ID A0A5C2RXB9_9APHY Unreviewed; 553 AA.
AC A0A5C2RXB9;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 05-FEB-2025, entry version 16.
DE RecName: Full=Phosphomethylpyrimidine kinase {ECO:0008006|Google:ProtNLM};
GN ORFNames=L227DRAFT_554581 {ECO:0000313|EMBL:RPD55688.1};
OS Lentinus tigrinus ALCF2SS1-6.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Polyporaceae; Lentinus.
OX NCBI_TaxID=1328759 {ECO:0000313|EMBL:RPD55688.1, ECO:0000313|Proteomes:UP000313359};
RN [1] {ECO:0000313|EMBL:RPD55688.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ALCF2SS1-6 {ECO:0000313|EMBL:RPD55688.1};
RX PubMed=30398645;
RA Wu B., Xu Z., Knudson A., Carlson A., Chen N., Kovaka S., LaButti K.,
RA Lipzen A., Pennachio C., Riley R., Schakwitz W., Umezawa K., Ohm R.A.,
RA Grigoriev I.V., Nagy L.G., Gibbons J., Hibbett D.;
RT "Genomics and development of Lentinus tigrinus, a white-rot wood-decaying
RT mushroom with dimorphic fruiting bodies.";
RL Genome Biol. Evol. 0:0-0(2018).
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DR EMBL; ML122293; RPD55688.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5C2RXB9; -.
DR STRING; 1328759.A0A5C2RXB9; -.
DR OrthoDB; 10028886at2759; -.
DR Proteomes; UP000313359; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR GO; GO:0008902; F:hydroxymethylpyrimidine kinase activity; IEA:TreeGrafter.
DR GO; GO:0008972; F:phosphomethylpyrimidine kinase activity; IEA:InterPro.
DR GO; GO:0050334; F:thiaminase activity; IEA:InterPro.
DR GO; GO:0009228; P:thiamine biosynthetic process; IEA:InterPro.
DR CDD; cd01169; HMPP_kinase; 1.
DR CDD; cd19367; TenA_C_ScTHI20-like; 1.
DR Gene3D; 3.40.1190.20; -; 1.
DR Gene3D; 1.20.910.10; Heme oxygenase-like; 1.
DR InterPro; IPR016084; Haem_Oase-like_multi-hlx.
DR InterPro; IPR004399; HMP/HMP-P_kinase_dom.
DR InterPro; IPR013749; PM/HMP-P_kinase-1.
DR InterPro; IPR029056; Ribokinase-like.
DR InterPro; IPR004305; Thiaminase-2/PQQC.
DR InterPro; IPR027574; Thiaminase_II.
DR NCBIfam; TIGR00097; HMP-P_kinase; 1.
DR NCBIfam; TIGR04306; salvage_TenA; 1.
DR PANTHER; PTHR20858:SF17; HYDROXYMETHYLPYRIMIDINE_PHOSPHOMETHYLPYRIMIDINE KINASE THI20-RELATED; 1.
DR PANTHER; PTHR20858; PHOSPHOMETHYLPYRIMIDINE KINASE; 1.
DR Pfam; PF08543; Phos_pyr_kin; 2.
DR Pfam; PF03070; TENA_THI-4; 1.
DR SUPFAM; SSF48613; Heme oxygenase-like; 1.
DR SUPFAM; SSF53613; Ribokinase-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000313359}.
FT DOMAIN 16..195
FT /note="Pyridoxamine kinase/Phosphomethylpyrimidine kinase"
FT /evidence="ECO:0000259|Pfam:PF08543"
FT DOMAIN 233..310
FT /note="Pyridoxamine kinase/Phosphomethylpyrimidine kinase"
FT /evidence="ECO:0000259|Pfam:PF08543"
FT DOMAIN 339..551
FT /note="Thiaminase-2/PQQC"
FT /evidence="ECO:0000259|Pfam:PF03070"
SQ SEQUENCE 553 AA; 60167 MW; 953679ECED2EDD18 CRC64;
MGSNSPPAVL TIAGSDSGGG AGIQADLKSF TAFGCYGTSV ITALTAQNTK GVQGVHPTPS
DFLEQQLTSV LDDIEIRGIK TGMLYDAEHT RRIARKLKLH YGDASRVPPL VVDPVAVSTS
GHTLLHEDAV SVMIEELFPL ATLITPNKPE TELLLSRKGV SVKIESLEDM ISASEKVLAF
GSRAVLVKGG HVSLTLRDVH RISAARPEVS VVQETFLGEN MEILQVNEQD LASRQLVVDV
LREGETVTLF VSPRIDSSST HGTGCTLSAV IASLLAKGET VVEATRQATI YTHTGIETAF
PVGHGHGPLN HMHNLLPRAV PPPTATNPHP FTRILIQSSR TTWKAYVEHE FVKQLAMGTL
PRECFLHFVK QDYLYLKYYA RAYGLLVAKS STFGSIQTAT QTIINVINEV ATHKTFCAQW
GISEEELTAT PESPSTTAYG AYLLDIGLQG DSAKLIMALA ACLLGYGEVG LWLKKEASKP
DSWVKLDGNV YLKWIEDYSG EHYQGAVKLG IETIEALAAA DPPNALRFQE WCAIWEKCTR
LEKGFWDMAL NLL
//
