ID A0A5B7YG83_9ALTE Unreviewed; 324 AA.
AC A0A5B7YG83;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 18-JUN-2025, entry version 23.
DE SubName: Full=Integron integrase {ECO:0000313|EMBL:QCZ94667.1};
GN ORFNames=FBQ74_14855 {ECO:0000313|EMBL:QCZ94667.1};
OS Salinimonas iocasae.
OC Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
OC Alteromonadales; Alteromonadaceae; Alteromonas/Salinimonas group;
OC Salinimonas.
OX NCBI_TaxID=2572577 {ECO:0000313|EMBL:QCZ94667.1, ECO:0000313|Proteomes:UP000304912};
RN [1] {ECO:0000313|EMBL:QCZ94667.1, ECO:0000313|Proteomes:UP000304912}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KX18D6 {ECO:0000313|EMBL:QCZ94667.1,
RC ECO:0000313|Proteomes:UP000304912};
RA Zhang H., Wang H., Li C.;
RT "Salinimonas iocasae sp. nov., a halophilic bacterium isolated from the
RT outer tube casing of tubeworms in Okinawa Trough.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Site-specific tyrosine recombinase, which acts by catalyzing
CC the cutting and rejoining of the recombining DNA molecules. The XerC-
CC XerD complex is essential to convert dimers of the bacterial chromosome
CC into monomers to permit their segregation at cell division. It also
CC contributes to the segregational stability of plasmids.
CC {ECO:0000256|ARBA:ARBA00037721}.
CC -!- SUBUNIT: Forms a cyclic heterotetrameric complex composed of two
CC molecules of XerC and two molecules of XerD.
CC {ECO:0000256|ARBA:ARBA00038613}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the 'phage' integrase family.
CC {ECO:0000256|ARBA:ARBA00008857}.
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DR EMBL; CP039852; QCZ94667.1; -; Genomic_DNA.
DR RefSeq; WP_139757403.1; NZ_CP039852.1.
DR AlphaFoldDB; A0A5B7YG83; -.
DR KEGG; salk:FBQ74_14855; -.
DR OrthoDB; 9801717at2; -.
DR Proteomes; UP000304912; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR FunFam; 1.10.443.10:FF:000007; Tyrosine recombinase XerC; 1.
DR Gene3D; 1.10.150.130; -; 1.
DR Gene3D; 1.10.443.10; Intergrase catalytic core; 1.
DR InterPro; IPR044068; CB.
DR InterPro; IPR011010; DNA_brk_join_enz.
DR InterPro; IPR013762; Integrase-like_cat_sf.
DR InterPro; IPR002104; Integrase_catalytic.
DR InterPro; IPR011946; Integrase_integron-type.
DR InterPro; IPR010998; Integrase_recombinase_N.
DR InterPro; IPR004107; Integrase_SAM-like_N.
DR InterPro; IPR050090; Tyrosine_recombinase_XerCD.
DR NCBIfam; TIGR02249; integrase_gron; 1.
DR PANTHER; PTHR30349; PHAGE INTEGRASE-RELATED; 1.
DR PANTHER; PTHR30349:SF64; PROPHAGE INTEGRASE INTD-RELATED; 1.
DR Pfam; PF13495; Phage_int_SAM_4; 1.
DR Pfam; PF00589; Phage_integrase; 1.
DR SUPFAM; SSF56349; DNA breaking-rejoining enzymes; 1.
DR PROSITE; PS51900; CB; 1.
DR PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE 3: Inferred from homology;
KW DNA integration {ECO:0000256|ARBA:ARBA00022908};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU01248}; Reference proteome {ECO:0000313|Proteomes:UP000304912}.
FT DOMAIN 1..83
FT /note="Core-binding (CB)"
FT /evidence="ECO:0000259|PROSITE:PS51900"
FT DOMAIN 101..315
FT /note="Tyr recombinase"
FT /evidence="ECO:0000259|PROSITE:PS51898"
SQ SEQUENCE 324 AA; 37554 MW; AD465F8B69101A4D CRC64;
MKSQFIRDVS NFMMMKRYAK RTIRTYLIWI ADYIRFHNYS HPSKLDSSHI EAYLTQLAVR
RNLSASTQAT ALNALVFLYQ KYLKIDIAKD LDFVNSSRPR KLPVVLTVEE MNRLLGMVSE
RHFLPVAMLY GSGLRLMECV RLRVKDIDFD FKCVRIWNGK GGKHRVVTLA DSLIPLLKTQ
CERVVQITQQ DCTVPEYAGV WMPHQLVKKY PAERFRPNWQ YLFPAAKLSI DPESQQLRRH
YIDEKQLQRA VRNATYDAKI DKSVSPHTLR HSFATHLLLR GADIRTVQEQ LGHTDVKTTQ
IYTHVMQRGG NAVVSPLVSV VPPK
//
