ID A0A673A936_9TELE Unreviewed; 98 AA.
AC A0A673A936;
DT 17-JUN-2020, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 1.
DT 18-JUN-2025, entry version 21.
DE RecName: Full=FXYD domain-containing ion transport regulator {ECO:0000256|RuleBase:RU364131};
GN Name=LOC115436443 {ECO:0000313|Ensembl:ENSSORP00005025801.1};
OS Sphaeramia orbicularis (orbiculate cardinalfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Gobiaria; Kurtiformes; Apogonoidei; Apogonidae; Apogoninae; Sphaeramia.
OX NCBI_TaxID=375764 {ECO:0000313|Ensembl:ENSSORP00005025801.1, ECO:0000313|Proteomes:UP000472271};
RN [1] {ECO:0000313|Ensembl:ENSSORP00005025801.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Wellcome Sanger Institute Data Sharing;
RL Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSORP00005025801.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2025) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the FXYD family. {ECO:0000256|ARBA:ARBA00005948,
CC ECO:0000256|RuleBase:RU364131}.
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DR RefSeq; XP_030015184.1; XM_030159324.1.
DR RefSeq; XP_030015185.1; XM_030159325.1.
DR AlphaFoldDB; A0A673A936; -.
DR Ensembl; ENSSORT00005026569.1; ENSSORP00005025801.1; ENSSORG00005012404.1.
DR GeneID; 115436443; -.
DR InParanoid; A0A673A936; -.
DR Proteomes; UP000472271; Chromosome 16.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0017080; F:sodium channel regulator activity; IEA:TreeGrafter.
DR GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR GO; GO:0043269; P:regulation of monoatomic ion transport; IEA:InterPro.
DR CDD; cd20324; FXYD6; 1.
DR Gene3D; 1.20.5.780; Single helix bin; 1.
DR InterPro; IPR000272; Ion-transport_regulator_FXYD.
DR PANTHER; PTHR14132:SF15; FXYD DOMAIN-CONTAINING ION TRANSPORT REGULATOR 6-RELATED; 1.
DR PANTHER; PTHR14132; SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA; 1.
DR Pfam; PF02038; ATP1G1_PLM_MAT8; 1.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|RuleBase:RU364131}; Membrane {ECO:0000256|RuleBase:RU364131};
KW Reference proteome {ECO:0000313|Proteomes:UP000472271};
KW Signal {ECO:0000256|RuleBase:RU364131};
KW Transmembrane {ECO:0000256|RuleBase:RU364131};
KW Transmembrane helix {ECO:0000256|RuleBase:RU364131};
KW Transport {ECO:0000256|RuleBase:RU364131}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|RuleBase:RU364131"
FT CHAIN 19..98
FT /note="FXYD domain-containing ion transport regulator"
FT /evidence="ECO:0000256|RuleBase:RU364131"
FT /id="PRO_5025708834"
FT TRANSMEM 46..67
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364131"
FT REGION 75..98
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 77..98
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 98 AA; 10910 MW; 3F8D7B8C2467829F CRC64;
MDLLLLTAFS TWLAPALGSA FGREVFASAA DDDKDYDVSF HYDYESLRIG GLVFAVVLFL
MGIALIATRK CTCSKSNETR PRDPDVETNR VRDSNDQK
//
