ID A0A562VF85_9BACT Unreviewed; 674 AA.
AC A0A562VF85;
DT 16-OCT-2019, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2019, sequence version 1.
DT 28-JAN-2026, entry version 28.
DE RecName: Full=Selenocysteine-specific elongation factor {ECO:0000256|ARBA:ARBA00015953};
DE AltName: Full=SelB translation factor {ECO:0000256|ARBA:ARBA00031615};
GN ORFNames=JN12_03331 {ECO:0000313|EMBL:TWJ16576.1};
OS Geobacter argillaceus.
OC Bacteria; Pseudomonadati; Thermodesulfobacteriota; Desulfuromonadia;
OC Geobacterales; Geobacteraceae; Geobacter.
OX NCBI_TaxID=345631 {ECO:0000313|EMBL:TWJ16576.1, ECO:0000313|Proteomes:UP000319449};
RN [1] {ECO:0000313|EMBL:TWJ16576.1, ECO:0000313|Proteomes:UP000319449}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1139 {ECO:0000313|EMBL:TWJ16576.1,
RC ECO:0000313|Proteomes:UP000319449};
RA Goeker M.;
RT "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT (KMG-II): from individual species to whole genera.";
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Translation factor necessary for the incorporation of
CC selenocysteine into proteins. It probably replaces EF-Tu for the
CC insertion of selenocysteine directed by the UGA codon. SelB binds GTP
CC and GDP. {ECO:0000256|ARBA:ARBA00025526}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TWJ16576.1}.
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DR EMBL; VLLN01000026; TWJ16576.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A562VF85; -.
DR Proteomes; UP000319449; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR CDD; cd03696; SelB_II; 1.
DR CDD; cd15491; selB_III; 1.
DR FunFam; 3.40.50.300:FF:001064; Selenocysteine-specific translation elongation factor; 1.
DR Gene3D; 1.10.10.2770; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR015190; Elong_fac_SelB-wing-hlx_typ-2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR005225; Small_GTP-bd.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00475; selB; 1.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF09106; WHD_2nd_SelB; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 3.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:TWJ16576.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000319449}.
FT DOMAIN 40..213
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 674 AA; 73172 MW; 1696E023CA81D8FF CRC64;
MALLPDVQSI GKGALCGVLF LCYKGQPEYS FETVCGAPFM KHLILGTAGH IDHGKTSLVK
ALTGIDTDRL KEEKARGITI ELGFAHLELA DGTQFGIVDV PGHERFVRAM VAGVGGMDLV
MLVIAADEGV MPQTREHLEI CQLLGVKKGL VALTKSDMVD PDWLGLVAEE VREYLAGSFL
EGAAIVPVSS RTGAGLDDLR QELARLAAGV GQKRSDGPFR LPVDRVFTVA GFGTVVTGTL
LSGSIRVGDE VEILPGGLTS RVRGLQAHGA KAETGEAGQR LAVNLQGVEH TDLERGDVVV
PRELYRTTRA VDVRLNYLPS APRELRHRST LRLHSATYEV SAQVILFDRD TLQPGESALA
QLRLARPVLL LPGDPFVLRT YSPSATLGGG TVLDPAPPRR RRRTTEAMEL LTAIEEGDEG
DRIGRMVAAS LLSGLTVGEL TNRTGLSAKR LDAALTPLLS GGTVIQVVRE PRMFLGREAF
AALKESVLAE LDSYLQENAL KEGISKEELK TRLPKRSDPR FFTPVLASLE KEGTVVADRD
LVKLPGRKGT ATPEQTGLRE KIGSALLNGD SEPPTVKELC DLVQVPEKVL LEQLNSLVRE
GEVIRVKSDL YYAATPLAAI REKLFARLTE TGEITPNEFR EITGLSRKFM IPLLEYFDST
KLTIRVGDKR ILRK
//
