ID A0A5J5D2C9_9PERO Unreviewed; 400 AA.
AC A0A5J5D2C9;
DT 11-DEC-2019, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 1.
DT 02-APR-2025, entry version 16.
DE RecName: Full=Fibronectin type-III domain-containing protein {ECO:0000259|PROSITE:PS50853};
GN ORFNames=FQN60_000866 {ECO:0000313|EMBL:KAA8587030.1};
OS Etheostoma spectabile (orangethroat darter).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Percoidei; Percidae; Etheostomatinae; Etheostoma.
OX NCBI_TaxID=54343 {ECO:0000313|EMBL:KAA8587030.1, ECO:0000313|Proteomes:UP000327493};
RN [1] {ECO:0000313|EMBL:KAA8587030.1, ECO:0000313|Proteomes:UP000327493}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EspeVRDwgs_2016 {ECO:0000313|EMBL:KAA8587030.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:KAA8587030.1};
RA Moran R.L., Catchen J.M., Fuller R.C.;
RT "A chromosome-level genome assembly, high-density linkage maps, and genome
RT scans reveal the genomic architecture of hybrid incompatibilities
RT underlying speciation via character displacement in darters (Percidae:
RT Etheostominae).";
RL Submitted (AUG-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAA8587030.1}.
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DR EMBL; VOFY01000013; KAA8587030.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5J5D2C9; -.
DR Proteomes; UP000327493; Chromosome 13.
DR GO; GO:0009897; C:external side of plasma membrane; IEA:TreeGrafter.
DR GO; GO:0004896; F:cytokine receptor activity; IEA:TreeGrafter.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR015321; TypeI_recpt_CBD.
DR PANTHER; PTHR23037; CYTOKINE RECEPTOR; 1.
DR PANTHER; PTHR23037:SF47; INTERLEUKIN 2 RECEPTOR SUBUNIT GAMMA; 1.
DR Pfam; PF09240; IL6Ra-bind; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 3.
DR PROSITE; PS50853; FN3; 1.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000327493};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..400
FT /note="Fibronectin type-III domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5023803110"
FT TRANSMEM 329..351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 217..314
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
SQ SEQUENCE 400 AA; 45057 MW; E3AB4FCB0639B692 CRC64;
MASKSWLTHP ATLMLLFMSW RESMHCTGLT VDPPEDLVIL DPGHLGYLEI TWSPPASLIN
MTECPILYQL EYFNTYRDSW TAIRSNRKTY SAQFDLMKDV RVRVYTLLSG PCTNGTMLKS
TSYAELVQKP PGTGVECTAV EDFVCVYHNM KHKKLEQAEE CPKYLILNGA RSGCNFTENS
LPKFTDINFC VNASSPEGPL KPIFISLQIQ NHVKPDAAEK LHLQTGPDAQ LELHWEGPVG
ILSGQCLEWE VEHSQEGPDG KISSQQISAK QMSLTLPSIR DNERSCVRVR SRLNKYCADK
SFWSEWSRPT CLPETKEVAL KSEWDTVPVY VYIAVAIIAI LVLSLCAGTV LKVKRSRQLK
KPDSTHHIVC QKLSTYICGG LKRPESLHLY RSPTAPLSDF
//
