ID A0A5C6E8V8_9BACT Unreviewed; 527 AA.
AC A0A5C6E8V8;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 02-APR-2025, entry version 20.
DE SubName: Full=Aspartate/alanine antiporter {ECO:0000313|EMBL:TWU45014.1};
GN Name=aspT {ECO:0000313|EMBL:TWU45014.1};
GN ORFNames=Q31b_01850 {ECO:0000313|EMBL:TWU45014.1};
OS Novipirellula aureliae.
OC Bacteria; Pseudomonadati; Planctomycetota; Planctomycetia; Pirellulales;
OC Pirellulaceae; Novipirellula.
OX NCBI_TaxID=2527966 {ECO:0000313|EMBL:TWU45014.1, ECO:0000313|Proteomes:UP000315471};
RN [1] {ECO:0000313|EMBL:TWU45014.1, ECO:0000313|Proteomes:UP000315471}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Q31b {ECO:0000313|EMBL:TWU45014.1,
RC ECO:0000313|Proteomes:UP000315471};
RA Wiegand S., Jogler M., Boedeker C., Pinto D., Vollmers J., Rivas-Marin E.,
RA Kohn T., Peeters S.H., Heuer A., Rast P., Oberbeckmann S., Bunk B.,
RA Jeske O., Meyerdierks A., Storesund J.E., Kallscheuer N., Luecker S.,
RA Lage O.M., Pohl T., Merkel B.J., Hornburger P., Mueller R.-W., Bruemmer F.,
RA Labrenz M., Spormann A.M., Op Den Camp H., Overmann J., Amann R.,
RA Jetten M.S.M., Mascher T., Medema M.H., Devos D.P., Kaster A.-K.,
RA Ovreas L., Rohde M., Galperin M.Y., Jogler C.;
RT "Deep-cultivation of Planctomycetes and their phenomic and genomic
RT characterization uncovers novel biology.";
RL Submitted (FEB-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC -!- SIMILARITY: Belongs to the AAE transporter (TC 2.A.81) family.
CC {ECO:0000256|ARBA:ARBA00009854}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TWU45014.1}.
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DR EMBL; SJPY01000001; TWU45014.1; -; Genomic_DNA.
DR RefSeq; WP_146597810.1; NZ_SJPY01000001.1.
DR AlphaFoldDB; A0A5C6E8V8; -.
DR OrthoDB; 9155749at2; -.
DR Proteomes; UP000315471; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 1.
DR InterPro; IPR050144; AAE_transporter.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR InterPro; IPR006512; YidE_YbjL.
DR NCBIfam; TIGR01625; YidE_YbjL_dupl; 2.
DR PANTHER; PTHR30445; K(+)_H(+) ANTIPORTER SUBUNIT KHTT; 1.
DR PANTHER; PTHR30445:SF3; TRANSPORT PROTEIN YIDE-RELATED; 1.
DR Pfam; PF06826; Asp-Al_Ex; 2.
DR Pfam; PF02080; TrkA_C; 1.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 1.
DR PROSITE; PS51202; RCK_C; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000315471};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 53..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 80..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 353..372
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 444..464
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 502..524
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 260..343
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
SQ SEQUENCE 527 AA; 55310 MW; 684BA6D3DB997A82 CRC64;
MTPLLALLLI ITLGLALGKV SFRGISVGTS SILFVALLAG HLGIVIPEGL GTLGLALFVY
CIGIAAGPTF FRGLASNARI MATLGAVMVL TGIVVTWLCA KLFDLPADIA AGLMAGAMTS
TPALGAASES VVKPDNVAVA FGVAYPFGIA TIVLFVQLMM KRVAVSTIGS ETESPPEPRL
DDDRKIQRHV VEIANPGVAG KRPSEVAVSS DLSCQISRVF LDQRWRPTPS DYVFSLGDRV
MLVGQQEEGR RGAETLGVLC DIQDVVLDTD RERKEVVVTS QEIFGHTLKE LRLRSRFGVT
VTRIRRIDQE FVPSAHTRIE FGDTLSLVGE PGDLLRLQKV AGHRPRTLNE TDLLSLAFGL
TVGILVGQMA ILWGGVSVSL GTAGGPLCVG LVLGHFRRIG FVAGSFPPAA QILMTEGGLA
LFLADAGIHA GADVWSILQQ QGPVLCVAAT AIAVLPLAVG YLMASYCFGL TRLESLGATC
GGMTSTPGLA ALTSSTDSSE PVTSYIAAYP VALVLITIAA PLLIKLL
//
