ID   A0A553HJI3_9PEZI        Unreviewed;       550 AA.
AC   A0A553HJI3;
DT   16-OCT-2019, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2019, sequence version 1.
DT   28-JAN-2026, entry version 23.
DE   RecName: Full=Glucanase {ECO:0000256|RuleBase:RU361164};
DE            EC=3.2.1.- {ECO:0000256|RuleBase:RU361164};
GN   ORFNames=FHL15_011009 {ECO:0000313|EMBL:TRX88111.1};
OS   Xylaria flabelliformis.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Xylariomycetidae; Xylariales; Xylariaceae; Xylaria.
OX   NCBI_TaxID=2512241 {ECO:0000313|EMBL:TRX88111.1, ECO:0000313|Proteomes:UP000319160};
RN   [1] {ECO:0000313|Proteomes:UP000319160}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=G536 {ECO:0000313|Proteomes:UP000319160};
RA   Mead M.E., Raja H.A., Steenwyk J.L., Knowles S.L., Oberlies N.H., Rokas A.;
RT   "Draft genome sequence of the griseofulvin-producing fungus Xylaria
RT   cubensis strain G536.";
RL   Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Endohydrolysis of (1->4)-beta-D-glucosidic linkages in
CC         cellulose, lichenin and cereal beta-D-glucans.; EC=3.2.1.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00000966};
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 7 (cellulase C) family.
CC       {ECO:0000256|ARBA:ARBA00006044, ECO:0000256|RuleBase:RU361164}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:TRX88111.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; VFLP01000100; TRX88111.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A553HJI3; -.
DR   STRING; 2512241.A0A553HJI3; -.
DR   OrthoDB; 412382at2759; -.
DR   Proteomes; UP000319160; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0008810; F:cellulase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030248; F:cellulose binding; IEA:InterPro.
DR   GO; GO:0030245; P:cellulose catabolic process; IEA:UniProtKB-KW.
DR   CDD; cd07999; GH7_CBH_EG; 1.
DR   Gene3D; 2.70.100.10; Glycoside hydrolase, family 7, domain; 1.
DR   InterPro; IPR000254; CBD.
DR   InterPro; IPR035971; CBD_sf.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR001722; Glyco_hydro_7.
DR   InterPro; IPR037019; Glyco_hydro_7_sf.
DR   PANTHER; PTHR33753; 1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE B; 1.
DR   PANTHER; PTHR33753:SF1; ENDO-BETA-1,4-GLUCANASE CELB; 1.
DR   Pfam; PF00734; CBM_1; 1.
DR   Pfam; PF00840; Glyco_hydro_7; 1.
DR   PRINTS; PR00734; GLHYDRLASE7.
DR   SMART; SM00236; fCBD; 1.
DR   SUPFAM; SSF57180; Cellulose-binding domain; 1.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR   PROSITE; PS51164; CBM1_2; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW   Cellulose degradation {ECO:0000256|ARBA:ARBA00023001,
KW   ECO:0000256|RuleBase:RU361164};
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361164};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361164};
KW   Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326,
KW   ECO:0000256|RuleBase:RU361164};
KW   Reference proteome {ECO:0000313|Proteomes:UP000319160};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          514..550
FT                   /note="CBM1"
FT                   /evidence="ECO:0000259|PROSITE:PS51164"
FT   REGION          479..517
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   550 AA;  58353 MW;  D39587803F24B6EF CRC64;
     MRTLGITNNW DSHVRDLAPV ALRLAGTMAP MSSSGLLGST RTWTGSDSRT TWAHSSFNHN
     LEYFNMAPSF RSVLATAVAL ASCQLANAQN PDTQADRKLN LVAHLEQREH PALTVYKCTT
     SGGCAAKPRS VVIDWNYHWF HTTDFLSCTT NSGVNTTLCP DEATCAKNCL VQGDSNYTSN
     GVTTSGDTLT MYQYTTDATG KTQNASPRLY LLGSDGNYEM LQLLGQELTF TVDLSTLPCG
     ENGALYLSEM DKSGGRNQYN TGGANFGSGY CDAQCPVQTW KNGTLNTNGS GYCCNEMDIL
     EANSRANAFT PHPCSSTDCD KGGCGFNPYA KGHTNYYGPG GTVDTSKPFT VVTQFNTNDG
     TTTGTLTSIT RKYLQNGKLV ASSEPAGDII TTDACNAADS SAAQFGGLTT MGQALGRGMV
     LTFSIWNDAS GFMNWLDSGS NGPCSATEGN PALIQQNNPK THVIFSNIRW GDIGSTFSSG
     SGSGTTTTTK ASTTKATSTT TKASATTTGS SPQPTQTQYG QCDGVGYTGP KVCASPYKCT
     KQNDYYSQCL
//