ID A0A5C8NV72_9BACI Unreviewed; 523 AA.
AC A0A5C8NV72;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 18-JUN-2025, entry version 26.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=FHP05_07850 {ECO:0000313|EMBL:TXL65042.1};
OS Cerasibacillus terrae.
OC Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae;
OC Cerasibacillus.
OX NCBI_TaxID=2498845 {ECO:0000313|EMBL:TXL65042.1, ECO:0000313|Proteomes:UP000321574};
RN [1] {ECO:0000313|EMBL:TXL65042.1, ECO:0000313|Proteomes:UP000321574}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CC-CFT480 {ECO:0000313|EMBL:TXL65042.1,
RC ECO:0000313|Proteomes:UP000321574};
RA Lin S.-Y., Tsai C.-F., Young C.-C.;
RT "Cerasibacillus sp. nov., isolated from maize field.";
RL Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TXL65042.1}.
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DR EMBL; VDUW01000004; TXL65042.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5C8NV72; -.
DR OrthoDB; 9792686at2; -.
DR Proteomes; UP000321574; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR033463; sCache_3.
DR InterPro; IPR029151; Sensor-like_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR016120; Sig_transdc_His_kin_SpoOB.
DR InterPro; IPR039506; SPOB_a.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43547:SF3; SENSOR PROTEIN CITS; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF17203; sCache_3_2; 1.
DR Pfam; PF14689; SPOB_a; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR SUPFAM; SSF55890; Sporulation response regulatory protein Spo0B; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:TXL65042.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000321574};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 166..192
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 217..250
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 332..523
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 523 AA; 58361 MW; E60B2FF107478F5F CRC64;
MKKISLRTKI LVLIIGLILF VTILLTVFYS LIESSNTEDE IGDKALQFAT MISFMPTIKE
AFATESPEEI IQPIAEEIRM MTGAEFVVIG NTKSIRYSHP TPTKVGKKMI GGDNDKALLK
GQYYISKATG SLGPSLRGKA PIFNEKGEII GIVSVGFMID DVKTIIFSRL LTIGKVSFFV
LLIGVMGGIL LARDIRKDIL GLEPYEIVSL YRDRDAILAS VHEGIIAIDE KGMITMMNQS
AKSILGITED FYSKGFDEVF PELEVTLKHD NYGRVNNQEF IVNQRHVIIN VTPIIENDSI
EGAVISFRDK TEIKEMIHTL AEVRKYSEDL RAQTHEYTNK LYVLSGLLQL EKYDEAIDLL
QIEASYTSSQ NKILFEQIKD PTVQALLLGK LAKSSELKIE LIINPNSYLN RIPNTIKRTK
VITIIGNLLD NALEAVIHFS KKEVTFFAID IGDDIIFEIA DSGPGITNSE ISQIFNRGYS
TKRDKNRGHG LALVKETLSE LNGQIEINHG SEGGMIFSVF IPK
//
