ID A0A5E4NI23_9HEMI Unreviewed; 500 AA.
AC A0A5E4NI23;
DT 13-NOV-2019, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2019, sequence version 1.
DT 18-JUN-2025, entry version 21.
DE RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012251};
DE EC=2.3.2.31 {ECO:0000256|ARBA:ARBA00012251};
GN ORFNames=CINCED_3A024034 {ECO:0000313|EMBL:VVC43319.1};
OS Cinara cedri.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Hemiptera; Sternorrhyncha; Aphidomorpha;
OC Aphidoidea; Aphididae; Lachninae; Cinara.
OX NCBI_TaxID=506608 {ECO:0000313|EMBL:VVC43319.1, ECO:0000313|Proteomes:UP000325440};
RN [1] {ECO:0000313|EMBL:VVC43319.1, ECO:0000313|Proteomes:UP000325440}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Alioto T., Alioto T., Gomez Garrido J.;
RL Submitted (AUG-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.;
CC EC=2.3.2.31; Evidence={ECO:0000256|ARBA:ARBA00001798};
CC -!- SIMILARITY: Belongs to the RBR family. Ariadne subfamily.
CC {ECO:0000256|ARBA:ARBA00005884}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CABPRJ010002368; VVC43319.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5E4NI23; -.
DR OrthoDB; 10009520at2759; -.
DR Proteomes; UP000325440; Unassembled WGS sequence.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd20343; BRcat_RBR_HHARI-like; 1.
DR CDD; cd20356; Rcat_RBR_HHARI-like; 1.
DR CDD; cd16626; RING-HC_RBR_HHARI; 1.
DR FunFam; 1.20.120.1750:FF:000002; RBR-type E3 ubiquitin transferase; 1.
DR FunFam; 3.30.40.10:FF:000019; RBR-type E3 ubiquitin transferase; 1.
DR Gene3D; 1.20.120.1750; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR045840; Ariadne.
DR InterPro; IPR048962; ARIH1-like_UBL.
DR InterPro; IPR031127; E3_UB_ligase_RBR.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR044066; TRIAD_supradom.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR Pfam; PF19422; Ariadne; 1.
DR Pfam; PF01485; IBR; 1.
DR Pfam; PF22191; IBR_1; 1.
DR Pfam; PF21235; UBA_ARI1; 1.
DR SMART; SM00647; IBR; 2.
DR SUPFAM; SSF57850; RING/U-box; 3.
DR PROSITE; PS51873; TRIAD; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000325440};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 127..338
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT DOMAIN 131..176
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
SQ SEQUENCE 500 AA; 59014 MW; E553318046390149 CRC64;
MDLYEDGTID VDSGNETSGD DVNFTMEFDV QHEREKNQDV DDFSFEVLST ENIVQYMIDC
IKEVNTVLQM PATTTRILLN YFKWDKEKLM EQFYDGDQDK LFSEARVINP FKRTQPIIQR
PLPRRRRTKD CAICFARFPN NMMTGLECNH CFCTQCWTEY LTTKIIEEGA GQTIACAASG
CDILVDDATV MRLVRDPKVR MKYQHLITNS FVECNRLLRW CPSPDCNNVV KVQYIDSKPV
VCRCLHVFCF VCGENWHDPV KCNLLRKWIK KCDNDSETSN WIAANTKECP KCNVTIEKDG
GCNHLICKNQ ICKYDFCWVC MGPWEPHGSS WYNCSRYDEE EAKAARDAQE KSRAALQRYL
FYCNRYMNHM QSLKFEHKLY SSVKEKMQQH NMSSNEVQFL KKAVDTLCQC RQTLMYTYVF
AYYLKKNNQS ILFEDNQRDL ESATETLSEY LERDITSKNI ANIKQNVQDK YRYCENRRKV
LLEHVHEGYE EDWWNYTESL
//
