ID A0A5F5PN31_HORSE Unreviewed; 231 AA.
AC A0A5F5PN31;
DT 11-DEC-2019, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 1.
DT 18-JUN-2025, entry version 22.
DE SubName: Full=Bone marrow stromal cell antigen 2 {ECO:0000313|Ensembl:ENSECAP00000049757.1};
GN Name=BST2 {ECO:0000313|Ensembl:ENSECAP00000049757.1,
GN ECO:0000313|VGNC:VGNC:96656};
OS Equus caballus (Horse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX NCBI_TaxID=9796 {ECO:0000313|Ensembl:ENSECAP00000049757.1, ECO:0000313|Proteomes:UP000002281};
RN [1] {ECO:0000313|Ensembl:ENSECAP00000049757.1, ECO:0000313|Proteomes:UP000002281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000049757.1,
RC ECO:0000313|Proteomes:UP000002281};
RX PubMed=19892987; DOI=10.1126/science.1178158;
RG Broad Institute Genome Sequencing Platform;
RG Broad Institute Whole Genome Assembly Team;
RA Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F.,
RA Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O.,
RA Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.,
RA Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T.,
RA Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S.,
RA Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G.,
RA Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R.,
RA Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A.,
RA Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J.,
RA Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.;
RT "Genome sequence, comparative analysis, and population genetics of the
RT domestic horse.";
RL Science 326:865-867(2009).
RN [2] {ECO:0000313|Ensembl:ENSECAP00000049757.1}
RP IDENTIFICATION.
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000049757.1};
RG Ensembl;
RL Submitted (MAR-2025) to UniProtKB.
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DR AlphaFoldDB; A0A5F5PN31; -.
DR Ensembl; ENSECAT00000078868.2; ENSECAP00000049757.1; ENSECAG00000003563.4.
DR VGNC; VGNC:96656; BST2.
DR GeneTree; ENSGT00390000013782; -.
DR Proteomes; UP000002281; Chromosome 21.
DR Bgee; ENSECAG00000003563; Expressed in chorionic villus and 20 other cell types or tissues.
DR ExpressionAtlas; A0A5F5PN31; baseline.
DR GO; GO:0009986; C:cell surface; IBA:GO_Central.
DR GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008191; F:metalloendopeptidase inhibitor activity; IBA:GO_Central.
DR GO; GO:0051607; P:defense response to virus; IBA:GO_Central.
DR GO; GO:0045087; P:innate immune response; IBA:GO_Central.
DR Gene3D; 1.20.5.1700; -; 1.
DR InterPro; IPR024886; BST2.
DR PANTHER; PTHR15190; BONE MARROW STROMAL ANTIGEN 2; 1.
DR PANTHER; PTHR15190:SF1; BONE MARROW STROMAL ANTIGEN 2; 1.
DR Pfam; PF16716; BST2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002281};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 49..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 231 AA; 25493 MW; 6C2BA7C0DED66456 CRC64;
MLTRGGPQKL PASAPNSCPD SHIQGQIWLA LTSYHNWPVP MGDHRLLRWL LLVVVVVVVV
LFLLVTTIIF AVQANSKACK DGLRAEQECR NGTHFLEHQL RRAQEVLRGT ETQAAICNQT
VVTLRASLEM AKADRREQLA RVQELEDKGM MGPQVGTTTL PARRTPSAPW WPLCSCPWAS
GICRPEVPGS RRHNLDWSGS PAFQTSLTWR FQEHCRLLGG GAGGWSSSGG P
//
