ID A0A669QIB3_PHACC Unreviewed; 430 AA.
AC A0A669QIB3;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 28-JAN-2026, entry version 23.
DE SubName: Full=Chordin like 2 {ECO:0000313|Ensembl:ENSPCLP00000020617.1};
OS Phasianus colchicus (Common pheasant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Phasianus.
OX NCBI_TaxID=9054 {ECO:0000313|Ensembl:ENSPCLP00000020617.1, ECO:0000313|Proteomes:UP000472261};
RN [1] {ECO:0000313|Ensembl:ENSPCLP00000020617.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (AUG-2025) to UniProtKB.
RN [2] {ECO:0000313|Ensembl:ENSPCLP00000020617.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2025) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR AlphaFoldDB; A0A669QIB3; -.
DR Ensembl; ENSPCLT00000028537.1; ENSPCLP00000020617.1; ENSPCLG00000018050.1.
DR OMA; HGKRYAP; -.
DR Proteomes; UP000472261; Unplaced.
DR GO; GO:0005615; C:extracellular space; IEA:TreeGrafter.
DR GO; GO:0036122; F:BMP binding; IEA:TreeGrafter.
DR GO; GO:0030154; P:cell differentiation; IEA:TreeGrafter.
DR GO; GO:0030514; P:negative regulation of BMP signaling pathway; IEA:TreeGrafter.
DR GO; GO:0048731; P:system development; IEA:UniProtKB-ARBA.
DR FunFam; 2.10.70.10:FF:000005; Chordin-like 1, isoform CRA_c; 2.
DR Gene3D; 6.20.200.20; -; 1.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 2.
DR InterPro; IPR045717; CHRDL1/2.
DR InterPro; IPR045716; CHRDL_1/2_C.
DR InterPro; IPR001007; VWF_dom.
DR PANTHER; PTHR46303:SF3; CHORDIN-LIKE PROTEIN 2; 1.
DR PANTHER; PTHR46303; VWFC DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF19548; CHRDL_1_2_C; 1.
DR Pfam; PF00093; VWC; 1.
DR Pfam; PF23334; VWC2L_2nd; 2.
DR SMART; SM00214; VWC; 3.
DR SUPFAM; SSF57603; FnI-like domain; 3.
DR PROSITE; PS01208; VWFC_1; 2.
DR PROSITE; PS50184; VWFC_2; 3.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000472261};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..430
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5025536454"
FT DOMAIN 31..96
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 109..175
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 250..315
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
SQ SEQUENCE 430 AA; 47971 MW; 1BBA47DCA976EB1D CRC64;
MLPGAGPLAF LLRCLLLLFA SESRARARPD MFCDFNGKKY SPGESWHPYL EPQGLMYCIR
CSCSENGNTR CYRIQCPALQ CASPVTDPQQ CCPRCLEPNS PSGLRAPVRS CQYNGTTYQQ
GEMFTTSELF PSRQPNQCVQ CSCSEGQIYC GLVTCPELLC SNPLTVPDSC CQVCKDGSYE
KSAEEEPLQL NRGVRHSQDQ CLGEAMNRKP PGATASTVLS SSLEFIPRSF KPKGGGGTTV
KIVLKEKHKK ACVYNGKTYS HGEVWHPVFR LYGLLPCILC TCRDGVQDCQ KITCPKEYPC
DSPEKVDGKC CKICPETRVK PTDEIITERC GKTPNHVLVY MFVPPSSENS KEILRTVAIE
KELTEEVEIY NWKLIKGIFH LIQTKKISKQ EFKQEAQNFR LITRTNEGKD PLCPPLLLGP
TTPCSRSVVT
//
