ID A0A543HG52_9MICO Unreviewed; 615 AA.
AC A0A543HG52;
DT 16-OCT-2019, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2019, sequence version 1.
DT 28-JAN-2026, entry version 26.
DE RecName: Full=Selenocysteine-specific elongation factor {ECO:0000256|ARBA:ARBA00015953};
DE AltName: Full=SelB translation factor {ECO:0000256|ARBA:ARBA00031615};
GN ORFNames=FBY41_4133 {ECO:0000313|EMBL:TQM57309.1};
OS Humibacillus xanthopallidus.
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Micrococcales;
OC Intrasporangiaceae; Humibacillus.
OX NCBI_TaxID=412689 {ECO:0000313|EMBL:TQM57309.1, ECO:0000313|Proteomes:UP000316747};
RN [1] {ECO:0000313|EMBL:TQM57309.1, ECO:0000313|Proteomes:UP000316747}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KV-663 {ECO:0000313|EMBL:TQM57309.1,
RC ECO:0000313|Proteomes:UP000316747};
RA Coleman-Derr D.;
RT "Genome sequencing of plant associated microbes to promote plant fitness in
RT Sorghum bicolor and Oryza sativa.";
RL Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Translation factor necessary for the incorporation of
CC selenocysteine into proteins. It probably replaces EF-Tu for the
CC insertion of selenocysteine directed by the UGA codon. SelB binds GTP
CC and GDP. {ECO:0000256|ARBA:ARBA00025526}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TQM57309.1}.
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DR EMBL; VFPM01000004; TQM57309.1; -; Genomic_DNA.
DR RefSeq; WP_141846642.1; NZ_VFPM01000004.1.
DR AlphaFoldDB; A0A543HG52; -.
DR OrthoDB; 9803139at2; -.
DR Proteomes; UP000316747; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR Gene3D; 1.10.10.2770; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00475; selB; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:TQM57309.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00023134};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000316747}.
FT DOMAIN 1..170
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 615 AA; 64584 MW; C52FD24FDD40B08B CRC64;
MHVIATAGHV DHGKSTLVRA LTGIEPDRWA EEHRRGMTID LGYAWTTLAP GVEVAFVDVP
GHERFIGNML AGLGPAPAVV LVVAADEGWR RQSAEHLAAV DALGITHGLL VVTRSDLADP
EPAMAQAVEQ LGRTSLAGSP ALAVSARTGQ GLGDLRAALG DLVATLPPPE TAGRTRLWVD
RSFSIRGSGT VVTGTLGAGT IRVGDDLLVH RASGATLRAT VRGLQSLEQP CDAVSAVARV
AVNLRGVRVD EVGRGDALLT PDAWHVTRTV DVRLTTDSSD ETSPGARHRP QEGDRLPAHL
MVHAGTLAVE ARVRPLGPGA VRLGLSDPLP LAAGDRVVLR DPGSRRVVGA LVVDADPPRL
DRRGAAARRA VEVAVLAAVP DLAREVARRG WMRHDDAVSL GIVVPAGGRP ASTVARRGGW
LVDDDAWQVA GQRLRAAVER RAESTPIDPG VPLEAARASA GLPDRALVTG LAEATGLEVR
DGRVGLPGHA AALGDRAEAA LRAVEARLRE HPFTAPEQHD LDAAGLGARE LAAAQGTGRI
LRLPGEIVLL PSAPALAMRE LARLPQPFTT SDARQALGST RRTVVPLLEH LDGRGWTRRL
DGSHREVVRA RPASP
//
