ID A0A5A8CQM4_CAFRO Unreviewed; 624 AA.
AC A0A5A8CQM4;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 08-OCT-2025, entry version 17.
DE RecName: Full=O-acyltransferase {ECO:0000256|PIRNR:PIRNR000439};
GN ORFNames=FNF29_01777 {ECO:0000313|EMBL:KAA0155402.1};
OS Cafeteria roenbergensis (Marine flagellate).
OC Eukaryota; Sar; Stramenopiles; Bigyra; Opalozoa; Bicosoecida;
OC Cafeteriaceae; Cafeteria.
OX NCBI_TaxID=33653 {ECO:0000313|EMBL:KAA0155402.1, ECO:0000313|Proteomes:UP000323011};
RN [1] {ECO:0000313|EMBL:KAA0155402.1, ECO:0000313|Proteomes:UP000323011}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BVI {ECO:0000313|EMBL:KAA0155402.1,
RC ECO:0000313|Proteomes:UP000323011};
RA Fischer M.G., Hackl T., Roman M.;
RT "Genomes of Cafeteria roenbergensis.";
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477, ECO:0000256|PIRNR:PIRNR000439}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004477,
CC ECO:0000256|PIRNR:PIRNR000439}.
CC -!- SIMILARITY: Belongs to the membrane-bound acyltransferase family.
CC Sterol o-acyltransferase subfamily. {ECO:0000256|ARBA:ARBA00009010,
CC ECO:0000256|PIRNR:PIRNR000439}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAA0155402.1}.
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DR EMBL; VLTN01000007; KAA0155402.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5A8CQM4; -.
DR Proteomes; UP000323011; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008374; F:O-acyltransferase activity; IEA:InterPro.
DR InterPro; IPR004299; MBOAT_fam.
DR InterPro; IPR014371; Oat_ACAT_DAG_ARE.
DR PANTHER; PTHR10408; STEROL O-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR10408:SF9; STEROL O-ACYLTRANSFERASE 2-RELATED; 1.
DR Pfam; PF03062; MBOAT; 1.
DR PIRSF; PIRSF000439; Oat_ACAT_DAG_ARE; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000256|PIRNR:PIRNR000439};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824,
KW ECO:0000256|PIRNR:PIRNR000439};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR000439};
KW Reference proteome {ECO:0000313|Proteomes:UP000323011};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PIRNR:PIRNR000439};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 25..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 97..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 207..226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 413..435
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 455..481
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 548..568
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 588..606
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 256..370
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 260..288
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 321..333
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 340..351
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 546
FT /evidence="ECO:0000256|PIRSR:PIRSR000439-1"
SQ SEQUENCE 624 AA; 67073 MW; F69E3E9E5CD08A24 CRC64;
MSGNDLVATL EQLGLGVLVD TNAGLLMPAL AVLALLGVVY FSALACMGDA MPRQPRARTK
REVLRNADSI LDSGGFSMLP WLDSMHDVSG TGAADGWFMA LAAIVIYWIL GTIVVNVERS
GSPFSDDGVF WWRLVSGLWS LGLAFLAFAA VFSLAFVFQS AVVIAGVRPP MAVQIAFQVV
LENGMLAAAV WYAYYGDAKD WPWTQKAGLL LEVAVLVLKA HSYLAVNGAL SRGSLAGFAA
SSTALDAMVE LEGGAEEADA AARAERSAVE ARQRATRDQH DGDSHADDGT SSDSEEEDAR
QGGSGHNTRS SSTRRRRRRP AAAAAATESP ASPVTRRSAA KAAKAADQAT ASPHDDSSAP
RLTQTPSHGA DISYPDNVTL ADFVRFACAP TVVYSPNFPS TAAFRPLYLL EKVVFAAILL
FAALETAIQF VLPVVADLGR AHAAGSPLPA GLVMARMVVP LTALMLLLFF LVFDVLFNAF
AEFTLFGDRR FYGDWWNSTS FAEFSRKWNR PVHTWLLHHV YLPLQEAGLG SAVARYGTFA
VSIAAHELLL HGFFGFAAPW LLVFSLFQFP LFTIMRLPIF KGKRLGNLVF WFGMALGVPL
VGSLYLNDFC KSEPGSCIMT PAAA
//
