ID A0A5B8JEU4_9ACTN Unreviewed; 238 AA.
AC A0A5B8JEU4;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 18-JUN-2025, entry version 18.
DE RecName: Full=urease {ECO:0000256|ARBA:ARBA00012934};
DE EC=3.5.1.5 {ECO:0000256|ARBA:ARBA00012934};
GN Name=ureA {ECO:0000313|EMBL:QDY80295.1};
GN ORFNames=FQU76_31525 {ECO:0000313|EMBL:QDY80295.1};
OS Streptomyces qinzhouensis.
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2599401 {ECO:0000313|EMBL:QDY80295.1, ECO:0000313|Proteomes:UP000320580};
RN [1] {ECO:0000313|EMBL:QDY80295.1, ECO:0000313|Proteomes:UP000320580}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SSL-25 {ECO:0000313|EMBL:QDY80295.1,
RC ECO:0000313|Proteomes:UP000320580};
RA Zhu P.;
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=urea + 2 H2O + H(+) = hydrogencarbonate + 2 NH4(+);
CC Xref=Rhea:RHEA:20557, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16199, ChEBI:CHEBI:17544, ChEBI:CHEBI:28938; EC=3.5.1.5;
CC Evidence={ECO:0000256|ARBA:ARBA00047778};
CC -!- PATHWAY: Nitrogen metabolism; urea degradation; CO(2) and NH(3) from
CC urea (urease route): step 1/1. {ECO:0000256|ARBA:ARBA00004897}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP042266; QDY80295.1; -; Genomic_DNA.
DR RefSeq; WP_146483692.1; NZ_CP042266.1.
DR AlphaFoldDB; A0A5B8JEU4; -.
DR KEGG; sqz:FQU76_31525; -.
DR OrthoDB; 9797217at2; -.
DR UniPathway; UPA00258; UER00370.
DR Proteomes; UP000320580; Chromosome.
DR GO; GO:0035550; C:urease complex; IEA:InterPro.
DR GO; GO:0016151; F:nickel cation binding; IEA:InterPro.
DR GO; GO:0009039; F:urease activity; IEA:UniProtKB-EC.
DR GO; GO:0043419; P:urea catabolic process; IEA:UniProtKB-UniPathway.
DR CDD; cd00390; Urease_gamma; 1.
DR Gene3D; 2.10.150.10; Urease, beta subunit; 1.
DR Gene3D; 3.30.280.10; Urease, gamma-like subunit; 1.
DR InterPro; IPR002019; Urease_beta-like.
DR InterPro; IPR036461; Urease_betasu_sf.
DR InterPro; IPR002026; Urease_gamma/gamma-beta_su.
DR InterPro; IPR036463; Urease_gamma_sf.
DR InterPro; IPR050069; Urease_subunit.
DR NCBIfam; NF009671; PRK13192.1; 1.
DR NCBIfam; TIGR00193; urease_gam; 1.
DR PANTHER; PTHR33569; UREASE; 1.
DR PANTHER; PTHR33569:SF1; UREASE; 1.
DR Pfam; PF00699; Urease_beta; 1.
DR Pfam; PF00547; Urease_gamma; 1.
DR SUPFAM; SSF51278; Urease, beta-subunit; 1.
DR SUPFAM; SSF54111; Urease, gamma-subunit; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:QDY80295.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000320580}.
SQ SEQUENCE 238 AA; 24601 MW; 02985AC2E65BDE4F CRC64;
MPLTPTERDR LLLFTAAELA RARLGRGLRL NVPEATALVA DTVCEAARDG LRLAEAIERG
RSVLGPGDLL PGVADVVTEI QVEAVFDDGT RLAAVAEPFG PVDRDDAAPG AVLPGPDDPW
VPEPVLTLAV RNTAAVPISV TSHFHFFEAN PRLDFDRAAA YGMRAAAPAG ASVRFDPGLT
VDIGLVPIGG DRIAIGFAGL VDGPLDAPGA RAAALRRAAA CGYLGAEPRD DTSEGSPA
//
