ID A0A508TZA4_9BRAD Unreviewed; 563 AA.
AC A0A508TZA4;
DT 18-SEP-2019, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2019, sequence version 1.
DT 18-JUN-2025, entry version 19.
DE SubName: Full=Aspartate/alanine antiporter {ECO:0000313|EMBL:VIO79526.1};
GN Name=aspT_1 {ECO:0000313|EMBL:VIO79526.1};
GN ORFNames=CI1B_78590 {ECO:0000313|EMBL:VIO79526.1};
OS Bradyrhizobium ivorense.
OC Bacteria; Pseudomonadati; Pseudomonadota; Alphaproteobacteria;
OC Hyphomicrobiales; Nitrobacteraceae; Bradyrhizobium.
OX NCBI_TaxID=2511166 {ECO:0000313|EMBL:VIO79526.1, ECO:0000313|Proteomes:UP000328092};
RN [1] {ECO:0000313|EMBL:VIO79526.1, ECO:0000313|Proteomes:UP000328092}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CI-1B {ECO:0000313|EMBL:VIO79526.1,
RC ECO:0000313|Proteomes:UP000328092};
RA Pothier F. J.;
RL Submitted (FEB-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC -!- SIMILARITY: Belongs to the AAE transporter (TC 2.A.81) family.
CC {ECO:0000256|ARBA:ARBA00009854}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CAADFC020000033; VIO79526.1; -; Genomic_DNA.
DR RefSeq; WP_139864358.1; NZ_CAADFC020000033.1.
DR AlphaFoldDB; A0A508TZA4; -.
DR OrthoDB; 5166626at2; -.
DR Proteomes; UP000328092; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 1.
DR InterPro; IPR050144; AAE_transporter.
DR InterPro; IPR022457; Asp_Ala_antiprt.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR InterPro; IPR006512; YidE_YbjL.
DR NCBIfam; TIGR03802; Asp_Ala_antiprt; 1.
DR NCBIfam; TIGR01625; YidE_YbjL_dupl; 1.
DR PANTHER; PTHR30445:SF9; -; 1.
DR PANTHER; PTHR30445; K(+)_H(+) ANTIPORTER SUBUNIT KHTT; 1.
DR Pfam; PF06826; Asp-Al_Ex; 2.
DR Pfam; PF02080; TrkA_C; 2.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 2.
DR PROSITE; PS51202; RCK_C; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000328092};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 35..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 63..82
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 94..111
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 161..186
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 385..406
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 412..431
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 452..474
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 480..503
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 538..562
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 207..285
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
FT DOMAIN 291..378
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
SQ SEQUENCE 563 AA; 59583 MW; 9897AB198B1B2937 CRC64;
MIDWLFQTLR TYPEIAIFLS LALGYYFGSF TFKGLGLGAV TATLIAAVII GQIGITISGP
LKPFFFLMFL FAIGYGVGPQ FVRGIAQDGV PQAIFAAVVC VFCLLSAYFG AKIAGYDVGS
AIGLYAGSQT ISASMGLATD AINRLGLPAD EAKKLLDAMP VAYAVTYIFG TVGSAIVLAL
LGPALLGIDL EAACKKYEEE HGGKKELGGP GTSWHQFDVR AYRVRERGPV VGKTVAQAEA
LIPDHRVFVL RLRQGGKIVE ATSDTVIHAG DVVAVAGRRD VLVQLIGEQA EEVDDRELLA
VPIEGVDVYV TSKDVDGKTL EELAREPGAR GVFLRRIVRG AIATEIPILP NTKINRGDIV
TLVGRTSDVA ATTKMLGRPD RATDVADVAF IGAAIAIGAL VGAFVYKIGS VPLTLSTSGG
ALISGLFFGW LRSVHPTFGR IPSPTVWFMN SVGLNVFIAV VGISSGPGFV AGLQKLGFSL
FLWGVIVTTV PLILAMFVGK YVFRFHDAIL LGCCSGARTT TASLGMINDR AKSQIPGLGY
TVTYAVGNTL LTIWGMVLVM MMT
//
