ID A0A5N5M8H0_PANHP Unreviewed; 1110 AA.
AC A0A5N5M8H0;
DT 26-FEB-2020, integrated into UniProtKB/TrEMBL.
DT 26-FEB-2020, sequence version 1.
DT 08-OCT-2025, entry version 19.
DE RecName: Full=C2H2-type domain-containing protein {ECO:0000259|PROSITE:PS50157};
GN ORFNames=PHYPO_G00056700 {ECO:0000313|EMBL:KAB5550686.1};
OS Pangasianodon hypophthalmus (Striped catfish) (Helicophagus hypophthalmus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Pangasiidae; Pangasianodon.
OX NCBI_TaxID=310915 {ECO:0000313|EMBL:KAB5550686.1, ECO:0000313|Proteomes:UP000327468};
RN [1] {ECO:0000313|EMBL:KAB5550686.1, ECO:0000313|Proteomes:UP000327468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Indonesia {ECO:0000313|EMBL:KAB5550686.1,
RC ECO:0000313|Proteomes:UP000327468};
RC TISSUE=Blood {ECO:0000313|EMBL:KAB5550686.1};
RA Wen M., Zahm M., Roques C., Cabau C., Klopp C., Donnadieu C., Jouanno E.,
RA Avarre J.-C., Campet M., Ha T.T.T., Dugue R., Lampietro C., Louis A.,
RA Herpin A., Echchiki A., Berthelot C., Parey E., Roest-Crollius H.,
RA Braasch I., Postlethwait J., Bobe J., Montfort J., Bouchez O., Begum T.,
RA Schartl M., Guiguen Y.;
RT "A chromosome-scale genome assembly of the striped catfish, Pangasianodon
RT hypophthalmus.";
RL Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAB5550686.1}.
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DR EMBL; VFJC01000015; KAB5550686.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A5N5M8H0; -.
DR Proteomes; UP000327468; Chromosome 14.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:TreeGrafter.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR FunFam; 3.30.160.60:FF:000110; Zinc finger protein-like; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 3.
DR InterPro; IPR051643; Transcr_Reg_ZincFinger.
DR InterPro; IPR055125; Wiz_C_Znf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24396; ZINC FINGER PROTEIN; 1.
DR PANTHER; PTHR24396:SF25; ZINC FINGER PROTEIN 644; 1.
DR Pfam; PF13894; zf-C2H2_4; 1.
DR Pfam; PF23015; zf-WIZ; 1.
DR SMART; SM00355; ZnF_C2H2; 7.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 3.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 2.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000327468};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 318..345
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 809..831
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 213..249
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 275..311
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 466..541
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 899..933
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 225..235
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 467..476
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 494..517
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 911..925
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1110 AA; 123937 MW; D707B41CE58160A1 CRC64;
MSALKENIKK EENDKPMSEI SGPLTSKPAF SSEGSVLEAS MQCPHENMTP NSDQADLLKH
VSFIDSKCAD GPAKAAYVNG SASPSISQEM LLDISKNVTG LLPKSMHTQN STNKPIIQLE
DCETLRKDGE MALRQMVTAE DVENRGIWGF DVDSPENSLD SYDDGDDLEW TPQKEFMKLL
LEDQDCSETE AKIPAASSRR KCKLDKVMMV SPTENSKNYH LGEASQKEAD PETKQSKMHS
SRSNKSQYSN GTAVAFKHLL QKPAKIVKNS QKSGYVRENL SRDSGSEEEP ALFPSNSSFK
DKAHSQTHTK NCSNQKPFIC KECGKDFYNH TSLLKHITVH QTKRRQTVEE ITGTDEITNE
GKDARLQCPQ CTFGTNCPNT FVQHAKTHEK DKRYYPCQKC NFLAASKHEL IAHMLSKHPV
TDAQCTIIRR QDVLQGQKVG KSGRKPNLVR NHKSLDKDLL FLHDSENSNC SSSPESDTQQ
SMEPEDSNGL LQTDKPKSKD TADDKMDKSE SKLDKSIHTL LSRKRNRDSE SKSTPNFEEI
SVRAESPDLG KCCIDDPLNP EEGSPSPAKC KGKLFALKDD NSVCTLKSDG NGQGFSCNND
CSKGENSSTN HKRLPSEKLT LKKSPSKRKM STPFHNLQGQ DILIDFPKCR QIFQKNSNLY
LIKKCDSKDG IHISNTTFRS PDASCDLSKQ ESGLLQTVSI KEECMETEVC GDTNISDPVV
KNGDVKVDLK SCPYCPAVFQ SGIGLSNHIR GHLHRVGVSY KARHVVSVAQ VASQDKVPPV
RRRMAAIPQI KTEVDLPLIE QPSEPKSELT CPLCREWFDT KTGLSNHVRG HLKRLGKPCS
TSTTKSPVII LKELMRDKKQ FQIKLQALEK KCRSRNSIYP FKFSNGLIIS TAKVQRFAQG
GKRHGHVSSR SAEEKKRTES NKDAMKGSPS SDLIGILKKR RAHEEAKVKT LPQTARKALL
VNAVKERDAS AQLPNSVSEK SELNRKVCVH CNATFHSGVS LSNHLRAYAR RKRNALLEGT
TYDCKRKQRS RSGSKKKTHP LLHTPEEIYR LTCRFCDLVF QGPLSVQEDW VKHLQRHIMN
TAVPHTGAAM VEVTCFPKDA NTHTHPQTSS
//
