ID A0A5B8Z472_CYTDA Unreviewed; 631 AA.
AC A0A5B8Z472;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 28-JAN-2026, entry version 30.
DE RecName: Full=Selenocysteine-specific elongation factor {ECO:0000256|ARBA:ARBA00015953};
DE AltName: Full=SelB translation factor {ECO:0000256|ARBA:ARBA00031615};
GN Name=selB {ECO:0000313|EMBL:QED47667.1};
GN ORFNames=FSZ17_10580 {ECO:0000313|EMBL:QED47667.1};
OS Cytobacillus dafuensis (Bacillus dafuensis).
OC Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae;
OC Cytobacillus.
OX NCBI_TaxID=1742359 {ECO:0000313|EMBL:QED47667.1, ECO:0000313|Proteomes:UP000321555};
RN [1] {ECO:0000313|Proteomes:UP000321555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FJAT-25496 {ECO:0000313|Proteomes:UP000321555};
RA Zheng X.;
RL Submitted (AUG-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Translation factor necessary for the incorporation of
CC selenocysteine into proteins. It probably replaces EF-Tu for the
CC insertion of selenocysteine directed by the UGA codon. SelB binds GTP
CC and GDP. {ECO:0000256|ARBA:ARBA00025526}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; CP042593; QED47667.1; -; Genomic_DNA.
DR RefSeq; WP_082625189.1; NZ_CP042593.1.
DR AlphaFoldDB; A0A5B8Z472; -.
DR STRING; 1742359.GCA_001439625_00559; -.
DR KEGG; bda:FSZ17_10580; -.
DR OrthoDB; 9804504at2; -.
DR Proteomes; UP000321555; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR CDD; cd03696; SelB_II; 1.
DR CDD; cd15491; selB_III; 1.
DR Gene3D; 1.10.10.2770; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR015190; Elong_fac_SelB-wing-hlx_typ-2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR005225; Small_GTP-bd.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00475; selB; 1.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF09106; WHD_2nd_SelB; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:QED47667.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000321555}.
FT DOMAIN 3..174
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 631 AA; 72160 MW; 3A980BFACB23A5F9 CRC64;
MRKRFFTIGM AGHIDHGKTT LTKALTNIDT DRLKEEKERQ ISIELGFAPL YEDHEIQISV
VDVPGHERFI RQMIAGVAGI DLVVLVVAAD EGVMPQTREH LHILELLGIQ SGIVAVTKID
RVEDEFIDLV KEDILEELKG TVFEKAPFIL VDSIKNKGVD ELKARIVQYL KEQDTRDVRG
AFRLPIDQVF TVKGQGTVIR GTVYEGSVEE GQSLMVLPKR LETRARQLQV HHQPAKSAFA
GQRTAINLSG IAKEDLERGD VLVSSEHFIV TRTIDVVLKV AGDLEYMVKQ RMPIKCHIGT
SEVMGRIVFF DRNELKEENE EVLCQIRLEE EIVTKRGDRF ILRRPSPQET IGGGWVIDPR
GEKYKFGNQT VEDLEKKKEG TPKDRVIAAL VEAKSLSLSE LMTRTSIDEY ELQNCLSEKV
FLKYDADEYS LQSIKDLIIE EIYDRLRDYH NTNPMKQGLN KAELLQSMQN LYPKRLLDFV
LDQGIIEAIF NKKDQFVFLA DFSPHVPNNW KTRIENMLSA LKADELKVNF LNDYLKSAGI
PNDLVPDIKR FLVEQGEIVS LDEQYYYHGD LFRSAVERLK KGTGSEFEVG DAKEILGLSR
KYMIPFLERL DVLGLTKRVE NKRVWQNSRS N
//
