ID A0A5J5GY64_9BACI Unreviewed; 527 AA.
AC A0A5J5GY64;
DT 11-DEC-2019, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 1.
DT 18-JUN-2025, entry version 26.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN Name=dcuS {ECO:0000313|EMBL:KAA9012523.1};
GN ORFNames=F4V44_25550 {ECO:0000313|EMBL:KAA9012523.1};
OS Niallia endozanthoxylica.
OC Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae; Niallia.
OX NCBI_TaxID=2036016 {ECO:0000313|EMBL:KAA9012523.1, ECO:0000313|Proteomes:UP000326671};
RN [1] {ECO:0000313|EMBL:KAA9012523.1, ECO:0000313|Proteomes:UP000326671}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MER_TA_151 {ECO:0000313|EMBL:KAA9012523.1,
RC ECO:0000313|Proteomes:UP000326671};
RA Seuylemezian A., Vaishampayan P.;
RT "Whole genome sequences of isolates from the Mars Exploration Rovers.";
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAA9012523.1}.
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DR EMBL; VYKL01000060; KAA9012523.1; -; Genomic_DNA.
DR RefSeq; WP_150442799.1; NZ_VYKL01000060.1.
DR AlphaFoldDB; A0A5J5GY64; -.
DR OrthoDB; 9792686at2; -.
DR Proteomes; UP000326671; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR FunFam; 1.10.287.130:FF:000011; Sensor histidine kinase DcuS; 1.
DR FunFam; 3.30.450.20:FF:000018; Sensor histidine kinase DcuS; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR033463; sCache_3.
DR InterPro; IPR029151; Sensor-like_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR016120; Sig_transdc_His_kin_SpoOB.
DR InterPro; IPR039506; SPOB_a.
DR NCBIfam; NF008298; PRK11086.1; 1.
DR PANTHER; PTHR43547:SF10; SENSOR HISTIDINE KINASE DCUS; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF17203; sCache_3_2; 1.
DR Pfam; PF14689; SPOB_a; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR SUPFAM; SSF55890; Sporulation response regulatory protein Spo0B; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:KAA9012523.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000326671};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:KAA9012523.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 12..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 173..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 335..527
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 527 AA; 57804 MW; 48AA0AFCAE85D3E9 CRC64;
MHRGKLSLQN SIIFFVLAVV FISLLITEIL ISQLVADTVE NSQSEKATNV ARMVALSPLV
MEGLSGERDE SDIQTFANDI KAATNVEFVV VMDMDGIRKS HPDSSKVGKH FRGGDEGPVL
QGKEHVSISK GTLGHSLRSF TPVIDNGKQV GAVAVGITLK DVEKAVDKSR KGILIGIGLG
LLIGVIGAVV LARYIKKILL GLEPIQIARL VEERSAMLNS VREGIIATDQ DSRITLVNKS
ALSIFKKAGL DDQPIGKDVN IYMSTSRMTD VIRTGEAELD QEQEINGVIL LVNRVPIVLN
KKTVGAISTF RDKTEVRQLA GQLTGVQLYA DALRAQAHEF MNKLHVILGM VHMKNYDQLS
QYISETVNHR SNEINLVSQM MQEPVLAGFL IGKLSYAREA GVELHFSSER PIPKPQNYEM
VHELITIVGN LIDNAIDAVM DCPIKKVEAI FEYADDILTI EVSDTGTGMT EEEQNKVLQK
GYSTKGQNRG FGLHLVIQSI NKLEGEFIIS SKPGQGTEFV VYIPYNS
//
