ID A0A671QC85_9TELE Unreviewed; 206 AA.
AC A0A671QC85;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 28-JAN-2026, entry version 23.
DE SubName: Full=Insulin-like growth factor binding protein 7 {ECO:0000313|Ensembl:ENSSANP00000067649.1};
OS Sinocyclocheilus anshuiensis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Cyprininae; Sinocyclocheilus.
OX NCBI_TaxID=1608454 {ECO:0000313|Ensembl:ENSSANP00000067649.1, ECO:0000313|Proteomes:UP000472260};
RN [1] {ECO:0000313|Ensembl:ENSSANP00000067649.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (AUG-2025) to UniProtKB.
RN [2] {ECO:0000313|Ensembl:ENSSANP00000067649.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2025) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR AlphaFoldDB; A0A671QC85; -.
DR Ensembl; ENSSANT00000071898.1; ENSSANP00000067649.1; ENSSANG00000033725.1.
DR Proteomes; UP000472260; Unassembled WGS sequence.
DR GO; GO:0005615; C:extracellular space; IEA:TreeGrafter.
DR GO; GO:0005520; F:insulin-like growth factor binding; IEA:InterPro.
DR GO; GO:0001558; P:regulation of cell growth; IEA:InterPro.
DR GO; GO:0009966; P:regulation of signal transduction; IEA:TreeGrafter.
DR CDD; cd00104; KAZAL_FS; 1.
DR FunFam; 4.10.40.20:FF:000006; insulin-like growth factor-binding protein 7; 1.
DR Gene3D; 3.30.60.30; -; 1.
DR Gene3D; 4.10.40.20; -; 1.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR000867; IGFBP-like.
DR InterPro; IPR011390; IGFBP_rP_mac25.
DR InterPro; IPR002350; Kazal_dom.
DR InterPro; IPR036058; Kazal_dom_sf.
DR PANTHER; PTHR14186; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-RELATED; 1.
DR PANTHER; PTHR14186:SF19; INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 7; 1.
DR Pfam; PF00219; IGFBP; 1.
DR Pfam; PF07648; Kazal_2; 1.
DR SMART; SM00121; IB; 1.
DR SMART; SM00280; KAZAL; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR SUPFAM; SSF100895; Kazal-type serine protease inhibitors; 1.
DR PROSITE; PS51323; IGFBP_N_2; 1.
DR PROSITE; PS51465; KAZAL_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Reference proteome {ECO:0000313|Proteomes:UP000472260};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..15
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 16..206
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5025661691"
FT DOMAIN 18..94
FT /note="IGFBP N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51323"
FT DOMAIN 85..138
FT /note="Kazal-like"
FT /evidence="ECO:0000259|PROSITE:PS51465"
SQ SEQUENCE 206 AA; 22231 MW; 27FF7438AC9B5F14 CRC64;
MICVLLLTLF AVVSADRLSR SCGTCDPSKC APLPAEGCSS GTLLDACGCC ELCASGTGEP
CWGRGASAKR CASGLECVKS DKDKKSKSGV CVCKSSYPVC GSDGVNYNSG CELKAASVKA
VKDKKPEIKI RNKGKCAQGE MPQHYKKLSL FKILCSFVNT DIKKNIQNRG FHGFLYNIFS
FLCQMLQFQC VNNLNLSIKI LIKIKI
//
