ID A0A512CZ61_9MICO Unreviewed; 625 AA.
AC A0A512CZ61;
DT 16-OCT-2019, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2019, sequence version 1.
DT 28-JAN-2026, entry version 27.
DE RecName: Full=Selenocysteine-specific elongation factor {ECO:0000256|ARBA:ARBA00015953};
DE AltName: Full=SelB translation factor {ECO:0000256|ARBA:ARBA00031615};
GN ORFNames=TAE01_13230 {ECO:0000313|EMBL:GEO29513.1};
OS Terrabacter aerolatus.
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Micrococcales;
OC Intrasporangiaceae; Terrabacter.
OX NCBI_TaxID=422442 {ECO:0000313|EMBL:GEO29513.1, ECO:0000313|Proteomes:UP000321534};
RN [1] {ECO:0000313|EMBL:GEO29513.1, ECO:0000313|Proteomes:UP000321534}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 106305 {ECO:0000313|EMBL:GEO29513.1,
RC ECO:0000313|Proteomes:UP000321534};
RA Hosoyama A., Uohara A., Ohji S., Ichikawa N.;
RT "Whole genome shotgun sequence of Terrabacter aerolatus NBRC 106305.";
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Translation factor necessary for the incorporation of
CC selenocysteine into proteins. It probably replaces EF-Tu for the
CC insertion of selenocysteine directed by the UGA codon. SelB binds GTP
CC and GDP. {ECO:0000256|ARBA:ARBA00025526}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GEO29513.1}.
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DR EMBL; BJYX01000005; GEO29513.1; -; Genomic_DNA.
DR RefSeq; WP_147064667.1; NZ_BAAARO010000002.1.
DR AlphaFoldDB; A0A512CZ61; -.
DR OrthoDB; 9803139at2; -.
DR Proteomes; UP000321534; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00475; selB; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:GEO29513.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00023134};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000321534}.
FT DOMAIN 1..170
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 625 AA; 64919 MW; F26AF24D3A846740 CRC64;
MHVIATAGHV DHGKSTLVRA LTGIEPDRWA EERRRGMTID LGYAWTTLPS GADVAFVDVP
GHQRFIGNML AGLGPAPAVV LVVAADEGWR PQSAEHLAAV DALGISRGLV VVTRSDLADP
GPALAEALDH VGRTSLAGSA ALAVSARTGQ GLDALRAALD DLVAALPAPE RDARTRLWVD
RSFSVRGSGT VVTGTLGAGT VRVGDELVVH RTDGTSRSVG VRGLQSLGRA RDEVAAVARV
AVNLRGVGVD EVARGDVLLT PRAWHVTRTL DVRVVGTVSA SPSGVPGAGP VGALGAVGAV
GAVTGPLVPD PLPSHVMLHV GTLAVEARVR PLGPGAVRLA LPAALPVVAG DRILLRDPGS
RRVVGAVVVD ADPPVLDRRG SAARRAAVVR SLDGAPDLAR EVARRGCMRE SEAESLGIVV
PPGDRPGATV ARRGAWLVDD ATWQVAADRL HAAVRGRADA EPIDPVLALE AARAAAGVPD
RALVTELAVT AGLEVRDGRV GLPGRRAVLS SGAEAGLSRI EERLRQRPFT APEQHELDDA
GLGSRELAAA EGTGRILRLP GGVVLLPNAP ALAMRELAAL PQPFTTSDAR LALDSTRRIV
IPLLEHLDAR GWTRRLDGSH REVRR
//
