ID A0A5C3M8B9_9AGAR Unreviewed; 204 AA.
AC A0A5C3M8B9;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 18-JUN-2025, entry version 16.
DE RecName: Full=Iron-sulfur assembly protein 1 {ECO:0000256|ARBA:ARBA00071673};
GN ORFNames=BDQ12DRAFT_678618 {ECO:0000313|EMBL:TFK40933.1};
OS Crucibulum laeve.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Nidulariaceae; Crucibulum.
OX NCBI_TaxID=68775 {ECO:0000313|EMBL:TFK40933.1, ECO:0000313|Proteomes:UP000308652};
RN [1] {ECO:0000313|EMBL:TFK40933.1, ECO:0000313|Proteomes:UP000308652}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 166.37 {ECO:0000313|EMBL:TFK40933.1,
RC ECO:0000313|Proteomes:UP000308652};
RX PubMed=30886374; DOI=.1038/s41559-019-0834-1;
RA Varga T., Krizsan K., Foldi C., Dima B., Sanchez-Garcia M.,
RA Sanchez-Ramirez S., Szollosi G.J., Szarkandi J.G., Papp V., Albert L.,
RA Andreopoulos W., Angelini C., Antonin V., Barry K.W., Bougher N.L.,
RA Buchanan P., Buyck B., Bense V., Catcheside P., Chovatia M., Cooper J.,
RA Damon W., Desjardin D., Finy P., Geml J., Haridas S., Hughes K., Justo A.,
RA Karasinski D., Kautmanova I., Kiss B., Kocsube S., Kotiranta H.,
RA LaButti K.M., Lechner B.E., Liimatainen K., Lipzen A., Lukacs Z.,
RA Mihaltcheva S., Morgado L.N., Niskanen T., Noordeloos M.E., Ohm R.A.,
RA Ortiz-Santana B., Ovrebo C., Racz N., Riley R., Savchenko A., Shiryaev A.,
RA Soop K., Spirin V., Szebenyi C., Tomsovsky M., Tulloss R.E., Uehling J.,
RA Grigoriev I.V., Vagvolgyi C., Papp T., Martin F.M., Miettinen O.,
RA Hibbett D.S., Nagy L.G.;
RT "Megaphylogeny resolves global patterns of mushroom evolution.";
RL Nat. Ecol. Evol. 3:668-678(2019).
CC -!- FUNCTION: Involved in the assembly of mitochondrial and cytoplasmic
CC iron-sulfur proteins. Probably involved in the binding of an
CC intermediate of Fe/S cluster assembly. {ECO:0000256|ARBA:ARBA00054873}.
CC -!- SIMILARITY: Belongs to the HesB/IscA family.
CC {ECO:0000256|ARBA:ARBA00006718}.
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DR EMBL; ML213595; TFK40933.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5C3M8B9; -.
DR STRING; 68775.A0A5C3M8B9; -.
DR OrthoDB; 333486at2759; -.
DR Proteomes; UP000308652; Unassembled WGS sequence.
DR GO; GO:0005739; C:mitochondrion; IEA:TreeGrafter.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:TreeGrafter.
DR GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.
DR FunFam; 2.60.300.12:FF:000001; Iron-binding protein IscA; 1.
DR Gene3D; 2.60.300.12; HesB-like domain; 1.
DR InterPro; IPR050322; Fe-S_cluster_asmbl/transfer.
DR InterPro; IPR000361; FeS_biogenesis.
DR InterPro; IPR016092; FeS_cluster_insertion.
DR InterPro; IPR017870; FeS_cluster_insertion_CS.
DR InterPro; IPR035903; HesB-like_dom_sf.
DR NCBIfam; TIGR00049; iron-sulfur cluster assembly accessory protein; 1.
DR PANTHER; PTHR10072:SF41; IRON-SULFUR CLUSTER ASSEMBLY 1 HOMOLOG, MITOCHONDRIAL; 1.
DR PANTHER; PTHR10072; IRON-SULFUR CLUSTER ASSEMBLY PROTEIN; 1.
DR Pfam; PF01521; Fe-S_biosyn; 1.
DR SUPFAM; SSF89360; HesB-like domain; 1.
DR PROSITE; PS01152; HESB; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000308652}.
FT DOMAIN 99..197
FT /note="FeS cluster biogenesis"
FT /evidence="ECO:0000259|Pfam:PF01521"
FT REGION 70..91
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 204 AA; 21941 MW; 966C12BCF59D099D CRC64;
MPSSLPRIAR LNQNARLLPF LYPASSSSTV FTRRAMMSAL RTTPAYQPAP PLTESPPLVL
PSAASISRDA AAPQIAAKPP HAPKAERPRP KIKSAKAALT ITPTAVSRLH ALLNGPTPQL
IRIGVRNKGC AGLSYHLDYV DKPGKFDEVV EQDGVRVLID SKALFSIIGS EMDWKEDPLS
SKFVFANPNI KDACGCGESF NVVT
//
