ID A0A5B1CH38_9BACT Unreviewed; 6494 AA.
AC A0A5B1CH38;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 02-APR-2025, entry version 17.
DE SubName: Full=Matrixin {ECO:0000313|EMBL:KAA1258524.1};
GN ORFNames=LF1_10440 {ECO:0000313|EMBL:KAA1258524.1};
OS Rubripirellula obstinata.
OC Bacteria; Pseudomonadati; Planctomycetota; Planctomycetia; Pirellulales;
OC Pirellulaceae; Rubripirellula.
OX NCBI_TaxID=406547 {ECO:0000313|EMBL:KAA1258524.1, ECO:0000313|Proteomes:UP000322699};
RN [1] {ECO:0000313|EMBL:KAA1258524.1, ECO:0000313|Proteomes:UP000322699}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LF1 {ECO:0000313|EMBL:KAA1258524.1,
RC ECO:0000313|Proteomes:UP000322699};
RA Wiegand S., Jogler M., Boedeker C., Pinto D., Vollmers J., Rivas-Marin E.,
RA Kohn T., Peeters S.H., Heuer A., Rast P., Oberbeckmann S., Bunk B.,
RA Jeske O., Meyerdierks A., Storesund J.E., Kallscheuer N., Luecker S.,
RA Lage O.M., Pohl T., Merkel B.J., Hornburger P., Mueller R.-W., Bruemmer F.,
RA Labrenz M., Spormann A.M., Op Den Camp H., Overmann J., Amann R.,
RA Jetten M.S.M., Mascher T., Medema M.H., Devos D.P., Kaster A.-K.,
RA Ovreas L., Rohde M., Galperin M.Y., Jogler C.;
RT "Deep-cultivation of Planctomycetes and their phenomic and genomic
RT characterization uncovers novel biology.";
RL Submitted (AUG-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAA1258524.1}.
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DR EMBL; VRLW01000001; KAA1258524.1; -; Genomic_DNA.
DR RefSeq; WP_068265225.1; NZ_LWSK01000080.1.
DR OrthoDB; 247526at2; -.
DR Proteomes; UP000322699; Unassembled WGS sequence.
DR GO; GO:0031012; C:extracellular matrix; IEA:InterPro.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0030574; P:collagen catabolic process; IEA:TreeGrafter.
DR GO; GO:0030198; P:extracellular matrix organization; IEA:TreeGrafter.
DR GO; GO:0000272; P:polysaccharide catabolic process; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.380; -; 3.
DR Gene3D; 2.60.40.2810; -; 1.
DR Gene3D; 2.60.40.3440; -; 2.
DR Gene3D; 3.40.390.10; Collagenase (Catalytic Domain); 2.
DR Gene3D; 2.160.20.10; Single-stranded right-handed beta-helix, Pectin lyase-like; 1.
DR InterPro; IPR002105; Dockerin_1_rpt.
DR InterPro; IPR045474; GEVED.
DR InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR InterPro; IPR006626; PbH1.
DR InterPro; IPR012334; Pectin_lyas_fold.
DR InterPro; IPR011050; Pectin_lyase_fold/virulence.
DR InterPro; IPR001818; Pept_M10_metallopeptidase.
DR InterPro; IPR006026; Peptidase_Metallo.
DR InterPro; IPR010221; VCBS_dom.
DR NCBIfam; NF012211; tand_rpt_95; 3.
DR NCBIfam; TIGR01965; VCBS_repeat; 1.
DR PANTHER; PTHR10201; MATRIX METALLOPROTEINASE; 1.
DR PANTHER; PTHR10201:SF323; MATRIX METALLOPROTEINASE-21; 1.
DR Pfam; PF17963; Big_9; 4.
DR Pfam; PF00404; Dockerin_1; 1.
DR Pfam; PF20009; GEVED; 1.
DR Pfam; PF00413; Peptidase_M10; 2.
DR SMART; SM00710; PbH1; 9.
DR SMART; SM00235; ZnMc; 1.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 2.
DR SUPFAM; SSF51126; Pectin lyase-like; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000322699};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 827..979
FT /note="Peptidase metallopeptidase"
FT /evidence="ECO:0000259|SMART:SM00235"
FT REGION 1..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1068..1091
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1949..1975
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2267..2286
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2901..2929
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1068..1080
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2914..2924
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 6494 AA; 677420 MW; E19F70B8B79B7CEC CRC64;
MAFFRLSKKS DRFSQNHTTD NSSPKRKRKT LRSSKISMDR QSKVETLERR ELLAAEILNA
DIVPHGLFAE GTPQSIIDAW EAKAHANQAG HHDLDGPQPI LSGTRWRTSA LGTSPDEGDP
IGLTWSIVPD GTDIIDPQTG GVEGTSNLVG FLDNIYGGAA IDVIANKPWF ELFERVYDSW
ADTTGLSFQY EPFDDGAPMA AGPSVGVLGV RGDMRVSGRA IDGPGNVLAF NYIPSNGGNG
GADGDMVVDT SDTFYARNSD GPTGRNTGLH NVLAHEVGHG LGFLHVVPVN GTKLMEPIIN
LGFYGPQEDD LYNAHALYGD RLESNNSIDQ PFDLGPLRNE VAEFTDLSIS NNLDVDVFRF
DVAIPTFISG SVQPTGTEYL EEGQFGDPAS TLVNRAAESD LGIRVLDADG NVLQAINNTG
LGSPESLPEV ELATAGTYFV EVFGAGDTQL YDLALRVGRP FGFDPQSGDL RLISVNPSAE
DLFSPDDVNV LQTSPSELTL RFTSDSAIDE ASLAGGIRIS GAGADQLRGT PDDVVITPGW
IGFGENEQTI VARFAEPLAD SRYRIEVFGA DIESEGVTAL RESDGGLFVP RVNGTDRDAI
DFELELGARV ISVVPQPVTR NSAGVLTPQR ETIHVYFDDN DLFASFDPAD PGTDSLVNPA
FYQLIRTEDS VENTDDQLHL PISVRAVEFE TQTVPDPVNP GATIDVQVRV NRVELTFLDD
LDDLTGGGAY RLKIGSSEPV TVAGDPDDIA TQSELADIGE LASTAEVLNF AGGTTVIASG
EIVSDGLPFD FPGASPLEPG HRNIAEERHL NAIDETGRLT THYYNFALNR PFLVTDGVEY
FTSINPQQMQ RARESFALWG RRTGIQFVET DSAVPPDGSS PNTTFVVGDF AAVGSVSEPG
GTIGLGGPAQ VTMDAAETWF DGYGPSTGLG QSFFITALHE IGHAIGLGHA YELQPSTVMG
GADFFPRDTE TNFPGVIDRL HANVIHRPDN RDVDMYRFNV PDGVGGTIDI EAFAQRTTGG
SLLDTHIALF RDDGGTITRI AANNDSFGTD SALRLELGSG DYLIGVTANG NQDYDPQQPG
SGTGGDSEGS YDLRVSFRET ETSTIRDAAG TAFDGDADGT PGGAFNYFFR VAAESDTLYV
DASAADPPAG TAGSALTPFN EIDQAIAAAT PGQTVRIVGN AGADGIIGLE QDNFSAAADN
FAYEIGRIDS INTTLDDGRN LIVPAGVNVV IDAGAILKMF NSRIAVGSVP GGVDASGGSL
QVLGVPHLPV FITSHNDTSI GLEDGNLGLA PSPGDYGGID IRSGIDRAEG RFDAEREGLF
LNNIFQTDIR YGGAVVPING QLVAVDPIRL DSARPTLIGN RITRNSGAAV SADPASFEET
RFTGLRSQRD ASFVPDYDRV GPVIYGQHMV DNSVNGLLIR IDTAAGSTPE ELLVSARFDD
TEIVHVLGDN LLIRGNPAGA MTQSPATAPV LTNLSAVSVA GVSGLAAGSY QYHISFVDDN
GFETPPSLPT TSVTVVDGQS VQLNGLPVAT GDFSSRRLYR VNPNGSVGLV AELDRSDTTH
VDSSADIGTA PLTLSPEAVR TRLDARLQVD PGVTIKSDDV RIELGFGADL IAEGTDVRPV
VFTSRSDDRY GAGGTFDTTG NGETSGAPGQ WAGIYARPDA SLSIDQAVIA YAGGTSTVEQ
TTASFNAIEI RQADARIAHT LFESNAGGDS ESNNNRNRGT RLENSSAVIY VAGAQPIIVE
NTFVGTVSAG GNSTAAIDIN TNALTDTPLN DLGRQTGDID LVEHPINVGP LIRGNRLAEG
ITYTAGLHIR PEIVATGVVF DDTDITHVVS GSIVDPNLHT FGGLQLRSRG GESLVVKFDT
TDGSLQADGA PLEIEDRIGG TLQVLGQPGF PVVLTSIHDD SVGAGLTPDG LSLTNTGGDS
DPIAGDYEGL LISHFANDRN VAAIVENESS GGAEGDPNSN PDRAQSLGRL ASGEKSSDEN
LRLGFVVDGA IQFPGDQDVY SFVGTAGTTV WLDIDRTDET LDSVIEIIDA SGNVLAASDN
STEEIADGAI SNPGSIGGLT LSQDPLTPRH SINDAYRDLY TLNTLDAGMR VQLPGAAGSA
EQYFVRVSGA NGSFGIYELQ VRLRELDEFA GSTVRYADIR YASTGINLEG GPAHSPLVGE
LRDNGNDATV DLGSLATTER AVISIAGELE DAIDERTYQF SISRAGLQTG TTTASGITEP
GDYIATTFDI DYADGLGRPD TTILLYSRDV EANTRTLIAV ANDSNISSDR RDTTESGSDL
DDLSRGSVGS RDGFLGSMEL LAGDYEVVVT GNAQVPTQLL QSLIPSPTNP NIRLEPLGNI
ARIAEDRFDG PGGDNDDIPR NTVDTTGFLG NSPVQVVLQG EENAIPFSLG DVTLFVIEGS
RPNNSARVGS IDPQVGVRDA LYTTDQNPLG DIAQSPDGFV YASSAGTRNT ENVNDANAGN
FFRLNEDGQT VESVGNTGLL TFEGFVNNGN NAVGRQQSVA GGRIGNGHVM SALTYQVSGA
NRQNLALFGV SSLGNGRDTY TSVTVGGANG NVNGLVPDTP ATNFLWRLNP ETGAAISAAP
GGQERQGDSR AQGAGTAQIE IGRIETSPGA IVTGIADVDG TLFAVTTLGE LISIAGITHN
TNNPGAGNTP ASNRNLPENL IGAPVATIID PVTDQPVVFT SLDAGPRNIT DPTSGLPLSN
FLFATDDAGQ MYVFDTSGVL QPLLQRGLSQ QQTQAVDPVG IAFSNLDVNL FHRTVERGGD
AGHGAPATHD QTRMDAEAGQ TSLFFGYELP GGPDDNTQLG DWEGQFASDR ALKPIPNMPN
NRRPSYDFAG GAHGNIESFG FDLADYGADD EPTLYFNYFL DTEDAEGNIN GGQSRDSVRV
FVASEERQTW TLVATNNSRN AGTLADTGGG NFDEFDRGES RYTQDENGEG EAYQTRELFD
AAQWRQARVP LQPWAGDNDV RIRIEFNSAG ESERNVAELR AVDARVLLEG IAGAEPNRSF
MITEDDLAGT FGGATTTTFE FDFGLVLRTA AGSSITNGDS FTLAPTNGAA PTTFTFLQLD
GSSPVSFDAL DTAADVGVEL VAAIEAAGLT VTPDAVDPEF LDITDADGNV VTVASNNAAI
IDGVRVELID GASLASGDTL TLTVADPEID PITLVFASST DIPYEATDTA GAVAASAATV
LENAGYTSVI DSSNTSRIQI TASDALAVTT AVGNDTTIAS SVADLTDGTI ITPVPGTDLI
EGDTLEITDS VSLETTTFVF RDNDVLAVEF DGATIADTVD DAETVAANLV GGFVAGDLLA
EVDLVDASVF GFVDADGNSV QVALASNNLS AVQSLISVSD AAQLSEGDLL TLTPSLGGAP
IVFRYTDTAN LNVVFDPAGT DADAVSDLVD AINLQIPGAA TIGTGDGTTV VISDPAVDDF
QLVDPTGVLL TDVLTLGDGA SIANGDTFTL NSVAGPTTFT FRDVAPDPLL DTDIVYDPAS
GAGAVATAVS DAINAAGFTA TANAVSASSI TVVDGDGNPV FLDAETTTVN LGGFLLNAVP
VGGEEITLSS GAGDQTLVFQ PGTEILIPFT VGDDAATIAA ATAAAIDATV ELSASVDLGD
ANRVELSDAD GTLISAVASD NVLLTTSFRA VDGAGLVDGD TITVTLPPVV PADPDLPPVP
APLPVTIVLR DTDINSVFFN ATDTSGEVGV AIGQALLAAG FTMTVAASEN ALTPTEVSLI
SGGVAVVDAF GVDPSSVRIP IGINDVATDV QLAMQMAIAD EFTADDAVAN LNQFPLARQS
VRLFGFTIND PGSLGYFQNP TNIIPAAEPD TDNPLTGLFV DAITGLPVAT PHPGLDSGVY
PELNETGFGN SLADSLRTSG RRASNNTSEG FYLDDLIIGF AERGELVHDA TPGNQLSLNP
LHEQEINIGG RVTDLPDQGA FQLEVRLSVD TVAPIGGTDS ERIRNFDTND IIGRGLSFDF
VRTNGADISD GAVITLSDGN DIARFEFDNL DDGVGSGVAT GAIPVSFTSD MTSIEIATVV
RDAINSPAAQ SILDITAFSP DGSTTTGVGT SDTFLLSGLV SSDLTGGLDF APAIPTLFSF
VFGTEFENAG TATGDENRFR DQGQIIIENT FISSSSSFGI ESTFERANQA DTPLDIGATQ
PLPGATRAFP TPNPQNLVPG PVLRNNVLFN NTGGGIRVSG DTSNGNLPAA APFVRVINNT
IVDNGFGIAI STGAAPTLLN NAVVGNTVGI FADNSVNAAE IFNTLYGDNG TNVFGVGLGG
VPQIAGGDQV FVDRTGDNFY PSIGSQLIDN GNAAQGDRLG LRTLRGSLGI AESPILAPAT
DITGFTRADD GDPATGGGVG SSVFIDIGAF DRVDRVGPSA RLITPLDNDA LGADQDGLPT
IVQLSSGTLD EFVIRLEDIR GAGIDDSTVG PDRITVTQDG RVLASGVDYT FAYSATDNTI
ILTPTSGIWT PGSAYEITLS NRDRTGLQLQ SGDQIDDGET FSIIDNDGTE VEFEFDGGLA
FRFNDVANDG DIIRFTSGPT IQIEFDIDGD LDPATTDVIA IDPADNAESL SVKLANLLRN
GDFGFDTAVS LNGDLASITF DPDVDAEVVS TTVEVASRAG VADGSVAVPY LPTADFSAES
TAGSLIAAIS NSDLNASAFT PGGGQVFVDN VASVTNLVSA DVGAIVDLAG NDLQANRVNR
ETQFTILLPG TQLDFGDADT SFPTLVADNG ARHTIAAGAP RFGTFIDSEL NSRRLNGGTD
DAGLVVVGNG TGGLTVTTID DGIELVVDTT VRPGDTVTID LGGGELRVFE LVLAGNAPTN
PANVPVLLVP NSVGVSASAL AVRTAERLAS VITENLSQSV GGALPPATSV QYVRETERLQ
VVSVDDEDGV LIFGSGSFAG MFIDPEFDSM GGTVAASEEV LNFLNPNATN GVFLALDVQG
NGLVDAWIDF NDDDDFDDVG EQVLFNQPVI DGDSNRVQII TPANVSLPSG GSKEVAARFR
ISSTGNQTPD GLTIGGEVED YTVTIIDAPL PQAVSASYTI NEDNIGNDPL DTTAFPLQYP
PLTTDTSAFT NVRYVVARDT TFGTLNLTDT GEFTYQPRED FFGTDTFTYQ VIGNVNVDGT
ILPVRSELAT VAITVNPVND APSALVQVIQ GIEDQDLSFT ADDLLDGALP QDDADVRISP
FDEQEQTLSV ININVLDETG VMVPVLDLTD PTDPFSISEG SVQREVYIEV TAGVFEPFGT
LTVDVATDSV TGVTEVSELT FAPEIQVDSG ELDVDGNPIF DVVRLDNYNR TSPAPVPFEY
VVADNGQTTL PDGTDATESV TPEIITQTAT IELLERNDAP VAGNDVIIAV EDPVGGFVID
HAMILGNDTA GAKADAEGRN ASIDENNGTT DITLSMPVLI DNPAFASPDP TVSVFTSGFG
VVSYNPADPT QFIYTPRPDF YGIDSFVYSI TDNGNNVSLD GSGAEINTPS MLTTTATVVL
DVRPQNDAPF TPNKPTAAQA LTGVFTTTED PATPLIITAN SLTEGSFGHA APAFFGAPQN
ESNQTFFVSG VFDKDDNEIT IAEVGDPADP DTFESPSGTF RPFFNATAGP LFGHLIRVEY
TPADDFNSAQ DLGAGLVSVP DTFAFTLSDD GISIDQRPSV DLNGNPFGDY PIEPASIKAT
VAITVTPVND APALGDDTVD AVEDVQLLIP FATISANDSV GPADEVDGTN DGVLTYSQSP
ITTTAGGIVN FLANGDLSYT PPAEFSGEDT FVYSATDQGV TVGGDGNRAS DPRSSTGTVT
VNVAALNDPP TIDQIEDLTL LEGEVGRVAT ISGISAGGGE NQMLRVTATS SAPSPFDALT
PVYTSPNEVA TIPLTPRPFE SGTTVVTVTV TDAGFDGIFD TADDASTSLD INVNVLEVND
APTIDAIDDF SVTENDTVLP VDLTGISAGP QETQPLAITV TSSNQSLVRN EDIVVDYTDP
DTTGSFTYSL LPDRAGTTTL TVTLTDGGLD GDLATAGDNG VTTETITLSV INIVNIPEPA
DDAFDSDEDL AVIIDSDQLT DNDFAPDLAP GESLSVILDA DNPDDATQTI TTTLGATVTL
NTATGELTYD PVTATQLQAL APGEFVEDSF TYFVNDGTLS APLPSATVRM SIEGINDAPT
VVDDVIGSPP LPANPSTLAP LLVRPLANDS DVDGTLDINS LIVTEEPLFG SVSRRLVDDG
NGNQVVELAY SPFVQFAGTD SFKYTVSDDL GQQSVEATIE IRPSMAPVTG PDIGGGVAAD
GITINVLAND VPVVGSLDLS SLMISRAANN GVATANSDGT VGYVPNPGFV GTDSFQYTVA
DSEGNVSEPV TVVVNATANG MQNPVRFADV DANGRVEAFD ALLIINRLDR ASSNRVPVDS
ADRGPNFFDV NGSGDITAFD ALMVINNIGR PAPIFEGESI QEPTLVAPST SLPSVALPNQ
SDDRLDAPVG LAIDPGLQVS KQVSTDSVAP GQNTPSGDVV DDSLVDLLAQ DAGSEAFDEI
SEESATDLAF KLLR
//
