ID A0A540VFZ1_9CHLR Unreviewed; 644 AA.
AC A0A540VFZ1;
DT 16-OCT-2019, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2019, sequence version 1.
DT 28-JAN-2026, entry version 27.
DE RecName: Full=Selenocysteine-specific elongation factor {ECO:0000256|ARBA:ARBA00015953};
DE AltName: Full=SelB translation factor {ECO:0000256|ARBA:ARBA00031615};
GN Name=selB {ECO:0000313|EMBL:TQE95671.1};
GN ORFNames=FKZ61_11140 {ECO:0000313|EMBL:TQE95671.1};
OS Litorilinea aerophila.
OC Bacteria; Bacillati; Chloroflexota; Caldilineae; Caldilineales;
OC Caldilineaceae; Litorilinea.
OX NCBI_TaxID=1204385 {ECO:0000313|EMBL:TQE95671.1, ECO:0000313|Proteomes:UP000317371};
RN [1] {ECO:0000313|EMBL:TQE95671.1, ECO:0000313|Proteomes:UP000317371}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-2444 {ECO:0000313|EMBL:TQE95671.1,
RC ECO:0000313|Proteomes:UP000317371};
RA Maclea K.S., Maurais E.G., Iannazzi L.C.;
RT "Genome sequence of Litorilinea aerophila BAA-2444.";
RL Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Translation factor necessary for the incorporation of
CC selenocysteine into proteins. It probably replaces EF-Tu for the
CC insertion of selenocysteine directed by the UGA codon. SelB binds GTP
CC and GDP. {ECO:0000256|ARBA:ARBA00025526}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TQE95671.1}.
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DR EMBL; VIGC01000012; TQE95671.1; -; Genomic_DNA.
DR RefSeq; WP_141610206.1; NZ_VIGC02000012.1.
DR AlphaFoldDB; A0A540VFZ1; -.
DR InParanoid; A0A540VFZ1; -.
DR OrthoDB; 9804504at2; -.
DR Proteomes; UP000317371; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR CDD; cd03696; SelB_II; 1.
DR CDD; cd15491; selB_III; 1.
DR Gene3D; 1.10.10.2770; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR015190; Elong_fac_SelB-wing-hlx_typ-2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR005225; Small_GTP-bd.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00475; selB; 1.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF09106; WHD_2nd_SelB; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:TQE95671.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000317371}.
FT DOMAIN 1..177
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 644 AA; 69840 MW; 08D5A9C7C13C4655 CRC64;
MRVIGTAGHV DHGKSTLVRA LTGIDPDRLQ EEKARGLTID LGFAWMDLPQ PDGSVESVGI
VDVPGHIDFI KNMLAGVGSI DAAVLVIAAD EGVMPQTREH LAILDLLAVP TGMVALTKVD
LVDDPEWLAL VELDVAELLQ ETRFAGAPIV PVSARTGAGL DELRQTLARL LGDLPPRRQR
GRPRLPVDRV FTLSGFGTIV TGTLSDGHLA VGDAVEILPP GISARIRGLQ SHRQPIQRAA
PGSRVAINLS GVSADAIHRG DVVVKPGTLE PTLLVDVSFR LLADAPKPLT HNQPVDFFSG
AAEVPARVRL LGTERLEPGQ QGWLQLRLAR PVVVAAGDRY ILRQPSPSMT LGGGQILNPH
PRRRWRRFDP AVLARFQTLA QGTPDEILLQ TLARFPLTPA AELFAHSGLD LAVAQETLAE
LQRSGAALAL DAGSEPVWLT PEAWEELVGR MARQVEHFHA QFPLRRGMPR GELRSRVLGQ
RDGGSLSVRI FNALIQRAQE QGLLEADDSV VWLPGFVPRP SPEQQARVDR LLAAFARAGM
SPPNPGDVLR LLGGDEPLLE MLIEQGQLVR LGGGVLFRRE EFEAAVAQVQ AFLQEQGTIT
LAQARDLLQT SRKYAQALLE EMDARRITRR EGDLRVLRAG LVDG
//
