ID A0A5A9PJ54_9TELE Unreviewed; 405 AA.
AC A0A5A9PJ54;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 05-FEB-2025, entry version 16.
DE SubName: Full=Failed axon connections-like protein {ECO:0000313|EMBL:KAA0720717.1};
GN ORFNames=E1301_Tti011530 {ECO:0000313|EMBL:KAA0720717.1};
OS Triplophysa tibetana.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Nemacheilidae; Triplophysa.
OX NCBI_TaxID=1572043 {ECO:0000313|EMBL:KAA0720717.1, ECO:0000313|Proteomes:UP000324632};
RN [1] {ECO:0000313|EMBL:KAA0720717.1, ECO:0000313|Proteomes:UP000324632}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TTIB1903HZAU {ECO:0000313|EMBL:KAA0720717.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:KAA0720717.1};
RX PubMed=30977968;
RA Yang X., Liu H., Ma Z., Zou Y., Zou M., Mao Y., Li X., Wang H., Chen T.,
RA Wang W., Yang R.;
RT "Chromosome-level genome assembly of Triplophysa tibetana, a fish adapted
RT to the harsh high-altitude environment of the Tibetan Plateau.";
RL Mol. Ecol. Resour. 19:1027-1036(2019).
CC -!- SIMILARITY: Belongs to the FAX family. {ECO:0000256|ARBA:ARBA00006475}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAA0720717.1}.
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DR EMBL; SOYY01000005; KAA0720717.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5A9PJ54; -.
DR OrthoDB; 5809458at2759; -.
DR Proteomes; UP000324632; Chromosome 5.
DR GO; GO:0005737; C:cytoplasm; IEA:TreeGrafter.
DR CDD; cd03193; GST_C_Metaxin; 1.
DR CDD; cd03080; GST_N_Metaxin_like; 1.
DR Gene3D; 1.20.1050.10; -; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR026928; FAX/IsoI-like.
DR InterPro; IPR045796; FAXC_N.
DR InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR InterPro; IPR040079; Glutathione_S-Trfase.
DR InterPro; IPR033468; Metaxin_GST.
DR InterPro; IPR050931; Mito_Protein_Transport_Metaxin.
DR InterPro; IPR012336; Thioredoxin-like_fold.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR12289:SF76; FAILED AXON CONNECTIONS HOMOLOG; 1.
DR PANTHER; PTHR12289; METAXIN RELATED; 1.
DR Pfam; PF19333; FAXC_N; 1.
DR Pfam; PF17171; GST_C_6; 1.
DR Pfam; PF17172; GST_N_4; 1.
DR SFLD; SFLDS00019; Glutathione_Transferase_(cytos; 1.
DR SFLD; SFLDG01200; SUF1.1; 1.
DR SUPFAM; SSF47616; GST C-terminal domain-like; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000324632}.
FT DOMAIN 1..104
FT /note="Failed axon connections homolog N-terminal"
FT /evidence="ECO:0000259|Pfam:PF19333"
FT DOMAIN 115..208
FT /note="Thioredoxin-like fold"
FT /evidence="ECO:0000259|Pfam:PF17172"
FT DOMAIN 260..322
FT /note="Metaxin glutathione S-transferase"
FT /evidence="ECO:0000259|Pfam:PF17171"
FT REGION 367..405
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 405 AA; 46243 MW; F23B966F3120634F CRC64;
MYWRVGFAWT RSCVLELARN KSFTLDFCGS EGPLSLYGYI IAHPLQEYGG IMSALASDTW
WRKTLYITGG ALLAAAAYLL HELLVIRKEQ ELDPQDAIIL HQFARPKTGV PSLSPFCLKI
ETYLRMADLP YQNYFDGRLS PQGKMPWIAY NQEQVYGTEF IINFVEEKLG VNLNSSLSPE
EKAISRAITK MVEEHFYWTI AYCQWVDNVE ETQKMLSTNG PLSDLLKWIV SQVTGGIVKR
EMYGHGIGRF SKEEVYTLME KDMRTLATLL GDKKYLMGPQ FSTVDASVFG HLAQAMWTLP
GTRPEQLIKG EFINLAMYCE RIRRKFWPEW FVDVDDLYYD GLSDEPVSPS LLADLGLYSH
SDSFQELESL PSHRDTQTPD SDVTGRSLFD SDMDTEVSET EHLKG
//
