FT DOMAIN 211..334
FT /note="Ketopantoate reductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08546"
SQ SEQUENCE 349 AA; 37380 MW; 98963C32D940E8FD CRC64;
MHSESSSGNI LIIGGGACGA FHGHLLVQAG LNVAMVCRSN FESVKEHGFD IATGPGENSV
KFYPPTMFPN TSEAASSGLL FEHILVFTKA TPSSDAVGLV APVLATSFAN NTTSVKSISL
WQNGIGVEDS LAVFLASNKA LHSIALVSCV VYAGISRREG TLIRTAGTQK TVAGLVDYLS
PASPHKQQHA MQLQHLEALV APSFSLSVIA NIQPARWQKS LWSASIGLVS LVGRSADVHT
VVRTQEPLIR EVMKEIVHAA GQVLGSPLLE DEEATFEDLL TIPLDESFKP DIVLDWESGR
ELDHQVQYGN LIRAAKAAGA DVPRLEALYS VLQLMVFQRQ LSNAPHLDQ
//
