ID A0A5N5G639_9ROSA Unreviewed; 1033 AA.
AC A0A5N5G639;
DT 26-FEB-2020, integrated into UniProtKB/TrEMBL.
DT 26-FEB-2020, sequence version 1.
DT 28-JAN-2026, entry version 23.
DE SubName: Full=Calcium-transporting ATPase 12 {ECO:0000313|EMBL:KAB2610688.1};
GN ORFNames=D8674_018720 {ECO:0000313|EMBL:KAB2610688.1};
OS Pyrus ussuriensis x Pyrus communis.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Maleae; Pyrus.
OX NCBI_TaxID=2448454 {ECO:0000313|EMBL:KAB2610688.1, ECO:0000313|Proteomes:UP000327157};
RN [1] {ECO:0000313|EMBL:KAB2610688.1, ECO:0000313|Proteomes:UP000327157}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S2 {ECO:0000313|EMBL:KAB2610688.1};
RC TISSUE=Leaf {ECO:0000313|EMBL:KAB2610688.1};
RA Ou C.;
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000327157}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Wang F., Wang J., Li S., Zhang Y., Fang M., Ma L., Zhao Y., Jiang S.;
RT "A de novo genome assembly of a pear dwarfing rootstock.";
RL Submitted (OCT-2019) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:KAB2610688.1, ECO:0000313|Proteomes:UP000327157}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S2 {ECO:0000313|EMBL:KAB2610688.1};
RC TISSUE=Leaf {ECO:0000313|EMBL:KAB2610688.1};
RA Wang F., Wang J., Li S., Zhang Y., Fang M., Ma L., Zhao Y., Jiang S.;
RT "A de novo genome assembly of a pear dwarfing rootstock.";
RL Submitted (NOV-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAB2610688.1}.
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DR EMBL; SMOL01000487; KAB2610688.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5N5G639; -.
DR OrthoDB; 1422951at2759; -.
DR Proteomes; UP000327157; Chromosome 17.
DR GO; GO:0005886; C:plasma membrane; IEA:TreeGrafter.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR GO; GO:0005388; F:P-type calcium transporter activity; IEA:TreeGrafter.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 1.20.1110.10; Calcium-transporting ATPase, transmembrane domain; 3.
DR InterPro; IPR006068; ATPase_P-typ_cation-transptr_C.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR059000; ATPase_P-type_domA.
DR InterPro; IPR036412; HAD-like_sf.
DR PANTHER; PTHR24093; CATION TRANSPORTING ATPASE; 1.
DR PANTHER; PTHR24093:SF454; CATION-TRANSPORTING P-TYPE ATPASE C-TERMINAL DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13246; Cation_ATPase; 1.
DR Pfam; PF00689; Cation_ATPase_C; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000327157};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 155..173
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 185..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 339..358
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 397..422
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 790..810
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 816..838
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 859..880
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 892..912
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 924..943
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 955..975
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1004..1021
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 222..315
FT /note="P-type ATPase A"
FT /evidence="ECO:0000259|Pfam:PF00122"
FT DOMAIN 812..977
FT /note="Cation-transporting P-type ATPase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00689"
SQ SEQUENCE 1033 AA; 114568 MW; 942FC7F25FF1D816 CRC64;
MAVEPNTEDQ ATEGASSLTA GLLIQTIEHR GTSLRRIVLG ILFSSRIRKT IRLRKASSYE
PLATASTAPD AASDHVIDIP LQERFSNNVA RIVRETDLNS LRALGGVDGI LPLLRSQFEE
GAVDGGQNPQ GWNVTKSPVD AKGFLYFLFE ACNQYTIFFL LLSAGLSFAI EFMSQGVKYG
WHDGVGILIA ALLLIAFPSV GKYRYQRKLA RKHLRYRSKL MVNVERSSTE TTPITISGVV
VGDIVHLQEG DRVPADGLFI DHGEELVLDE VLRPKIDCEN NPFVFSGSIV VKGRGRMIVT
SISANTAFAE VLSLVADHNP KEKTLLQALM DKPNACMDYL ACCVSILIAI VMLIRLLVFR
KHENYNERPE LKGQVSMNLV MRTIEKIFLK PQGKVSILAS VLATAVIGIQ HGMPFVIAVA
LFQWSNKAAK NQAVPQNLSA CVTMGLINVI CIETTAELMC NPTEVKEVWI GEEDLSIGEV
NSETDQVLKA LHQGISATAS PTNDLLISWL NTRWGSNAVL PDRRFETVEE RQLSSDEKCR
GILVRKIEND EQIMQVHCDG DAATILGMCS HYYDNRGECH NIGNQKRKLE QVIKKMEKDG
RRPIAYAYKK TQAEELTGDG LILLALVGLR CPYQEELKLA VKALREAGVS IKLVSEDEPS
IVRATASELG ISPASDDKVI EGQAFRRLNS MERPDAVDLI SVMGSSLPKD KFLMVEGLKK
KGRIVAFYGG LTIRDTLTLK EADVGIVHDI WRTGMARESA DLIIGNGCFL SKIVNSGACA
YHNIQHFSQL QLTACISGLL VTLVATMHSG ESPLTAVHLI WVNLIMCLLG GLMMVMELQG
TLQHIQRPEE RTESLITKVI RRNIAVQVLY QVSVLLILHF MPSVNEGVRN TMIFSTFTLC
QVLNLFSAMD LVKKEVLVVV LHSHWFLMAL GAVLTMQVIV VEFGKELASC VKLNALQWLI
CFTLAALSWG SDRAIKFLSA HLQRATSALR VSSRVGFSHR HRRLYILIWL FLIFSVSSYC
FHPENSQLSL YIR
//
