ID A0A5B8B7Q4_9HYPH Unreviewed; 218 AA.
AC A0A5B8B7Q4;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 02-APR-2025, entry version 16.
DE RecName: Full=Acyl-homoserine-lactone synthase {ECO:0000256|ARBA:ARBA00012340, ECO:0000256|RuleBase:RU361135};
DE EC=2.3.1.184 {ECO:0000256|ARBA:ARBA00012340, ECO:0000256|RuleBase:RU361135};
DE AltName: Full=Autoinducer synthesis protein {ECO:0000256|RuleBase:RU361135};
GN ORFNames=FGU64_21630 {ECO:0000313|EMBL:QDC02794.1};
OS Mesorhizobium sp. 8.
OC Bacteria; Pseudomonadati; Pseudomonadota; Alphaproteobacteria;
OC Hyphomicrobiales; Phyllobacteriaceae; Mesorhizobium.
OX NCBI_TaxID=2584466 {ECO:0000313|EMBL:QDC02794.1, ECO:0000313|Proteomes:UP000312852};
RN [1] {ECO:0000313|EMBL:QDC02794.1, ECO:0000313|Proteomes:UP000312852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=8 {ECO:0000313|EMBL:QDC02794.1,
RC ECO:0000313|Proteomes:UP000312852};
RA Liu H., Jin D.;
RT "Mesorhizobium tritici sp. nov., isolated from isolated from rhizosphere
RT soil of wheat.";
RL Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a fatty acyl-[ACP] + S-adenosyl-L-methionine = an N-acyl-L-
CC homoserine lactone + S-methyl-5'-thioadenosine + holo-[ACP] + H(+);
CC Xref=Rhea:RHEA:10096, Rhea:RHEA-COMP:9685, Rhea:RHEA-COMP:14125,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:17509, ChEBI:CHEBI:55474,
CC ChEBI:CHEBI:59789, ChEBI:CHEBI:64479, ChEBI:CHEBI:138651;
CC EC=2.3.1.184; Evidence={ECO:0000256|ARBA:ARBA00048576,
CC ECO:0000256|RuleBase:RU361135};
CC -!- SIMILARITY: Belongs to the autoinducer synthase family.
CC {ECO:0000256|PROSITE-ProRule:PRU00533, ECO:0000256|RuleBase:RU361135}.
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DR EMBL; CP040914; QDC02794.1; -; Genomic_DNA.
DR RefSeq; WP_139954984.1; NZ_CP040914.1.
DR AlphaFoldDB; A0A5B8B7Q4; -.
DR KEGG; mesr:FGU64_21630; -.
DR OrthoDB; 6169313at2; -.
DR Proteomes; UP000312852; Chromosome.
DR GO; GO:0061579; F:N-acyl homoserine lactone synthase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0009372; P:quorum sensing; IEA:UniProtKB-UniRule.
DR GO; GO:0007165; P:signal transduction; IEA:TreeGrafter.
DR Gene3D; 3.40.630.30; -; 1.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR018311; Autoind_synth_CS.
DR InterPro; IPR001690; Autoind_synthase.
DR PANTHER; PTHR39322; ACYL-HOMOSERINE-LACTONE SYNTHASE; 1.
DR PANTHER; PTHR39322:SF1; ISOVALERYL-HOMOSERINE LACTONE SYNTHASE; 1.
DR Pfam; PF00765; Autoind_synth; 1.
DR PRINTS; PR01549; AUTOINDCRSYN.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR PROSITE; PS00949; AUTOINDUCER_SYNTH_1; 1.
DR PROSITE; PS51187; AUTOINDUCER_SYNTH_2; 1.
PE 3: Inferred from homology;
KW Autoinducer synthesis {ECO:0000256|ARBA:ARBA00022929, ECO:0000256|PROSITE-
KW ProRule:PRU00533};
KW Quorum sensing {ECO:0000256|ARBA:ARBA00022654, ECO:0000256|PROSITE-
KW ProRule:PRU00533}; Reference proteome {ECO:0000313|Proteomes:UP000312852};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|RuleBase:RU361135};
KW Transferase {ECO:0000256|RuleBase:RU361135}.
SQ SEQUENCE 218 AA; 23860 MW; 29ED50512D8B9C6A CRC64;
MILAIEGVDR HLHPDLFDQM FRMRAAVFAN RLGWDVTVVD GREIDWFDAE DPLYLFSIDE
VTEELKGAVR LLPTTGPNML RDVFSVLVPD GAVESPLIWE SSRFAINPGV GIGPAHQEAN
QVANATTVEL LCGLVEAAQL AGVEHIVSVF DARMARIFRS LDCGYEVIGV PTRIGAAMTY
AGLFETSDAL RRRLGSKAGL HKPVLSTVRA ASEITRRA
//
