ID A0A5C4ND81_9RHOB Unreviewed; 495 AA.
AC A0A5C4ND81;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 02-APR-2025, entry version 25.
DE RecName: Full=Phospholipase D {ECO:0000256|ARBA:ARBA00018392};
DE AltName: Full=Choline phosphatase {ECO:0000256|ARBA:ARBA00029594};
GN ORFNames=FHG71_15495 {ECO:0000313|EMBL:TNC67507.1};
OS Rubellimicrobium roseum.
OC Bacteria; Pseudomonadati; Pseudomonadota; Alphaproteobacteria;
OC Rhodobacterales; Roseobacteraceae; Rubellimicrobium.
OX NCBI_TaxID=687525 {ECO:0000313|EMBL:TNC67507.1, ECO:0000313|Proteomes:UP000305709};
RN [1] {ECO:0000313|EMBL:TNC67507.1, ECO:0000313|Proteomes:UP000305709}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIM 48858 {ECO:0000313|EMBL:TNC67507.1,
RC ECO:0000313|Proteomes:UP000305709};
RA Jiang L.;
RL Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Could be a virulence factor. {ECO:0000256|ARBA:ARBA00003145}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-
CC sn-glycero-3-phosphate + choline + H(+); Xref=Rhea:RHEA:14445,
CC ChEBI:CHEBI:15354, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57643, ChEBI:CHEBI:58608; EC=3.1.4.4;
CC Evidence={ECO:0000256|ARBA:ARBA00000798};
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TNC67507.1}.
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DR EMBL; VDFV01000028; TNC67507.1; -; Genomic_DNA.
DR RefSeq; WP_139082610.1; NZ_VDFV01000028.1.
DR AlphaFoldDB; A0A5C4ND81; -.
DR OrthoDB; 8828485at2; -.
DR Proteomes; UP000305709; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0004630; F:phospholipase D activity; IEA:TreeGrafter.
DR GO; GO:0009395; P:phospholipid catabolic process; IEA:TreeGrafter.
DR CDD; cd09140; PLDc_vPLD1_2_like_bac_1; 1.
DR CDD; cd09143; PLDc_vPLD1_2_like_bac_2; 1.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR InterPro; IPR025202; PLD-like_dom.
DR InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR InterPro; IPR015679; PLipase_D_fam.
DR PANTHER; PTHR18896:SF76; PHOSPHOLIPASE; 1.
DR PANTHER; PTHR18896; PHOSPHOLIPASE D; 1.
DR Pfam; PF00614; PLDc; 1.
DR Pfam; PF13091; PLDc_2; 1.
DR SMART; SM00155; PLDc; 2.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR PROSITE; PS50035; PLD; 2.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000305709};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 137..164
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
FT DOMAIN 352..379
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
SQ SEQUENCE 495 AA; 55010 MW; 69162427154CFD81 CRC64;
MDGDGVDARP ASDILRPGDT CWRIAHADRL RVIVDAADYF ATFRSVAQEA RHSLLLIGWD
FDTRIELDRA DGHSEVPNRL GRFLSWLVRN RPNLQIHMLE WDVGLLLALG RGSTPLRVAD
LVSSKRVRLQ LDHAHPAGAA HHQKIVVIDD VLAFCGGIDM TAGRWDTPAH QDHDPLRVSP
TLGWRFPPWH DVTTVVDGDA ARALGDLARE RWRRACGEEV APPPPTAPIW PEGLVPTLED
VEVGISRSAP DYDGRDGVRE IEALYLDIVK SARRHLYIES QYFASRRIAE AMAERLREPD
GPEIVVVNPL SAQGWLEEEA MGSARAKLLR MVRRADRYGR FGLYTPVAKG GTPIYVHAKV
VIMDDRLLRV GSSNLNNRSM GFDTECDLTV EVGPGDPDGA NRRRHIAALR ADLLAEHLGV
RPDDVEVALA QAGGFLIGAI EALRSDGRSL VPFKPPELNA LEEEVLAENE LLDPERASRR
WRPLSLPKRL PWSAA
//
