ID A0A5J5GC69_9RHOB Unreviewed; 299 AA.
AC A0A5J5GC69;
DT 11-DEC-2019, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 1.
DT 02-APR-2025, entry version 18.
DE SubName: Full=DUF4040 domain-containing protein {ECO:0000313|EMBL:KAA9005756.1};
GN ORFNames=F3S47_17830 {ECO:0000313|EMBL:KAA9005756.1};
OS Histidinibacterium aquaticum.
OC Bacteria; Pseudomonadati; Pseudomonadota; Alphaproteobacteria;
OC Rhodobacterales; Paracoccaceae; Histidinibacterium.
OX NCBI_TaxID=2613962 {ECO:0000313|EMBL:KAA9005756.1, ECO:0000313|Proteomes:UP000326554};
RN [1] {ECO:0000313|EMBL:KAA9005756.1, ECO:0000313|Proteomes:UP000326554}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=176SS1-4 {ECO:0000313|EMBL:KAA9005756.1,
RC ECO:0000313|Proteomes:UP000326554};
RA Park J.-S., Choi H.-J.;
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B
CC family. {ECO:0000256|ARBA:ARBA00009425}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAA9005756.1}.
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DR EMBL; VYQE01000006; KAA9005756.1; -; Genomic_DNA.
DR RefSeq; WP_150446663.1; NZ_VYQE01000006.1.
DR AlphaFoldDB; A0A5J5GC69; -.
DR Proteomes; UP000326554; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR050622; CPA3_antiporter_subunitB.
DR InterPro; IPR007182; MnhB.
DR InterPro; IPR025383; MrpA_C/MbhD.
DR InterPro; IPR046806; MrpA_C/MbhE.
DR PANTHER; PTHR33932; NA(+)/H(+) ANTIPORTER SUBUNIT B; 1.
DR PANTHER; PTHR33932:SF4; NA(+)_H(+) ANTIPORTER SUBUNIT B; 1.
DR Pfam; PF13244; MbhD; 1.
DR Pfam; PF20501; MbhE; 1.
DR Pfam; PF04039; MnhB; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000326554};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..23
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 30..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 53..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 83..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 145..166
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 203..224
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 236..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 269..293
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 12..75
FT /note="MrpA C-terminal/MbhD"
FT /evidence="ECO:0000259|Pfam:PF13244"
FT DOMAIN 92..158
FT /note="MrpA C-terminal/MbhE"
FT /evidence="ECO:0000259|Pfam:PF20501"
FT DOMAIN 178..282
FT /note="Na+/H+ antiporter MnhB subunit-related protein"
FT /evidence="ECO:0000259|Pfam:PF04039"
SQ SEQUENCE 299 AA; 30391 MW; 978D690F13E90685 CRC64;
MTAVFDILLA IGILGCAAAA LAVRERTAAI AAFMVAGLLV ALSWVRLGAP DVALAEAAIG
AGLTGALLLR SARRLGPVRP RSVGWPVLGS AAILSAALAA TLAWAVASSR GISSYQSLVA
ERLSESGVTN PVTAVLLNFR AWDTLLEIAV LSVALMLVAS VGTARIRFDR LGEMMLPCAR
IVVPLLVLVS GHLLWLGSSD PGGAFQAGAV LAGAGLVLVM SGHVPTAGRA VDIARVVGLS
GLAIFVIAAS AAQVLTGGFL QFPPDVAKAW IIAIEAGLTL SIAATLVLLF LGLSRHSRS
//
