ID A0A5E3X125_9AGAM Unreviewed; 665 AA.
AC A0A5E3X125;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 02-APR-2025, entry version 20.
DE RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012251};
DE EC=2.3.2.31 {ECO:0000256|ARBA:ARBA00012251};
GN ORFNames=PNH_LOCUS8894 {ECO:0000313|EMBL:VDB99498.1};
OS Peniophora sp. CBMAI 1063.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Russulales; Peniophoraceae; Peniophora.
OX NCBI_TaxID=718367 {ECO:0000313|EMBL:VDB99498.1, ECO:0000313|Proteomes:UP000365756};
RN [1] {ECO:0000313|EMBL:VDB99498.1, ECO:0000313|Proteomes:UP000365756}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Persinoti F G.;
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.;
CC EC=2.3.2.31; Evidence={ECO:0000256|ARBA:ARBA00001798};
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DR EMBL; UWZB01000218; VDB99498.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5E3X125; -.
DR OrthoDB; 10009520at2759; -.
DR Proteomes; UP000365756; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd20335; BRcat_RBR; 1.
DR CDD; cd00590; RRM_SF; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR031127; E3_UB_ligase_RBR.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR044066; TRIAD_supradom.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR Pfam; PF01485; IBR; 1.
DR Pfam; PF00076; RRM_1; 1.
DR SUPFAM; SSF57850; RING/U-box; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS51873; TRIAD; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000365756};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 494..665
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
SQ SEQUENCE 665 AA; 74295 MW; 813C8CAF95B4381D CRC64;
MSCPVHKYIK ITLGPGFVIQ DVTTHNETRN LVIDNLPSGT KKDALVRLLE SFGGTVVAVQ
MSSGGAYEGG KPFFARVQMK SHREAIAVAN GLNGMKALRC NGELFVRPEL PRAAIRSQVS
DSSIRVSWTL PTTSLYLGFD TLEGAQMAVR TADGYDWNGY WVTASIYSGI PVVKEYDVRL
SGLPPNVDHE LVCKRFGVHR TDIMRDKPSR FLRGFGIPQA KNRLEGFGRI VGFDVSPAPY
KDGVVRAWCH FETPDIALAA RELDGIEQRC LNDEKIAISR VYSLEYPIRR TVHRHIGDAI
SNLREVVHRF LPGCLLRIPD HNKRQDTITF EINAEDSKSL LDIRARLADI VQGELVMDGN
GPLWDRILST PFGADRMNSI RSSNREVLIV VRKLQSFIRV IGPPEKRASA IAAIRQLVAT
FQRQPVHTVT LPASRPGLFM HPSLIRLREK HGTDKLWLDI RNRRLCIRGD EAMYAEVQTA
VYTANKEVHS HDHSRTLCPV CFDEPTPSVV LSCGDVYCKE CLAGYLAAGA ETRHFPLRCF
GDDGKCQKPI PLHVAQDVLQ DEQWDLLVAA AFNTHVVAKP DEFRFCPTPD CQQVYRPGAK
DTVYSCPECL LSICPYCEVE YHEGSTCDDQ SYRINGAFDE ASVGLQPYDL LALSDAYVLG
VYGDF
//
