ID A0A5J5A7Q6_9ASTE Unreviewed; 641 AA.
AC A0A5J5A7Q6;
DT 11-DEC-2019, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 1.
DT 18-JUN-2025, entry version 24.
DE RecName: Full=Phospholipase D alpha 1 {ECO:0000256|ARBA:ARBA00041119};
DE EC=3.1.4.4 {ECO:0000256|ARBA:ARBA00012027};
DE AltName: Full=Choline phosphatase 1 {ECO:0000256|ARBA:ARBA00042228};
DE AltName: Full=Phosphatidylcholine-hydrolyzing phospholipase D 1 {ECO:0000256|ARBA:ARBA00042781};
GN ORFNames=F0562_007316 {ECO:0000313|EMBL:KAA8525461.1};
OS Nyssa sinensis.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; Cornales; Nyssaceae; Nyssa.
OX NCBI_TaxID=561372 {ECO:0000313|EMBL:KAA8525461.1, ECO:0000313|Proteomes:UP000325577};
RN [1] {ECO:0000313|EMBL:KAA8525461.1, ECO:0000313|Proteomes:UP000325577}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=J267 {ECO:0000313|EMBL:KAA8525461.1};
RC TISSUE=Leaf {ECO:0000313|EMBL:KAA8525461.1};
RA Yang X., Kang M., Yang Y., Xiong H., Wang M., Zhang Z., Wang Z., Wu H.,
RA Ma T., Liu J., Xi Z.;
RT "A chromosome-level genome assembly of the Chinese tupelo Nyssa sinensis.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-
CC sn-glycero-3-phosphate + choline + H(+); Xref=Rhea:RHEA:14445,
CC ChEBI:CHEBI:15354, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57643, ChEBI:CHEBI:58608; EC=3.1.4.4;
CC Evidence={ECO:0000256|ARBA:ARBA00000798};
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|ARBA:ARBA00001913};
CC -!- SIMILARITY: Belongs to the phospholipase D family. C2-PLD subfamily.
CC {ECO:0000256|ARBA:ARBA00010683}.
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DR EMBL; CM018046; KAA8525461.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5J5A7Q6; -.
DR OrthoDB; 14911at2759; -.
DR Proteomes; UP000325577; Miscellaneous, Linkage group lg3.
DR GO; GO:0005886; C:plasma membrane; IEA:TreeGrafter.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004630; F:phospholipase D activity; IEA:UniProtKB-EC.
DR GO; GO:0009395; P:phospholipid catabolic process; IEA:TreeGrafter.
DR CDD; cd04015; C2_plant_PLD; 1.
DR FunFam; 3.30.870.10:FF:000025; Phospholipase D delta; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR InterPro; IPR015679; PLipase_D_fam.
DR PANTHER; PTHR18896; PHOSPHOLIPASE D; 1.
DR PANTHER; PTHR18896:SF202; PHOSPHOLIPASE D ALPHA 3; 1.
DR Pfam; PF00168; C2; 1.
DR Pfam; PF00614; PLDc; 1.
DR SMART; SM00239; C2; 1.
DR SMART; SM00155; PLDc; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR PROSITE; PS50004; C2; 1.
DR PROSITE; PS50035; PLD; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000325577};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1..134
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 335..373
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
SQ SEQUENCE 641 AA; 72534 MW; 9A2EC16A31E99CF7 CRC64;
MPPLLLHGTL FATIYEIDRL SPGCGFNFGR KTGGAQKKRG GCLSEVKRLV LCQSESSRLY
ATIDLDKARV GRTRVIENEP SNPQWNESFR IYCAHEVSNV IFTIKDENPV GATLIGRAYL
PVRDIMKGYI EKWIDILDKN QSPVHGNSKI HVKLEFLDVT QDIIWSQGIK SPSFEGVPHT
FFKQRQGCKV RLYQDAHVPD GVIQPFILDG GIPHEVYRCW VGILKAIYNA KHLIYIAGWS
INAKIQLVRD QATFEPGVNP ILGQLLKSKA EEGVRVLILV WDDRTSVEAV KKDGLMATHD
QETKEYFRNT KVRCVLCPRN PDDGRSMVQG FGISTMFTHH QKTLVVDSES PEGGSQKRRI
MSFIGGIDLC DGRYDTPHHP LFSTLGSTHH DDFHQPNFPG SSITRGGPRE PWHDIHCRLE
GPVAWDVLYN FEQRWLKQAG EDKSLFSLSE LDELIIHPTE FTSSQDPETW NVQLFRSIDG
GAAAFSVPKK LHEVAEVGLV TGKDNIIDRG IQDAYINAIR RAKNFIYIEN QYFIGSSYGW
KSNDIRVEDI NALHLIPKEL SLKIVSKIKA GERFTVYIVI PMWPEGVPEG APVQAILDWQ
RRTMEMMYTD VALALQAKSL DAKLTDYLTF FCLGNREIKQ A
//
