ID   A0A672YI14_9TELE        Unreviewed;       891 AA.
AC   A0A672YI14;
DT   17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 1.
DT   10-JUN-2026, entry version 23.
DE   SubName: Full=POP1 homolog, ribonuclease P/MRP subunit {ECO:0000313|Ensembl:ENSSORP00005004222.1};
OS   Sphaeramia orbicularis (orbiculate cardinalfish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Gobiaria; Kurtiformes; Apogonoidei; Apogonidae; Apogoninae; Sphaeramia.
OX   NCBI_TaxID=375764 {ECO:0000313|Ensembl:ENSSORP00005004222.1, ECO:0000313|Proteomes:UP000472271};
RN   [1] {ECO:0000313|Ensembl:ENSSORP00005004222.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Wellcome Sanger Institute Data Sharing;
RL   Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSSORP00005004222.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JAN-2026) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   AlphaFoldDB; A0A672YI14; -.
DR   Ensembl; ENSSORT00005004348.1; ENSSORP00005004222.1; ENSSORG00005001741.1.
DR   Proteomes; UP000472271; Chromosome 16.
DR   GO; GO:0005655; C:nucleolar ribonuclease P complex; IEA:InterPro.
DR   GO; GO:0000172; C:ribonuclease MRP complex; IEA:InterPro.
DR   GO; GO:0001682; P:tRNA 5'-leader removal; IEA:InterPro.
DR   InterPro; IPR039182; Pop1.
DR   InterPro; IPR055079; POP1_C.
DR   InterPro; IPR009723; Pop1_N.
DR   InterPro; IPR012590; POPLD_dom.
DR   PANTHER; PTHR22731; RIBONUCLEASES P/MRP PROTEIN SUBUNIT POP1; 1.
DR   PANTHER; PTHR22731:SF3; RIBONUCLEASES P_MRP PROTEIN SUBUNIT POP1; 1.
DR   Pfam; PF22770; POP1_C; 1.
DR   Pfam; PF06978; POP1_N; 2.
DR   Pfam; PF08170; POPLD; 1.
PE   4: Predicted;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000472271};
KW   tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT   DOMAIN          62..128
FT                   /note="Pop1 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF06978"
FT   DOMAIN          135..202
FT                   /note="Pop1 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF06978"
FT   DOMAIN          544..635
FT                   /note="POPLD"
FT                   /evidence="ECO:0000259|Pfam:PF08170"
FT   DOMAIN          729..878
FT                   /note="POP1 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF22770"
FT   REGION          17..51
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          303..359
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          763..790
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        42..51
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        303..312
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        347..359
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   891 AA;  100252 MW;  DF439B949C01FA91 CRC64;
     MLYTVLSPYL FTDETTILPK GGDPSTNRPK RSHHQPGWVR GHQKDGGDYS KEMPKYITAG
     GFARARAAEV KAMLKAVTKR PASCHVFETL PKHMRRRAMS HNTKRLPRRL RLMKKKEQTR
     SKSRKARRRH GNLLLEFNRR QRKNIWLETH IWHAKRFHMV KKWGYCLGDR PTYKCYRPCY
     RAMSSHCLLQ DLSYYCCIEL QGEEDRLLTG LSQLTSKEAG PTFAAALCLS GRRQGSVVVY
     RAGQYPSQPL GPVTFLWRPR TQGSTHRQLW IWAHPTLKQD LLAELRSVCD CSEAVVPVVV
     PEPSPAEVTP TVDSEPKPKT TPGAKRKRSS KDQSGPPAKK ILGDGTRSPT TPVTWKSSSS
     TTVINDLTME IIRYRLIGPQ SHTVITEAFE AATSCDPSSL WWPEHCKDEN KMHLHQQQAD
     VFHLLKGIFS TAELPPGTIL GLTVDDPRLT LPTKKVKALP CEKRRELVLS GVSEHCCQSF
     LWDRSVRDNV IDNKISEQEL NRMRSEVLVP GSRLPVPPQG RVPVLLVHQP GKQVGHEMSS
     WGAGWDLLLP KGWGMAFWVP LVYRGVRIGG LNMSLKHSQN KSAPHFPHDY PDCPAGVHFQ
     EEQEAELLDK FKRRPPAKRT NYIKHGCLAP FCCPWQQLAE EWEHITREGG EEREGAGRSR
     TTTEADTVME GRWRPLVRII RTHSSLRLLS GWCKPTTSKG QRACRLRLPP PSLDLSAVKS
     FLTSHRMTLV WVRLSLLSGG KPELHGIVCV PTSEDLKQLK ASKKAAAPSL PSDKTVEKET
     ELSSASDPNI PITSSSPLDL VLGLWPDPLP SVASHCSRLT LGWVTQGDFS LSAGCGEALG
     FVSVPGLLNT LQNQPMEHRG TVLLRNPTSL QYRFAKINTR SEPMHKFSYC Q
//