ID   A0A5P2BGG6_STRVZ        Unreviewed;       314 AA.
AC   A0A5P2BGG6;
DT   22-APR-2020, integrated into UniProtKB/TrEMBL.
DT   22-APR-2020, sequence version 1.
DT   08-OCT-2025, entry version 12.
DE   SubName: Full=Restriction endonuclease {ECO:0000313|EMBL:QES27449.1};
GN   ORFNames=DEJ47_14155 {ECO:0000313|EMBL:QES27449.1};
OS   Streptomyces venezuelae.
OC   Bacteria; Bacillati; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=54571 {ECO:0000313|EMBL:QES27449.1, ECO:0000313|Proteomes:UP000323046};
RN   [1] {ECO:0000313|EMBL:QES27449.1, ECO:0000313|Proteomes:UP000323046}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 14583 {ECO:0000313|EMBL:QES27449.1,
RC   ECO:0000313|Proteomes:UP000323046};
RA   Kim W., Lee N., Cho B.-K.;
RT   "Streptomyces venezuelae.";
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP029193; QES27449.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A5P2BGG6; -.
DR   REBASE; 375088; Sve14583ORF14165P.
DR   OrthoDB; 9179812at2; -.
DR   Proteomes; UP000323046; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0009036; F:type II site-specific deoxyribonuclease activity; IEA:InterPro.
DR   GO; GO:0009307; P:DNA restriction-modification system; IEA:InterPro.
DR   CDD; cd22338; NaeI-like; 1.
DR   Gene3D; 3.40.600.10; DNA mismatch repair MutH/Restriction endonuclease, type II; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR037057; DNA_rep_MutH/T2_RE_sf.
DR   InterPro; IPR015210; NaeI.
DR   InterPro; IPR011335; Restrct_endonuc-II-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF09126; NaeI; 1.
DR   SUPFAM; SSF52980; Restriction endonuclease-like; 1.
PE   4: Predicted;
KW   Endonuclease {ECO:0000256|ARBA:ARBA00022759, ECO:0000313|EMBL:QES27449.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Reference proteome {ECO:0000313|Proteomes:UP000323046}.
FT   DOMAIN          3..296
FT                   /note="Type II restriction enzyme NaeI"
FT                   /evidence="ECO:0000259|Pfam:PF09126"
FT   REGION          292..314
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   314 AA;  35747 MW;  5FFC239A060D7291 CRC64;
     MLVRQHLLSL DPRGERFARV LRDTIDQLLD GEHTGRFDWN DLHKTEKTHA GTLVEINLLR
     EFELSSGADL DYLIEGIEVD CKYSQKLYGW MIPPEALDEI CLVVWADDHQ SLWSAGLLRA
     NRAKLTTSGK VTKKGNRDGK FRLTKQHHSL VTWLWHEAPL EENLLLHIDK ETQQAVLNAG
     AGTRRSPGQA KLNELFRRVQ GRRVNRTVVR TLAQQKDYMK RVRYNGGARD KLRDEGILIC
     GDYPNHQVVA AQLGLPVPQE GESVSIRVVE AKPHHDGQPR VLLEDRYWVA AGPDDPEERA
     PLLPETKKKT SSID
//