ID A0A672MDY9_SINGR Unreviewed; 614 AA.
AC A0A672MDY9;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 28-JAN-2026, entry version 23.
DE RecName: Full=Zinc finger protein 750 {ECO:0000256|ARBA:ARBA00040216};
GN Name=LOC107599316 {ECO:0000313|Ensembl:ENSSGRP00000035014.1};
OS Sinocyclocheilus grahami (Dianchi golden-line fish) (Barbus grahami).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Cyprininae; Sinocyclocheilus.
OX NCBI_TaxID=75366 {ECO:0000313|Ensembl:ENSSGRP00000035014.1, ECO:0000313|Proteomes:UP000472262};
RN [1] {ECO:0000313|Ensembl:ENSSGRP00000035014.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (AUG-2025) to UniProtKB.
RN [2] {ECO:0000313|Ensembl:ENSSGRP00000035014.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2025) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_016146354.1; XM_016290868.1.
DR AlphaFoldDB; A0A672MDY9; -.
DR FunCoup; A0A672MDY9; 890.
DR Ensembl; ENSSGRT00000037581.1; ENSSGRP00000035014.1; ENSSGRG00000019397.1.
DR GeneID; 107599316; -.
DR KEGG; sgh:107599316; -.
DR InParanoid; A0A672MDY9; -.
DR OMA; PSAYDHY; -.
DR OrthoDB; 8933073at2759; -.
DR Proteomes; UP000472262; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:TreeGrafter.
DR GO; GO:1990841; F:promoter-specific chromatin binding; IEA:TreeGrafter.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0008544; P:epidermis development; IEA:TreeGrafter.
DR InterPro; IPR039363; ZNF750.
DR InterPro; IPR039064; ZNF750_Znf.
DR PANTHER; PTHR14678; PROLINE-RICH PROTEIN 35-RELATED; 1.
DR PANTHER; PTHR14678:SF1; ZINC FINGER PROTEIN 750; 1.
DR Pfam; PF15269; zf-C2H2_7; 1.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000472262};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 5..58
FT /note="Zinc finger protein 750-like zinc finger"
FT /evidence="ECO:0000259|Pfam:PF15269"
FT REGION 68..121
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 328..356
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 371..443
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 550..614
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 79..121
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 375..391
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 398..407
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 429..438
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 550..559
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 582..599
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 614 AA; 69357 MW; E0827C4833C63D15 CRC64;
MDTLQGRKPK KPHYIPRPAG KPFKYQCFQC PFTCNIKSHL FNHMKYNLCK NSISLVSQRM
EQTGKMQRTS QHNFPFNHKS KEPPLEAEAN KPTERVNDKV EQEEMGKGTR ETPESPIKEV
TKDAPEPICE TRDKNGDIDI EQNKIYSAFS PVAQTCEREA LSRSPHKDDQ SSSAIPQFYH
QMAPWVPPAS TAPLLPLITD YPSYMVSERP LHSLYTPYSH NQANTPAYQL TSRETQRPLV
PSPLVPPSTS LFHPYHYRYG HSIIPGPPLP YSIYQHPEFP MSLQRTRYLP LDVYSNRFYL
REYGGHLVPL PHPDSYSRLP EDRAFQEHNT VDKGTRQSPI AGCAASGSPD RPSTADVTQR
IPVTLRHASH GESFPVSQSQ HVEPAATTAT ENLPKKSCGQ TQESMLQNKE RNEPQTTASA
RSCEISSEKE DEETEEEPAP LNLSKRDRAV SSNMTHHYSD CELHYDSESS QEEAPLNLCL
RVQSNNLALP NTTGSDTPER QTIINAEVCT IVPPREQEID PCDQRHSAAF ALCQLASSKD
IIIDSSIDQQ EMTEGQNSQS PPPPDKSPAK DTPDTPKQST RGQKRVNNRP LRHTNKRAKV
KEPARTQRKR SQNC
//
