ID A0A541C1E0_9PROT Unreviewed; 259 AA.
AC A0A541C1E0;
DT 16-OCT-2019, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2019, sequence version 1.
DT 02-APR-2025, entry version 17.
DE RecName: Full=Heme exporter protein C {ECO:0000256|ARBA:ARBA00016463, ECO:0000256|RuleBase:RU364092};
DE AltName: Full=Cytochrome c-type biogenesis protein {ECO:0000256|RuleBase:RU364092};
GN Name=ccmC {ECO:0000256|RuleBase:RU364092};
GN ORFNames=FK498_09180 {ECO:0000313|EMBL:TQF78444.1};
OS Elioraea sp. Yellowstone.
OC Bacteria; Pseudomonadati; Pseudomonadota; Alphaproteobacteria;
OC Acetobacterales; Elioraeaceae; Elioraea.
OX NCBI_TaxID=2592070 {ECO:0000313|EMBL:TQF78444.1, ECO:0000313|Proteomes:UP000315375};
RN [1] {ECO:0000313|EMBL:TQF78444.1, ECO:0000313|Proteomes:UP000315375}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=E_56292_2011 {ECO:0000313|Proteomes:UP000315375};
RA Robertson S., Ramaley R.F., Meyer T.E., Kyndt J.A.;
RT "Whole-genome sequence of a novel Elioraea species, isolated from a
RT Yellowstone National Park hot spring.";
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for the export of heme to the periplasm for the
CC biogenesis of c-type cytochromes. {ECO:0000256|ARBA:ARBA00002442,
CC ECO:0000256|RuleBase:RU364092}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|RuleBase:RU364092}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CcmC/CycZ/HelC family.
CC {ECO:0000256|ARBA:ARBA00005840, ECO:0000256|RuleBase:RU364092}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TQF78444.1}.
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DR EMBL; VIKA01000049; TQF78444.1; -; Genomic_DNA.
DR RefSeq; WP_141853794.1; NZ_VIKA01000049.1.
DR AlphaFoldDB; A0A541C1E0; -.
DR OrthoDB; 9778550at2; -.
DR Proteomes; UP000315375; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0015232; F:heme transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.
DR InterPro; IPR002541; Cyt_c_assembly.
DR InterPro; IPR003557; Cyt_c_biogenesis_CcmC.
DR InterPro; IPR045062; Cyt_c_biogenesis_CcsA/CcmC.
DR NCBIfam; TIGR01191; ccmC; 1.
DR PANTHER; PTHR30071:SF1; CYTOCHROME B_B6 PROTEIN-RELATED; 1.
DR PANTHER; PTHR30071; HEME EXPORTER PROTEIN C; 1.
DR Pfam; PF01578; Cytochrom_C_asm; 1.
DR PRINTS; PR01386; CCMCBIOGNSIS.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|RuleBase:RU364092};
KW Cell membrane {ECO:0000256|RuleBase:RU364092};
KW Cytochrome c-type biogenesis {ECO:0000256|ARBA:ARBA00022748,
KW ECO:0000256|RuleBase:RU364092};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364092};
KW Reference proteome {ECO:0000313|Proteomes:UP000315375};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364092};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364092}; Transport {ECO:0000256|RuleBase:RU364092}.
FT TRANSMEM 29..50
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364092"
FT TRANSMEM 70..91
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364092"
FT TRANSMEM 98..122
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364092"
FT TRANSMEM 134..156
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364092"
FT TRANSMEM 168..188
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364092"
FT TRANSMEM 208..229
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364092"
FT DOMAIN 15..191
FT /note="Cytochrome c assembly protein"
FT /evidence="ECO:0000259|Pfam:PF01578"
SQ SEQUENCE 259 AA; 28054 MW; EEFED94CD4629628 CRC64;
MDGNAAPRGS SLHRFANPGR FMRLSGAMLP WLAALAIAVS ALGLVWGLAF APRDWQQGDT
VRIMYVHVPA AWMAMGGYLG LAVASFVSLV WRHPLADIAA AAIAPVGAVF TAICLITGSL
WGKPMWGTWW VWDARLTSVL VLFFLYLGHI ALTAAFDEPD RAARPAAILA LIGAVNLPII
KFSVEWWNTL HQPASVTRLD APAIHMDILW PLLVAAAGFL FAFASLVLLR MRTAILERRA
RALMLARAAA ARLPEAMPA
//
