ID A0A5D2UKA9_GOSMU Unreviewed; 115 AA.
AC A0A5D2UKA9;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 05-FEB-2025, entry version 12.
DE RecName: Full=Mediator of RNA polymerase II transcription subunit 11 {ECO:0000256|RuleBase:RU364147};
DE AltName: Full=Mediator complex subunit 11 {ECO:0000256|RuleBase:RU364147};
GN Name=MED11 {ECO:0000256|RuleBase:RU364147};
GN ORFNames=E1A91_D06G188400v1 {ECO:0000313|EMBL:TYI78107.1};
OS Gossypium mustelinum (Cotton) (Gossypium caicoense).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=34275 {ECO:0000313|EMBL:TYI78107.1, ECO:0000313|Proteomes:UP000323597};
RN [1] {ECO:0000313|EMBL:TYI78107.1, ECO:0000313|Proteomes:UP000323597}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1408120.09 {ECO:0000313|EMBL:TYI78107.1};
RA Chen Z.J., Sreedasyam A., Ando A., Song Q., De L., Hulse-Kemp A., Ding M.,
RA Ye W., Kirkbride R., Jenkins J., Plott C., Lovell J., Lin Y.-M., Vaughn R.,
RA Liu B., Li W., Simpson S., Scheffler B., Saski C., Grover C., Hu G.,
RA Conover J., Carlson J., Shu S., Boston L., Williams M., Peterson D.,
RA Mcgee K., Jones D., Wendel J., Stelly D., Grimwood J., Schmutz J.;
RT "WGS assembly of Gossypium mustelinum.";
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the Mediator complex, a coactivator involved in
CC the regulated transcription of nearly all RNA polymerase II-dependent
CC genes. Mediator functions as a bridge to convey information from gene-
CC specific regulatory proteins to the basal RNA polymerase II
CC transcription machinery. Mediator is recruited to promoters by direct
CC interactions with regulatory proteins and serves as a scaffold for the
CC assembly of a functional pre-initiation complex with RNA polymerase II
CC and the general transcription factors. {ECO:0000256|RuleBase:RU364147}.
CC -!- SUBUNIT: Component of the Mediator complex.
CC {ECO:0000256|RuleBase:RU364147}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU364147}.
CC -!- SIMILARITY: Belongs to the Mediator complex subunit 11 family.
CC {ECO:0000256|ARBA:ARBA00008186, ECO:0000256|RuleBase:RU364147}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM017654; TYI78107.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5D2UKA9; -.
DR SMR; A0A5D2UKA9; -.
DR Proteomes; UP000323597; Chromosome d06.
DR GO; GO:0016592; C:mediator complex; IEA:InterPro.
DR GO; GO:0003712; F:transcription coregulator activity; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR FunFam; 1.10.287.3490:FF:000002; Mediator of RNA polymerase II transcription subunit 11; 1.
DR Gene3D; 1.10.287.3490; -; 1.
DR InterPro; IPR019404; Mediator_Med11.
DR PANTHER; PTHR22890; MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 11; 1.
DR Pfam; PF10280; Med11; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|RuleBase:RU364147};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU364147};
KW Reference proteome {ECO:0000313|Proteomes:UP000323597};
KW Transcription {ECO:0000256|RuleBase:RU364147};
KW Transcription regulation {ECO:0000256|RuleBase:RU364147}.
SQ SEQUENCE 115 AA; 13469 MW; 5940BD60B1B6752A CRC64;
MDSPTQNTSL RRLQNVEKRI VRVLELAGGV MDELANPTGP RKEFINNHCR EFMKMIKDIQ
VTLRDEIKSA CEYRPFEKCD YSSRISNEIC CKKLEYVLFQ LDAMKQTIDE YQATV
//
