ID   A0A5E4CPG0_MARMO        Unreviewed;       886 AA.
AC   A0A5E4CPG0;
DT   13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2019, sequence version 1.
DT   08-OCT-2025, entry version 18.
DE   RecName: Full=Neutral sphingomyelinase activation associated factor {ECO:0008006|Google:ProtNLM};
GN   ORFNames=MONAX_5E020077 {ECO:0000313|EMBL:VTJ83778.1};
OS   Marmota monax (Woodchuck).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC   Xerinae; Marmotini; Marmota.
OX   NCBI_TaxID=9995 {ECO:0000313|EMBL:VTJ83778.1, ECO:0000313|Proteomes:UP000335636};
RN   [1] {ECO:0000313|EMBL:VTJ83778.1, ECO:0000313|Proteomes:UP000335636}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Alioto T., Alioto T.;
RL   Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CABDUW010001759; VTJ83778.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A5E4CPG0; -.
DR   Proteomes; UP000335636; Unassembled WGS sequence.
DR   CDD; cd06071; Beach; 1.
DR   CDD; cd01201; PH_BEACH; 1.
DR   FunFam; 1.10.1540.10:FF:000001; neurobeachin isoform X1; 1.
DR   FunFam; 2.30.29.30:FF:000367; Neutral sphingomyelinase activation associated factor; 1.
DR   FunFam; 2.130.10.10:FF:000336; Neutral sphingomyelinase activation-associated factor; 1.
DR   Gene3D; 1.10.1540.10; BEACH domain; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR   InterPro; IPR000409; BEACH_dom.
DR   InterPro; IPR036372; BEACH_dom_sf.
DR   InterPro; IPR050865; BEACH_Domain.
DR   InterPro; IPR057496; FAN-like_PH.
DR   InterPro; IPR004182; GRAM.
DR   InterPro; IPR023362; PH-BEACH_dom.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR13743; BEIGE/BEACH-RELATED; 1.
DR   PANTHER; PTHR13743:SF123; PROTEIN FAN; 1.
DR   Pfam; PF02138; Beach; 1.
DR   Pfam; PF02893; GRAM; 1.
DR   Pfam; PF25400; PH_FAN; 1.
DR   Pfam; PF00400; WD40; 4.
DR   SMART; SM01026; Beach; 1.
DR   SMART; SM00568; GRAM; 1.
DR   SMART; SM00320; WD40; 5.
DR   SUPFAM; SSF81837; BEACH domain; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS50197; BEACH; 1.
DR   PROSITE; PS51783; PH_BEACH; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 3.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000335636};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW   ProRule:PRU00221}.
FT   DOMAIN          189..286
FT                   /note="BEACH-type PH"
FT                   /evidence="ECO:0000259|PROSITE:PS51783"
FT   DOMAIN          290..575
FT                   /note="BEACH"
FT                   /evidence="ECO:0000259|PROSITE:PS50197"
FT   REPEAT          713..743
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          762..803
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          804..845
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
SQ   SEQUENCE   886 AA;  100449 MW;  3B9ABD303EEC9CB4 CRC64;
     MAFIRKKQQE QQLQLYSKER FSLLLLNLEE YYFEQHTANH VQCNGSQEER KIRGSLKICS
     KSVIFEPDAI SQPIIKIPLR DCIKIGKHGE NGANQHFAKA KSGGISLIFS QVYFIKEHNI
     VAPYKIERGK MEYVFELDVS GKVEDVVETL LQLHRASCLD KLGDQTAMIT AILQSRLART
     SFDKNRFQSV SEKLHMECKA EMVTPLVTNP GHVCITDTNL YFQPLNGYPK PVVQITLQDV
     RRIYKRRHGL MPLGLEVFCT EDNLCSDIYL KFYESQDRDD LYFYIATYLE HHVAEHTAES
     YMLQWQRGHL SNYQYLLHLN NLADRSCNDL SQYPVFPWVI SDYYSSELDL SNPATFRDLS
     KPVGALNKER LERLLIRYEE MPEPKFMYGS HYSSPGYVLF YLVRIAPEYM LCLQNGRFDN
     ADRMFNSIAE TWKNCLDGAT DFKELIPEFY GDDVSFLVNS LKLDLGKRQG GQMVDDVELP
     LWASSPEDFL QKSKEALESN YVSEHLHEWI DLIFGYKQKG SDAVGAHNVF HPLTYEGGVD
     LNSIEDPDEK VAMLTQILEF GQTPKQLFVT PHPRRITPKF KSLSQTSSYN APIVDSPVSP
     GEESFEDLTE ESKTLAWNNI TKLQLHEQYK IHKEAVTGIA VSCNGSSVFT TSQDSTLKMF
     SKESKMLQRS ISFSNMALSS CLLLPGDATV ISSSWDNNVY FYSIAFGRRQ DTLMGHDDAV
     SKICWHNDRL YSASWDSTVK VWSGVPAEMP GTKKHQFDLL AELEHEVSVD TISLNAASTL
     LVSGTKEGTV NIWDLATATL LHQIPCHSGT VCDAAFSPDS RHVLSTGADG CLNVIDVQTG
     MLISSLTSDE PQRYSSQAGD EDICKHTIIS FGCLVNVTYP SFMMTE
//