ID A0A5D0ND53_9ACTN Unreviewed; 585 AA.
AC A0A5D0ND53;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 28-JAN-2026, entry version 26.
DE SubName: Full=Selenocysteine-specific translation elongation factor {ECO:0000313|EMBL:TYB42464.1};
GN Name=selB {ECO:0000313|EMBL:TYB42464.1};
GN ORFNames=FXF69_32185 {ECO:0000313|EMBL:TYB42464.1};
OS Actinomadura chibensis.
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Thermomonosporaceae; Actinomadura.
OX NCBI_TaxID=392828 {ECO:0000313|EMBL:TYB42464.1, ECO:0000313|Proteomes:UP000323380};
RN [1] {ECO:0000313|EMBL:TYB42464.1, ECO:0000313|Proteomes:UP000323380}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 14158 {ECO:0000313|EMBL:TYB42464.1,
RC ECO:0000313|Proteomes:UP000323380};
RA Songsumanus A., Kuncharoen N., Kudo T., Yuki M., Igarashi Y.,
RA Tanasupawat S.;
RT "Actinomadura sp. nov. CYP1-5 isolated from mountain soil.";
RL Submitted (AUG-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TYB42464.1}.
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DR EMBL; VSFG01000008; TYB42464.1; -; Genomic_DNA.
DR RefSeq; WP_067887585.1; NZ_VSFG01000008.1.
DR AlphaFoldDB; A0A5D0ND53; -.
DR STRING; 1220554.GCA_001552135_01748; -.
DR Proteomes; UP000323380; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR Gene3D; 1.10.10.2770; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR00475; selB; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:TYB42464.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00023134};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000323380}.
FT DOMAIN 1..170
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 585 AA; 61471 MW; 3EB07454632A069D CRC64;
MHVIATAGHV DHGKSTLVRA LTGMEPDRLE EERRRRLTID LGFAWTRLPG AGEVAFVDVP
GHERFVANML AGVGPAPAVL FVVAADEGWM PQSAEHLEAL DALGVSHGVL AVTRSDLADP
APAIAEAREW MADGTLRDLP AVAVSATTGA GLDDLRAALA DLVAGLPRPD PEAPVRLWAD
RSFSVRGAGT VVTATLGAGT VRVGDELLNT EGRAVRVRGI EALGERRDRV AATARVALNL
RGVDRAAVPR GLPLLTPGAW RTAAEVDVEL RPTSSAALPE RLVLHIGTAA VPCRLRPLGP
AHGRLRLDRP LPLRYGDRAV LRDPGRRRIA AGLRVLDVDP PPLARRGAAR ARAAELSGVR
TAADVAAARL ARGLLRGADL AAMGLPAPGA PRHGDWWTSD ERWARYAADL AEAERRHRAD
HPLEPGMPVA AAVQRLGLPD PALVPALAAD AGLDCASGLL APPGHVAALP GALDEAVRSL
ERELAAAPFA APTAGRLAEL GLGNAELAAA ERLGRLVRVA PGIVLLPDVD RRALDVLKAL
PQPFTLSEAR RAMGTTRRVA VPLLELLAAR GLTRRTTDDG HEVTG
//
