ID A0A5A9NB72_9TELE Unreviewed; 865 AA.
AC A0A5A9NB72;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 18-JUN-2025, entry version 20.
DE SubName: Full=RFX1 Regulatory factor X 1 Transcription factor {ECO:0000313|EMBL:KAA0706029.1};
GN ORFNames=E1301_Tti016872 {ECO:0000313|EMBL:KAA0706029.1};
OS Triplophysa tibetana.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Nemacheilidae; Triplophysa.
OX NCBI_TaxID=1572043 {ECO:0000313|EMBL:KAA0706029.1, ECO:0000313|Proteomes:UP000324632};
RN [1] {ECO:0000313|EMBL:KAA0706029.1, ECO:0000313|Proteomes:UP000324632}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TTIB1903HZAU {ECO:0000313|EMBL:KAA0706029.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:KAA0706029.1};
RX PubMed=30977968;
RA Yang X., Liu H., Ma Z., Zou Y., Zou M., Mao Y., Li X., Wang H., Chen T.,
RA Wang W., Yang R.;
RT "Chromosome-level genome assembly of Triplophysa tibetana, a fish adapted
RT to the harsh high-altitude environment of the Tibetan Plateau.";
RL Mol. Ecol. Resour. 19:1027-1036(2019).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAA0706029.1}.
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DR EMBL; SOYY01000021; KAA0706029.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5A9NB72; -.
DR Proteomes; UP000324632; Chromosome 21.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:TreeGrafter.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR FunFam; 1.10.10.10:FF:000017; transcription factor RFX3 isoform X1; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003150; DNA-bd_RFX.
DR InterPro; IPR039779; RFX-like.
DR InterPro; IPR007668; RFX1_trans_act.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR12619:SF23; MHC CLASS II REGULATORY FACTOR RFX1; 1.
DR PANTHER; PTHR12619; RFX TRANSCRIPTION FACTOR FAMILY; 1.
DR Pfam; PF25340; BCD_RFX; 1.
DR Pfam; PF04589; RFX1_trans_act; 1.
DR Pfam; PF02257; RFX_DNA_binding; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51526; RFX_DBD; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000324632};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 323..398
FT /note="RFX-type winged-helix"
FT /evidence="ECO:0000259|PROSITE:PS51526"
FT REGION 1..63
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 286..316
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 433..454
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 804..865
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..25
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 32..44
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..63
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 294..309
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 439..454
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 811..827
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 865 AA; 94789 MW; D0223AB2E83CE503 CRC64;
MNFIRTGPSA APPAAQTSPP LTQAQKSQAI VQTPPTQAPP TQTQYVTAEI QSSPTQSSNA
QNTPQYIVVT VTEGSLHSSD SVSDSSPPSA VVQTGVPTQV VQQVQTAQQR SVVQSTTLPT
KTEPGTQLNV TSLQSVHLTQ EVQQQLQQVP VQHVYTNQVQ YVEGGDNNYT TSTIRSSSFP
YTETPLYTQT TAGQYYETTP ASASEATSPG TPLTVSVTTG SPGLSMFVTE AGQIVANPTA
TAGGGVTAVV ATAGPASNGS GDSGSEANGS RASYVIQGGY MLAGGGSGSS SSGNGYTHPT
RASPTTVSIN EGEDNSVPSA DKKVQWLLDN YETAEGVSLP RSTLYCHYLL HCQEQKLEPV
NAASFGKLIR SVFMGLRTRR LGTRGNSKYH YYGLRIKASS SLIRLMEDQQ HLAMRQQPFS
QKQRLKPVQK VEGITNGMSS GSGQQQQQQS SGLSDISTQV QQYQQFLDAS RALPEFPDVD
LQGKALPEGI ELEHLKGFQL LYREHCEAIL DVMVNLQFPL VETLWKTFWR FSENLAGDAA
LAVHDESEKR LPKSCLVLLC KYDPVLRWSR DCDNTLYQGL VEMLIPDVLR PIPSALTQAI
RNFAKSLESW LTNAMMNIPE EMVRVKVTSA SAFAQTLRRY TSLNHLAQAA RAVLQNTAQI
SQMLSDLNRV DFANVQEQAS WVCRCEDRVV QRLEQDFKLT LQQQNSLEQW AAWLDGVVSQ
VLKPYQSSTA FPKAAKLFLL KWSFYSSMVI RDLTLRSAAS FGSFHLIRLL YDEYMYYLIE
HRVAQAKGET PIAVMGEFAS LGRSLNPLDP DKDDEEEEEE DSEDECQELS LQSDCGTIGD
ESLEPPAKLA RTDQRVLFST GSMDN
//
