ID   A0A518EQ70_9BACT        Unreviewed;      1867 AA.
AC   A0A518EQ70;
DT   16-OCT-2019, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2019, sequence version 1.
DT   18-JUN-2025, entry version 13.
DE   SubName: Full=MG2 domain protein {ECO:0000313|EMBL:QDV06229.1};
GN   ORFNames=Poly30_17360 {ECO:0000313|EMBL:QDV06229.1};
OS   Saltatorellus ferox.
OC   Bacteria; Pseudomonadati; Planctomycetota; Planctomycetia;
OC   Planctomycetia incertae sedis; Saltatorellus.
OX   NCBI_TaxID=2528018 {ECO:0000313|EMBL:QDV06229.1, ECO:0000313|Proteomes:UP000320390};
RN   [1] {ECO:0000313|EMBL:QDV06229.1, ECO:0000313|Proteomes:UP000320390}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Poly30 {ECO:0000313|EMBL:QDV06229.1,
RC   ECO:0000313|Proteomes:UP000320390};
RA   Wiegand S., Jogler M., Boedeker C., Pinto D., Vollmers J., Rivas-Marin E.,
RA   Kohn T., Peeters S.H., Heuer A., Rast P., Oberbeckmann S., Bunk B.,
RA   Jeske O., Meyerdierks A., Storesund J.E., Kallscheuer N., Luecker S.,
RA   Lage O.M., Pohl T., Merkel B.J., Hornburger P., Mueller R.-W., Bruemmer F.,
RA   Labrenz M., Spormann A.M., Op den Camp H., Overmann J., Amann R.,
RA   Jetten M.S.M., Mascher T., Medema M.H., Devos D.P., Kaster A.-K.,
RA   Ovreas L., Rohde M., Galperin M.Y., Jogler C.;
RT   "Deep-cultivation of Planctomycetes and their phenomic and genomic
RT   characterization uncovers novel biology.";
RL   Submitted (FEB-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the protease inhibitor I39 (alpha-2-
CC       macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.
CC       {ECO:0000256|ARBA:ARBA00010556}.
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DR   EMBL; CP036434; QDV06229.1; -; Genomic_DNA.
DR   OrthoDB; 9767116at2; -.
DR   Proteomes; UP000320390; Chromosome.
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; IEA:InterPro.
DR   Gene3D; 1.50.10.20; -; 1.
DR   Gene3D; 2.60.40.1930; -; 1.
DR   InterPro; IPR011625; A2M_N_BRD.
DR   InterPro; IPR021868; Alpha_2_Macroglob_MG3.
DR   InterPro; IPR041246; Bact_MG10.
DR   InterPro; IPR001599; Macroglobln_a2.
DR   InterPro; IPR002890; MG2.
DR   InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR   InterPro; IPR051802; YfhM-like.
DR   PANTHER; PTHR40094; ALPHA-2-MACROGLOBULIN HOMOLOG; 1.
DR   PANTHER; PTHR40094:SF1; UBIQUITIN DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00207; A2M; 1.
DR   Pfam; PF07703; A2M_BRD; 1.
DR   Pfam; PF17973; bMG10; 1.
DR   Pfam; PF11974; bMG3; 1.
DR   Pfam; PF01835; MG2; 1.
DR   SMART; SM01360; A2M; 1.
DR   SMART; SM01359; A2M_N_2; 1.
DR   SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000320390}.
FT   DOMAIN          975..1117
FT                   /note="Alpha-2-macroglobulin bait region"
FT                   /evidence="ECO:0000259|SMART:SM01359"
FT   DOMAIN          1184..1271
FT                   /note="Alpha-2-macroglobulin"
FT                   /evidence="ECO:0000259|SMART:SM01360"
SQ   SEQUENCE   1867 AA;  200636 MW;  F1A39DE4D2155645 CRC64;
     MGRTPFRAAP RSTFVAAFAA LLVLNAAGWK LYGERSSTVL AAAATEGDFG TTDTISASGQ
     PFVTLAAALP TRDVGQADRL IVALGGTAEV DPNSADDEPL PDLLDPPFTV EPFLDGRWEW
     ESRTRLAFLL DEPLGECKEV RMRPTAALEK LLGRAVDPKF EARWTSAPLE IQAVHVMSVG
     KDTVTARVTL NAELDPSEVL AALKLTLPGA TEALALTPVA SLTRNGDGQG SGFHHDFRFP
     RPDGEATHLE WHFDHPLCHL GESKGLIWRT RRKAPPLLEV PRRFALLRHG ERVFSDRDGG
     RIDFEFSASL EPTADAPEIE VRPLVPHLSV RSSGTRLVVE GDFEAGATYS VTLPENVLAS
     NGETLNAARI VSIEMPRREP QLAIPVWRGT LSPEGHLSLE LMATAVDAVR VKATKVLPGN
     LVEHVRGESR RYTSAQVLSE TYRLPGSAAG GPTERHALDL RSLLERDGET LAGVYHLEVS
     STESRWISDY ASVRISDLGT TARRDAEGLH FWVHSIATGA AVENATITAL TVQDQTLGRA
     TTNGDGYAFI ACPRTDSSQG AGDGTAPFLA VIETGQDLAY LELESSTWDV PREVACGRTI
     PGAADVFAYT ERNLYRPGDR VYLTGIARSN AGVVHARPVD VTLTRPDGAV MLEETVLPDP
     GQGLFHLVHT TSQNARTGTW KFAFRDSASG ESIGSMTFGV EAFLPARMAL TSTSERETAE
     AAPSSRVVAR SLAGTSTEGF EAELSTRWSP LRFTSTRFPL FSFEAESDDR SERRDSSQVA
     LLADGSAAAE LPGFRDLAPG LWRASNTWTV TEPGSRSAVA NSALKVDTGK EHRGLRIDRV
     AGLGPDATEA TKGAGTGVVG VGEPFHVLGL CVGADDLPMA EEVLYLSVDR IESRYVLDSA
     GGGLRWTLEK TVTAVASLAL EPDPFGVLRA ALTCPEAGEY RLTLRGEDAK TATILGFHAA
     ENPDRFQPTQ PSERVTLTPE FRAVSPGSSV GFRIESPFDG SALVTAEDGR LRWQQRIQLE
     NGRGEIEIPM ADDVRGGLVV SCQVTRPLNS KADTWRPHRA YGWARIETLH HDHQLGVSIA
     APERVRPGEM ATVTVEAPTS PRAAVHLWAV DEGLRLAGGH RTPDPLEHFL GARAFRGSAT
     DTWSTLLPDV ELPASISRIG GDSGLAHEAR RRAPEAVRVT PAIVWNEAVR LGDDGRMTTT
     LRVPDFTGEL TWMAVVVDGD RYGSWQEATT VAGEIPIALG LPRFAAPGDQ LRVKMAFENT
     GESAASVRPR LEVTGAGEVI DGPDEGVLTL EPGERHVAWF SIEATRSGRI EGAAWLEGQF
     ADGRAAHERV AIDLPVRSGR PFVTYSSGVS LDASEGRGLS LDLAERLGIS AGERGNCELR
     VSSSAGLSLH PAGAYLSEYP HGCAEQTASR IFAALSLHAL RAKSDDESHA RTETADRVTR
     GFLRLASMQV MDGGIGYWPG SRSSSDWATL HVADVIAAAR DLGFEVPARL TERLAGYLDA
     ELRSTKSAAE RARLVHAAAA LGTMHAGWMR RLEEQQASLG RAGRAYLAAA LGLAGEKRRA
     LALIESRSEE AEPVTADSFA YLDSLVRTVA LELRVLLSID PYHRGVHERV ALLEAERSGS
     SGRWRNTVDN AAALAALARH AQVFDAGQAD WQLAARLSTP EGTSGLDVVE VTSDAESLVA
     IPAGVSALDF DVTGSGPVFL RLSATGQCSA SAPGADRGLR CRRRLFDGQG LELDSRNVRH
     GDLVFVELTL ATDGRSDVRD VAMVDPLPGG LEIETPKLLT EFPWHAAKQQ KESDFRATPS
     GSEDRVEFLD DRVLLYATAR TEVRAFRYAA RAVALGSFEH GPVQAEAMYA PEVSSVGGST
     GQIHVTE
//