ID A0A5S4GWF3_9ACTN Unreviewed; 1042 AA.
AC A0A5S4GWF3;
DT 26-FEB-2020, integrated into UniProtKB/TrEMBL.
DT 26-FEB-2020, sequence version 1.
DT 02-APR-2025, entry version 18.
DE SubName: Full=Tetratricopeptide repeat protein {ECO:0000313|EMBL:TMR37217.1};
GN ORFNames=ETD85_08820 {ECO:0000313|EMBL:TMR37217.1};
OS Nonomuraea zeae.
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Nonomuraea.
OX NCBI_TaxID=1642303 {ECO:0000313|EMBL:TMR37217.1, ECO:0000313|Proteomes:UP000306628};
RN [1] {ECO:0000313|EMBL:TMR37217.1, ECO:0000313|Proteomes:UP000306628}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 100528 {ECO:0000313|EMBL:TMR37217.1,
RC ECO:0000313|Proteomes:UP000306628};
RA Saricaoglu S., Isik K.;
RT "Draft genome sequence of Nonomuraea zeae DSM 100528.";
RL Submitted (MAY-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TMR37217.1}.
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DR EMBL; VCKX01000018; TMR37217.1; -; Genomic_DNA.
DR RefSeq; WP_138689117.1; NZ_JBHSAZ010000076.1.
DR AlphaFoldDB; A0A5S4GWF3; -.
DR OrthoDB; 5521887at2; -.
DR Proteomes; UP000306628; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0042802; F:identical protein binding; IEA:InterPro.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011717; TPR-4.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_rpt.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR47691:SF3; HTH-TYPE TRANSCRIPTIONAL REGULATOR RV0890C-RELATED; 1.
DR PANTHER; PTHR47691; REGULATOR-RELATED; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF13424; TPR_12; 3.
DR Pfam; PF07721; TPR_4; 1.
DR Pfam; PF13176; TPR_7; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00028; TPR; 8.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 3.
DR PROSITE; PS51755; OMPR_PHOB; 1.
DR PROSITE; PS50005; TPR; 3.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU01091};
KW Reference proteome {ECO:0000313|Proteomes:UP000306628};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 1..96
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT REPEAT 826..859
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 866..899
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 906..939
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DNA_BIND 1..96
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
SQ SEQUENCE 1042 AA; 114133 MW; 4332B00D566B8272 CRC64;
MEFFLLGVMG ASVEARAIDL GTRRQRYVLA LLCLEVNRQV GIDRLIEHLW PHDPPSSCRG
IIHTYVSGLR SVFRASGAER YQVALERGRS GYLLRCDPAR IDLHRFRALT AEARTGGDDE
RRAALLERAL ALWRGPALAG VGDEQARARL TGGLEEARRT AVEDLAEARL RLGRHQGVLD
ELFALAAEFP TRPRMVGALM RALHHAGRTA EALEVYRNTR RRMAEELGLD PPAELRELQV
ALLRGDERAP PVPASRPAGT APRQLPADLT TFVGRVAELD RLLGDERAAA VVISAVDGMA
GVGKTVLAVH AAHLLAARYP DGQLFLDLHG FTHGMRPVDP ADALGRMLRV LGVPDDQIPP
DEESRAALYR TRLADRRVLV LLDNAAAEEQ VRPLLPGAPG CLVLITSRIR FTGLDDVRPL
SLDVLPTADA VALFARVTGT DRPRHLVEEI VELCGRLPLA IRTAAARLRS RPAWTVEYLA
RRLRGHQQRL DDLSGGARGV SVAIDLSYRQ VDAALRRLYR LLSLHPGADI DAYAAAAMAG
LSLSQATRAL DALVDANLLQ EPVAGRFRFH DLIRAHAADA CAREEPGAER HRATARLLDH
YTQTASLAMA ALYPYDAENR PRLATPDGPA PDVAGRREAT EWLAAELGNL LAAPHIDAGG
PSPRVVELSA ILHRHLRTRA EYSRAATLHE HAARAARTLG DRAGELEALW ALGVTRWFQG
RYAEAEEHLQ QALEIADAIG HRTGAINALH GLGHIHTMRG RHEPAVDCYR RVLDHAHAIG
HLAGELEARW GLGHIHRLRG QWGPAEESFE RAVVIARKLG HHEGELNSLY GLGHVHRLQG
RHEPALDCYQ QVMDIARESG DRVGELTALR GFGHIRLRQG AYAAAVECFE RALEIAEDTG
HRFSELHTLR GLGHAHLKQG RHERAAADFR RALDLALEIG DGNGRLQSLY GLARTCQAAG
APDRALDHYR AACDLPPEPT NDRVHVLHGM AEAHHDLGQH EQARACWRQA LDILDGLGTT
ATEEVTADLI RDRLAASPGH GG
//
