ID A0A562IH27_MICOL Unreviewed; 588 AA.
AC A0A562IH27;
DT 16-OCT-2019, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2019, sequence version 1.
DT 28-JAN-2026, entry version 26.
DE SubName: Full=Selenocysteine-specific elongation factor {ECO:0000313|EMBL:TWH70317.1};
GN ORFNames=JD77_05341 {ECO:0000313|EMBL:TWH70317.1};
OS Micromonospora olivasterospora.
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=1880 {ECO:0000313|EMBL:TWH70317.1, ECO:0000313|Proteomes:UP000319825};
RN [1] {ECO:0000313|EMBL:TWH70317.1, ECO:0000313|Proteomes:UP000319825}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43868 {ECO:0000313|EMBL:TWH70317.1,
RC ECO:0000313|Proteomes:UP000319825};
RA Klenk H.-P.;
RT "R&d 2014.";
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TWH70317.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; VLKE01000001; TWH70317.1; -; Genomic_DNA.
DR RefSeq; WP_145776625.1; NZ_BAAATQ010000139.1.
DR AlphaFoldDB; A0A562IH27; -.
DR OrthoDB; 9803139at2; -.
DR Proteomes; UP000319825; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00475; selB; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:TWH70317.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00023134};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000319825}.
FT DOMAIN 1..167
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 588 AA; 61856 MW; 3163F27F01C04D30 CRC64;
MWVVATAGHV DHGKSTLVRA LTGMEPDRWA EERRRGMTID LGFAWTALPS GGTVAFVDVP
GHERFVPNML AGVGPVPAAL LVVAADEGWM PQSAEHLAAL HALGVSYGLL AVTRADLADP
GPVLAQARDR IAATCLGAVE AVPVSAVTGA GLPELRAALD RLVARLPAPA LDAPVRLWVD
RAFTIRGSGT VVTGTLGGGR LAAGDQLELA DTGEPVRVRG LHRLGAARDR VDAVARVAVN
LRNVPRDRLR RGDALLTPGR FGRTDLLDVR IAGDAAADLP ATLTLHVGSA AVPARVRPLG
PDTARLRLAH PLPLLIGDRA LLRDPGRRHV SGGVTVLDVA PPPLDRRGAA AARARVLAGL
DGRPDLAGEL RRRALVRRDA LTRMGVPATA APVAGDWLAD PEHWRDLAAR LAAEAARYAA
AHPLEPGVPV DVLRHRLDLP DRALVEALVR PPLRLADGRV TASAQGALPA PVARAVARIR
AEYGGRPFQA PEAYRLAEIG LGPREIGAAV RAGALLRLAE NVVLLPGAVD DAARVLARLP
QPFTLSAARQ ALDTTRRVAV PLLELLDRRG VTRRLPDDAR TVVAPPGP
//
