ID A0A5C8KZI9_9FLAO Unreviewed; 590 AA.
AC A0A5C8KZI9;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 02-APR-2025, entry version 19.
DE SubName: Full=DEAD/DEAH box helicase {ECO:0000313|EMBL:TXK70591.1};
GN ORFNames=FT993_11770 {ECO:0000313|EMBL:TXK70591.1};
OS Mesonia sp. HuA40.
OC Bacteria; Pseudomonadati; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Mesonia.
OX NCBI_TaxID=2602761 {ECO:0000313|EMBL:TXK70591.1, ECO:0000313|Proteomes:UP000321259};
RN [1] {ECO:0000313|EMBL:TXK70591.1, ECO:0000313|Proteomes:UP000321259}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HuA40 {ECO:0000313|EMBL:TXK70591.1,
RC ECO:0000313|Proteomes:UP000321259};
RA He H., Huan R., Huang J., Liu D., Wang M., Liu C.;
RT "Complete genome of Mesonia sp. K4-1 reveals its adaptation to the Arctic
RT Ocean.";
RL Submitted (AUG-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DEAD box helicase family.
CC {ECO:0000256|ARBA:ARBA00038437, ECO:0000256|RuleBase:RU000492}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TXK70591.1}.
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DR EMBL; VRLT01000062; TXK70591.1; -; Genomic_DNA.
DR RefSeq; WP_147862757.1; NZ_VRLT01000062.1.
DR AlphaFoldDB; A0A5C8KZI9; -.
DR OrthoDB; 9785240at2; -.
DR Proteomes; UP000321259; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR CDD; cd00268; DEADc; 1.
DR CDD; cd12252; RRM_DbpA; 1.
DR CDD; cd18787; SF2_C_DEAD; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR005580; DbpA/CsdA_RNA-bd_dom.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR050079; DEAD_box_RNA_helicase.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C-like.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000629; RNA-helicase_DEAD-box_CS.
DR InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR PANTHER; PTHR47959:SF13; ATP-DEPENDENT RNA HELICASE RHLE; 1.
DR PANTHER; PTHR47959; ATP-DEPENDENT RNA HELICASE RHLE-RELATED; 1.
DR Pfam; PF03880; DbpA; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00039; DEAD_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51195; Q_MOTIF; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU000492};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|RuleBase:RU000492};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000492};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU000492};
KW Reference proteome {ECO:0000313|Proteomes:UP000321259}.
FT DOMAIN 2..30
FT /note="DEAD-box RNA helicase Q"
FT /evidence="ECO:0000259|PROSITE:PS51195"
FT DOMAIN 34..205
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 232..376
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 531..590
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 2..30
FT /note="Q motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00552"
FT COMPBIAS 537..549
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 550..561
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 590 AA; 66705 MW; 925DE13E1DAE5D9D CRC64;
MNKFEELGLD AQIVNAVNDM GFESPSEVQE KAIPILLEQD TDLVALAQTG TGKTAAFGFP
LIQRINANSK KTQGLILSPT RELCLQITNE LKNYSKYVKG LSTVAIYGGA SISEQANQIK
RGAQIIVATP GRMKDMVGRR MIDISTIDYC ILDEADEMLN MGFYEDITDI LSHTPKEKKT
WLFSATMPKE VATIASKFMH KPVEITVGTK NEGSKNVNHE YFLVGPRDRY AALKRLADAH
PDIFSVIFCR TKRDTQKVAE KLIEDGYNAA ALHGDLSQNQ RDLVMRSFRS RQIQMLVATD
VAARGIDVDD ITHVINYQLP DEVETYTHRS GRTGRAGKKG TSMVIITKSE MRKIKSIERI
IKQSFERKEV PSGEEICQVQ LLHLAKDIKN TTINHEIEEY LPQIEALLAD FSKEEIIKKV
FSVEFTRFHN YYKNANTINS PKPGDHAAED NGFSTRFFIN VGEKDGFDWM SLKDFLKEQL
DLGRDAVSRV DVKNNFSFFN TDTAEVENVL STFKEFSYQG RAINAEVTKA NEGRPDKFKR
KRGERKGGRK KFDDRGGDQK RSSRRSKPRN AGGKRSANIK SSVNRRRNKK
//
