ID   A0A667HZ40_LYNCA        Unreviewed;       715 AA.
AC   A0A667HZ40;
DT   17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 1.
DT   28-JAN-2026, entry version 22.
DE   RecName: Full=Zinc finger protein 750 {ECO:0000256|ARBA:ARBA00040216};
GN   Name=ZNF750 {ECO:0000313|Ensembl:ENSLCNP00005032042.1};
OS   Lynx canadensis (Canada lynx) (Felis canadensis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Lynx.
OX   NCBI_TaxID=61383 {ECO:0000313|Ensembl:ENSLCNP00005032042.1, ECO:0000313|Proteomes:UP000472241};
RN   [1] {ECO:0000313|Ensembl:ENSLCNP00005032042.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (AUG-2025) to UniProtKB.
RN   [2] {ECO:0000313|Ensembl:ENSLCNP00005032042.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2025) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   RefSeq; XP_030152565.1; XM_030296705.2.
DR   AlphaFoldDB; A0A667HZ40; -.
DR   Ensembl; ENSLCNT00005035767.1; ENSLCNP00005032042.1; ENSLCNG00005020867.1.
DR   GeneID; 115501596; -.
DR   CTD; 79755; -.
DR   Proteomes; UP000472241; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:TreeGrafter.
DR   GO; GO:1990841; F:promoter-specific chromatin binding; IEA:TreeGrafter.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0008544; P:epidermis development; IEA:TreeGrafter.
DR   InterPro; IPR039363; ZNF750.
DR   InterPro; IPR039064; ZNF750_Znf.
DR   PANTHER; PTHR14678; PROLINE-RICH PROTEIN 35-RELATED; 1.
DR   PANTHER; PTHR14678:SF1; ZINC FINGER PROTEIN 750; 1.
DR   Pfam; PF15269; zf-C2H2_7; 1.
PE   4: Predicted;
KW   Activator {ECO:0000256|ARBA:ARBA00023159};
KW   Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000472241};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          6..57
FT                   /note="Zinc finger protein 750-like zinc finger"
FT                   /evidence="ECO:0000259|Pfam:PF15269"
FT   REGION          64..96
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          118..148
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          358..425
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          440..624
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          638..715
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        67..80
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        372..398
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        611..623
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   715 AA;  77412 MW;  81061948F8702C53 CRC64;
     MSLLKERKPK KPHYIPRPPG KPFKYKCFQC PFTCNEKSHL FNHMKYGLCK NSITLVSEQD
     RVPKCPKSNS LDPKQTNQPD TAAKPTSAKP VANGLPHFDT KLQQSLAKDD AKENVELHTR
     GPHRCPGQKS ALHEEAAPLS PAPEATRGTQ PVLEGIVRPS AFVPVGEHRL KGPEHAEAPE
     LLALPGPTAK ATSFHTKSAF HAPGYPWKAG APFLPPEFPH KIPSTKGFSA ISPYVHPAIP
     EYQPHFYTEH GLATIYSPYL LAGNSPECDA PLLSVYGTQD QRHLLPPPGP VPKHLNPPSA
     YDHYRFFQQY HSNLPIPYGF YRPESAFSSY GLRLPPVTGI SRDHSSHLLE ETALLYPALS
     PSKSSPSNTH KKNTEFEKGS PTPEAKDPSQ DGQRDTEGTK MSPRAGSAAT GSPGRPSPTN
     FTQTSQPCAG LCGLSDKPAA STLGRLHQPE HSLTAFKPVK KSTEHPNSQA LENREEPPKS
     LDAMNGDAPG ETRSASHDPE ATPSSPEDGS RTAPLNLSKK PEARPATHSP MYKDFAEVQD
     MPLNLSVKDP CNALTPRPPF HSPLQEAEPA STAAQNTDTE TSKDGPEHTQ TNQSSPDAME
     APPTTPAVKA QDARALDSSD EQKQTAAVAL CQLAAYSPGN VRMGDGEPTA PESACPQDAP
     TLSATENPEA PCDLRPRGQK RTSPRDAGKS QQGTKKTKPS DTARVFTLRK RTRVS
//