ID A0A672JW81_SINGR Unreviewed; 899 AA.
AC A0A672JW81;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 28-JAN-2026, entry version 24.
DE RecName: Full=Thrombospondin-like N-terminal domain-containing protein {ECO:0000259|SMART:SM00210};
OS Sinocyclocheilus grahami (Dianchi golden-line fish) (Barbus grahami).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Cyprininae; Sinocyclocheilus.
OX NCBI_TaxID=75366 {ECO:0000313|Ensembl:ENSSGRP00000000411.1, ECO:0000313|Proteomes:UP000472262};
RN [1] {ECO:0000313|Ensembl:ENSSGRP00000000411.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (AUG-2025) to UniProtKB.
RN [2] {ECO:0000313|Ensembl:ENSSGRP00000000411.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2025) to UniProtKB.
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DR AlphaFoldDB; A0A672JW81; -.
DR Ensembl; ENSSGRT00000000467.1; ENSSGRP00000000411.1; ENSSGRG00000000274.1.
DR InParanoid; A0A672JW81; -.
DR OMA; GTKQTNI; -.
DR Proteomes; UP000472262; Unassembled WGS sequence.
DR GO; GO:0005594; C:collagen type IX trimer; IEA:TreeGrafter.
DR GO; GO:0005615; C:extracellular space; IEA:TreeGrafter.
DR GO; GO:0030020; F:extracellular matrix structural constituent conferring tensile strength; IEA:TreeGrafter.
DR GO; GO:0030198; P:extracellular matrix organization; IEA:TreeGrafter.
DR FunFam; 2.60.120.200:FF:000039; Collagen XV alpha 1 chain; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 3.40.1620.70; -; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR050149; Collagen_superfamily.
DR InterPro; IPR010515; Collagenase_NC10/endostatin.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR048287; TSPN-like_N.
DR InterPro; IPR045463; XV/XVIII_trimerization_dom.
DR PANTHER; PTHR24023; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24023:SF372; COLLAGEN ALPHA-1(XVI) CHAIN; 1.
DR Pfam; PF01391; Collagen; 1.
DR Pfam; PF20010; Collagen_trimer; 1.
DR Pfam; PF06482; Endostatin; 1.
DR SMART; SM00210; TSPN; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Collagen {ECO:0000256|ARBA:ARBA00023119};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000472262};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 52..240
FT /note="Thrombospondin-like N-terminal"
FT /evidence="ECO:0000259|SMART:SM00210"
FT REGION 238..273
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 339..382
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 408..503
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 586..643
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 347..365
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 410..422
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 472..487
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 589..600
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 899 AA; 96700 MW; B497DD0C7F1D4D01 CRC64;
MLYLVKSRSP GIGLGLCFWT IILISCIPAS GCVRTRLLTL FSVCAERDSS AQLDLTELIG
VPLPPSVSFV TGLEGFPAYR FGPDANVGRL TRSFIPDPFY HDFSIVVTAR PSSRHGGVLF
AVTDALQKII HLGVSLAPVE DGSQRVVMYY TEPGAAHTQE AASFKMGDLT GRWARFTLAV
QGEEVKLYMD CEEQHRVAFR RSPDPLTFQP SSGIFIGSAG GTRLERFLGS IQQLLLTPDP
SAPNEQCEED DPYASGYGSG DDIYEDTETP DEVKKVVEER EYVMVRDTIS PLILSRAQSL
HDKLSSDLFM QIFLCFSVTA EPIRSEGASQ DRNVITMQKG EKGERGPPGP PGPAAPHTPG
EPGPRGPQGE PGRDGRPVST ASSTIAVKSS LLQNLVLRLI FIVLDSHQGP PGPPGPPGPP
GPSVGAHPGP IGLPGVPGRD GEKGKRGVPG EPGAKGDDGQ AGAPGLPGRQ GEGGEKGDMG
QKGERGIDGI CLPGSPGPPG PPGPIINLHE LMLNDTEGIF NLSGIFEPQG PLVRSLSLPC
LLFVHGLISM FWCFSETVQM DSFQCNAVKC LIMLFCEQGA KGESIIGPPG HPGPRGPPGA
PGFGRTGVAG RPGPPGPPGQ HGSGVMIPGP PGPPGRPGRA TEASSTVGKY VSLQAMRQQS
SVLEDGTLSF LIDTSKLYMK VPGGWREVQV TPQMRSAEPL ILSPQLRHTP RTHTGSALRL
VALNTPLTGN LGSIHSVNKL CRTQAQAMGI RDDYKAFLSH HLQDLIDTVQ PMYRTNTPIV
NLRGELLFKS WHSIFSSHLL PPRVPLYSFD GRDVMSDPFW PQKAVWHGSS ERGKRLSALN
CESWRAGDMA ITGQASFLYS GLLNQQTRSC SNRFIVLCIE TSHDHQTLQE RHRRWHHRS
//
