ID A0A672KN90_SINGR Unreviewed; 439 AA.
AC A0A672KN90;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 28-JAN-2026, entry version 22.
DE RecName: Full=Integrin beta-like protein 1 {ECO:0000256|ARBA:ARBA00068076};
GN Name=LOC107600373 {ECO:0000313|Ensembl:ENSSGRP00000013875.1};
OS Sinocyclocheilus grahami (Dianchi golden-line fish) (Barbus grahami).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Cyprininae; Sinocyclocheilus.
OX NCBI_TaxID=75366 {ECO:0000313|Ensembl:ENSSGRP00000013875.1, ECO:0000313|Proteomes:UP000472262};
RN [1] {ECO:0000313|Ensembl:ENSSGRP00000013875.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (AUG-2025) to UniProtKB.
RN [2] {ECO:0000313|Ensembl:ENSSGRP00000013875.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2025) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR AlphaFoldDB; A0A672KN90; -.
DR Ensembl; ENSSGRT00000014990.1; ENSSGRP00000013875.1; ENSSGRG00000008623.1.
DR Proteomes; UP000472262; Unassembled WGS sequence.
DR GO; GO:0009986; C:cell surface; IEA:TreeGrafter.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005925; C:focal adhesion; IEA:TreeGrafter.
DR GO; GO:0008305; C:integrin complex; IEA:TreeGrafter.
DR GO; GO:0005178; F:integrin binding; IEA:TreeGrafter.
DR GO; GO:0033627; P:cell adhesion mediated by integrin; IEA:TreeGrafter.
DR GO; GO:0016477; P:cell migration; IEA:TreeGrafter.
DR GO; GO:0098609; P:cell-cell adhesion; IEA:TreeGrafter.
DR GO; GO:0007160; P:cell-matrix adhesion; IEA:TreeGrafter.
DR GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:TreeGrafter.
DR FunFam; 2.10.25.10:FF:000249; Integrin subunit beta like 1; 2.
DR FunFam; 2.10.25.10:FF:000042; Integrin subunit beta-like 1; 3.
DR FunFam; 2.10.25.10:FF:000175; Integrin subunit beta-like 1; 1.
DR Gene3D; 2.10.25.10; Laminin; 9.
DR InterPro; IPR013111; EGF_extracell.
DR InterPro; IPR057073; EGF_integrin_2.
DR InterPro; IPR015812; Integrin_bsu.
DR InterPro; IPR057243; Integrin_I-EGF_CS.
DR PANTHER; PTHR10082; INTEGRIN BETA SUBUNIT; 1.
DR PANTHER; PTHR10082:SF60; INTEGRIN BETA-PS; 1.
DR Pfam; PF07974; EGF_2; 5.
DR Pfam; PF23105; EGF_integrin; 2.
DR SUPFAM; SSF57196; EGF/Laminin; 7.
DR PROSITE; PS00243; I_EGF_1; 5.
DR PROSITE; PS52047; I_EGF_2; 7.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000472262};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..439
FT /note="Integrin beta-like protein 1"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5025472324"
FT DOMAIN 50..84
FT /note="Epidermal growth factor-like"
FT /evidence="ECO:0000259|Pfam:PF07974"
FT DOMAIN 137..162
FT /note="Epidermal growth factor-like"
FT /evidence="ECO:0000259|Pfam:PF07974"
FT DOMAIN 231..256
FT /note="Epidermal growth factor-like"
FT /evidence="ECO:0000259|Pfam:PF07974"
FT DOMAIN 269..308
FT /note="Integrin beta epidermal growth factor-like"
FT /evidence="ECO:0000259|Pfam:PF23105"
FT DOMAIN 314..344
FT /note="Epidermal growth factor-like"
FT /evidence="ECO:0000259|Pfam:PF07974"
FT DOMAIN 358..395
FT /note="Integrin beta epidermal growth factor-like"
FT /evidence="ECO:0000259|Pfam:PF23105"
FT DOMAIN 401..431
FT /note="Epidermal growth factor-like"
FT /evidence="ECO:0000259|Pfam:PF07974"
SQ SEQUENCE 439 AA; 47773 MW; 7E91E1AF14E3CAA3 CRC64;
LNMHAETLVN SVLGALLLIL LSAVQGSLQQ SLRQVGGECK ISPESSLRRC RTPDGLICSG
RGECECGICI CQVTEPGTFY GPRCECHDWI CPTYDGKTCG GTCHCGSCMC HNPDGKGLVS
GRYCECDDSE CLEEDSGDMC GGHGKCYCGN CYCSAGWHGD KCEFQCDISP WESKQRCTSP
DGKICSNRGT CVCGECTCYD VDPSGDWGDI HGETCECDER SCHAMYDRYS DDFCSGRGQC
NCGRCDCKEG WAGKKCDHPH SCSLSMEASQ KKCRGTSSLL CFGRGQCLCG QCTCHPPGDK
RVHGKNCECD DRQCEDLNRE ICGGHGFCSC GRCICSDGWF GKHCQFPRSC DMTDEQSKSL
CEMADGVICS GKGSCHCGRC ICSPQEWYIS GEFCECDDRE CDKHDGLVCT GNGVCNCGNC
DCWDGWTGNA CEIWVGEEY
//
