ID   A0A5C2SNY0_9APHY        Unreviewed;      1193 AA.
AC   A0A5C2SNY0;
DT   13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2019, sequence version 1.
DT   05-FEB-2025, entry version 17.
DE   RecName: Full=Histone deacetylase interacting domain-containing protein {ECO:0000259|SMART:SM00761};
GN   ORFNames=L227DRAFT_494514 {ECO:0000313|EMBL:RPD65008.1};
OS   Lentinus tigrinus ALCF2SS1-6.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Polyporales; Polyporaceae; Lentinus.
OX   NCBI_TaxID=1328759 {ECO:0000313|EMBL:RPD65008.1, ECO:0000313|Proteomes:UP000313359};
RN   [1] {ECO:0000313|EMBL:RPD65008.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ALCF2SS1-6 {ECO:0000313|EMBL:RPD65008.1};
RX   PubMed=30398645;
RA   Wu B., Xu Z., Knudson A., Carlson A., Chen N., Kovaka S., LaButti K.,
RA   Lipzen A., Pennachio C., Riley R., Schakwitz W., Umezawa K., Ohm R.A.,
RA   Grigoriev I.V., Nagy L.G., Gibbons J., Hibbett D.;
RT   "Genomics and development of Lentinus tigrinus, a white-rot wood-decaying
RT   mushroom with dimorphic fruiting bodies.";
RL   Genome Biol. Evol. 0:0-0(2018).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|PROSITE-ProRule:PRU00810}.
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DR   EMBL; ML122253; RPD65008.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A5C2SNY0; -.
DR   STRING; 1328759.A0A5C2SNY0; -.
DR   OrthoDB; 10265969at2759; -.
DR   Proteomes; UP000313359; Unassembled WGS sequence.
DR   GO; GO:0070822; C:Sin3-type complex; IEA:TreeGrafter.
DR   GO; GO:0003714; F:transcription corepressor activity; IEA:InterPro.
DR   GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IEA:TreeGrafter.
DR   FunFam; 1.20.1160.11:FF:000002; Paired amphipathic helix protein SIN3; 1.
DR   FunFam; 1.20.1160.11:FF:000003; Paired amphipathic helix SIN3-like protein; 1.
DR   Gene3D; 1.20.1160.11; Paired amphipathic helix; 2.
DR   InterPro; IPR013194; HDAC_interact_dom.
DR   InterPro; IPR003822; PAH.
DR   InterPro; IPR036600; PAH_sf.
DR   InterPro; IPR039774; Sin3-like.
DR   InterPro; IPR031693; Sin3_C.
DR   PANTHER; PTHR12346:SF0; SIN3A, ISOFORM G; 1.
DR   PANTHER; PTHR12346; SIN3B-RELATED; 1.
DR   Pfam; PF02671; PAH; 2.
DR   Pfam; PF08295; Sin3_corepress; 1.
DR   Pfam; PF16879; Sin3a_C; 1.
DR   SMART; SM00761; HDAC_interact; 1.
DR   SUPFAM; SSF47762; PAH2 domain; 2.
DR   PROSITE; PS51477; PAH; 1.
PE   4: Predicted;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW   ProRule:PRU00810}; Reference proteome {ECO:0000313|Proteomes:UP000313359};
KW   Repressor {ECO:0000256|ARBA:ARBA00022491}.
FT   DOMAIN          439..538
FT                   /note="Histone deacetylase interacting"
FT                   /evidence="ECO:0000259|SMART:SM00761"
FT   REGION          227..307
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          412..446
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          650..678
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          747..787
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          800..844
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1174..1193
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        664..673
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        766..781
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1193 AA;  133664 MW;  8DADB5A9F9668880 CRC64;
     MLFHGNPLLI QGFNTFLPPG YRIELNNEHS DTITVTTPLG RVTQRTTMYG IPQGLPRESM
     LAPGMVPPYT QPPFGLPPPP VLPVGIGNGS RPVTPMPIHA PPPPHIAHEM QVMRQPHPGS
     HSPAMQGGRD DAALLGSLNA RQTEKAQNGE FHHAINYLSK IKNRFSDDPE TYKQFLEILQ
     TYQKEQRHVQ DQSQVYAQVQ MLFKDAPDLM DEFKDFLPEA APPMHPAGLV GILPQPTTGP
     GMPGSFLPPE PPAAEKSTKT QNKRKKQKEP VAPPKAAGGR SAKRAKTANN QRTEPASPKF
     SPYQVPHSPQ LVNMHVHPVP APMHQQMQPV PIRPASVGPV GPVPPSAQDE LLFFDRAKKA
     LEGGGTYEEF LKLLNMFSRD IIDTKTLVDR AEVFLGDGEL LTQFKDLLGH EDQAGREEGP
     PGSLRTTAPD YYTALPPDDG QGPSYRRLPD SEVRLACSGR DRLCWSVLND EWVSHPTWAS
     EDAGFMTHKK NSFEDTLHKC EEERHEFQVQ IEALTRTIAN FNPIEARIET MSAEERSNFR
     LGADLGGMSP AVYERIVRKV YGFDGGNEVL RSLRETPATA VPVVLARLRR KDEEWRRAQR
     EWNRTWREID SKNFYKALDH QGITFKQNDK KIITAKHFFN EIEKVKKAAV ERDNGHPNGV
     KNGAGSSRGS TGSPPLHSWM RPIGHQLEYK FEDVELLQDC VKLVFTFLDH SSQHFSQAER
     RGMEKFLRSF IPTLFMLSAH DFNAACGPLT PGPDDDPSED QSALLDDEHP KAAPPPEKEV
     QQEGVSAQDL RTRLLKTAQE APQLGQDESP MLTSSTSPVA GESPQDISNP GVRHAEGDSG
     PYNVDVRTNA EDIWVRELKA SGAPSAGESR VVRRPFFAGT TFYTLLRLIQ ASLLYSRLLA
     CKEVGARMAA EKHASLFANP VAEHLGLDEP NGPPAVLKQA LEAFGSSREG DEQPNVLYMY
     LLDACEKVFE NELDQATFEE HMRWFFRTKA FNVFTLDRVI GAIVKQVQTV LGDNKCQELW
     YLLQQTRSAD KATAHDTIRY RREAERNVGS DEKLYRLDWD AAAKTLRIQL MGPEDPTVDE
     DETGEGRWRA YLASYVLSHP TEWTPNTNSS GYGPVFMKRN VHDGTEEGKD GVVEEERGMG
     ITVQRGTYKL MYEAGQEDVL VRRRGADEQR ALCERAARRE DERRRRGGRL LER
//